(1) The effect of various fractions of chalone--containing preparation from ascyte Ehrlich's tumour obtained by high performance liquid chromatography (HPLC) on mitotic activity and DNA synthesis in the tumour has been studied.
(2) It was also found that the maximum number of dividing cells was at the wound edge in the group wounded at 09.00 h, which also agrees with the chalone concept.
(3) Thus the circadian rhythms and S-phase lengths of the test tissues need to be considered when experiments are performed with chalones.
(4) We show here that in our granulocytic and lymphocytic chalones polyamines, either free or bound, are not responsible for the inhibitory effects of the preparation.
(5) Some definite regularities were revealed in the change of the power of linkage among the cells of liver parenchyma after the disturbance of its innervation and chalones affected.
(6) A "negative feedback" mechanism of control with chalone, a tissue-specific, species-nonspecific inhibitor of mitosis, has been suggested by Bullough and Laurence.
(7) Theophylline (an inhibitor of cyclic nucleotide phosphodiesterase) or epidermal chalone inhibited mitoses and enhanced KG production.
(8) However, it is evident that the tumour cells react less than the epidermis to both the G1 and the G2 chalone, and thus the findings of this study do not provide any evidence against the theory that epidermoid transplanted tumours are less sensitive to epidermal chalones than normal tissue of the same histogenetic origin.
(9) The model has been developed to take into account the chalone mechanism of hemopoiesis regulation.
(10) It is suggested that chalones be used both as regulators of cell multiplication and as markers of histogenesis.
(11) It is based on the theory of chalone regulation of hematopoiesis.
(12) Choleragenoid did not block inhibition of mitogen stimulation by a lymphocyte chalone preparation indicating that a different mechanism may be involved with the chalone.
(13) It was prepared from a bovine spleen acetone powder and found to be associated partly with high molecular weight carriers in the form of an active complex characterized previously as part of a 'lymphoid chalone' fraction.
(14) Here there was initially a depression of the mitotic rate and a low concentration of G2 chalone.
(15) In contrast to the G1-chalone preparation, aphidicolin, a potent inhibitor of DNA polymerase alpha, clearly shows S-phase-specific inhibition.
(16) Chalone treatment also resulted in an enhancement of erythropoiesis and megakaryopoiesis, and in phenomena some of which were totally unexpected, such as immunostimulation and a remarkable resistance to bacterial infections in the presence of extreme granulocytopenia.
(17) To explain these observations, it is assumed that the epidermal stem cell population is heterogeneous consisting of G1 chalone-sensitive and G1 chalone-insensitive cells.
(18) However, the titers of erythropoietin and medium molecules rose whereas the titer of erythrocytic chalones was reduced.
(19) Using a recently developed method of culturing T-lymphocyte colonies in agar-containing capillary tubes, the capacity of three different lymphoid extracts with lymphocyte chalone (LC) activity to inhibit colony growth was demonstrated.
(20) An additional advantage is that the capillaries provide a basis for a simple and reliable assay system for determining regulatory factors of lymphocyte proliferation (including chalones).
Dialect
Definition:
(n.) Means or mode of expressing thoughts; language; tongue; form of speech.
(n.) The form of speech of a limited region or people, as distinguished from ether forms nearly related to it; a variety or subdivision of a language; speech characterized by local peculiarities or specific circumstances; as, the Ionic and Attic were dialects of Greece; the Yorkshire dialect; the dialect of the learned.
Example Sentences:
(1) Historical reality suggests the concept of socially necessary risk determined through the dialectic process in democracy.
(2) This is contrasted with the dialectical materialist concept of psychic phenomena as the highest integration level of man's relationship to the environment.
(3) This study investigated whether Nonstandard English (NSE) dialect responses to an examiner-constructed sentence completion test were congruent with and predictive of use of NSE during spontaneous conversation.
(4) We conclude that no major dialect differences exist in peptic ulcer frequency amongst the Chinese in Singapore.
(5) The hypothesis is advanced that both phenomena represent inborn dialectical logical instruments of evolution-like human identity creation and maintenance.
(6) Discussion of a revised model of Erikson's eight stages of psychosocial development illustrates the importance of formulating a dialectical developmental model that describes the interaction between attachment and separation and between product and process.
(7) Strong individual differences and learned local dialects are common.
(8) The Freudian conception of the process by which the subject is constituted is fundamentally dialectical in nature and involves the notion that the subject is created and sustained (and at the same time decentred from itself) through the dialectical interplay of consciousness and unconsciousness.
(9) This dialectic is defined as the synthesis of the antithetical strategies of Dealing With It and Keeping It in Its Place in which people are able to transcend each strategy and sustain hope.
(10) Chinese New Year is a public holiday and in Glodok, Mandarin and other dialects are spoken openly.
(11) For example such problems are discussed: the dialectic association of activity and inactivity of needing care old age people, the relation between energy and personality of old age people, change of relations between doctor-nurse-citizen or the higher responsibility of the doctor of the houses for old age people in connection with so-called "Triage".
(12) A dialectical model is proposed in which BSG utilization rates are seen as the product of an avoidance-avoidance conflict involving the choice between suffering emotional distress on one's own or the perceived stigma of joining a BSG.
(13) There were still quite a few Marxists at Oxford in those days – Terry Eagleton and his clique were seemingly bolted to the same table in the King’s Arms the entire time I was an undergraduate – but while I was silly and naive enough to believe in the purifying, energising effects of violent revolution, I wasn’t obtuse enough to think of dialectical materialism as anything more than a powerful heuristic.
(14) A cult of healing through meditation that was observed in Bangkok, Thailand in 1974 is described, and the cult is interpreted in terms of two axes, the cosmological and the performative, and the dialectical, reciprocal and complementary relations between them.
(15) Starting from these statements, the author considers the hereditary and the environmental factors as a dialectical unit, associates the implications of both groups of factors with typical forms of dysgnathias and draws conclusions as to the prognosis of "mainly genetically" and "mainly environmentally" induced dental and occlusal malpositions.
(16) Cantonese is the common Chinese dialect spoken by the citizens in Hong Kong.
(17) The name of these drugs, Chin-I, dialectal Kim-Iya, was Arabicized as Kimiya and transliterated Chemeia by the Copts.
(18) The data, failing to produce evidence for an "undershoot" mechanism, support the view that dialect-specific correlates of stress are actively safeguarded by means of articulatory reorganization.
(19) Postmortem findings will continue to be a valid basis on which medical specialists can train their own medical thinking and can learn about the dialectics of pathological processes.
(20) The clustering in the present song, however, may also be due to a tendency for a mid vowel to be realized as a higher-beginning diphthong, which is characteristic of the North-Estonian coastal dialect area where the singers come from.