(n.) A venereal sore or ulcer; specifically, the initial lesion of true syphilis, whether forming a distinct ulcer or not; -- called also hard chancre, indurated chancre, and Hunterian chancre.
Example Sentences:
(1) Venereal Disease Research Laboratories (VDRL) and Treponema pallidum hemagglutination (TPHA) tests became positive during hospitalization, and dark-field examination was positive for Treponemas, thus allowing the diagnosis of chancre of the rectum.
(2) Provided goats were immunized, it was found that the chancre reaction could be used to distinguish different populations of T. congolense.
(3) Local skin reactions (chancres) developed at the sites of inoculation with Trypanosoma evansi in rabbits and calves.
(4) Following the tsetse bite, the trypanosomes in the skin multiplied, reaching maximum numbers when the skin reaction (chancre) of the host attained its maximum size.
(5) In a preliminary study, two of four rabbits infected with human T-cell leukemia virus type I (HTLV-I) demonstrated prolonged primary chancres following superinfection with Treponema pallidum, the causative agent of syphilis.
(6) A chancre sore was infrequent in children; condylomata lata was the most frequent cutaneous lesion (80.9%).
(7) Clinically the patients with abnormal liquor developed multiple chancres, erosive papules, leukoderma, alopecia, neutrophilia; these patients had suffered from various diseases in the past.
(8) Certain types such as "chancre mou volant," however, could not be found in the present material.
(9) Expression of nine metacyclic variable antigen types (M-VATs) of Trypanosoma congolense in chancres from infected rabbits was determined using monoclonal antibodies raised against metacyclic forms of trypanosomes.
(10) After cutaneous inoculation of viable Treponema pallidum subsp pallidum into the skin of chancre-immune or previously uninfected rabbits, organisms move from perivascular connective tissue to localize extracellularly in hair follicles, erector pili muscles, and cutaneous nerves.
(11) The first symptom was a lesion, or chancre, in the genital region.
(12) A description is given of the structure of the basic cellular elements found in the chancres, particularly the plasma cells since it is in them that the main immunological processes take place.The morphology of the treponemes varies in the course of the pathological process as well as with the type of cell harbouring them.
(13) In calves, similar changes were observed although there were fewer trypanosomes present in the chancre and the cellular involvement was less extensive than that seen in the rabbit.
(14) In addition, HIV-infected rabbits demonstrate prolonged cutaneous lesions (chancres) after intracutaneous challenge with T. pallidum, the causative agent of syphilis.
(15) Sensitization and repetitive elicitation with P. acnes did not change the time of appearance or progression of syphilitic chancres after i.v or i.d.
(16) A clinical, bacteriological and serological pictures of 45 patients with chancriform pyoderma are presented, A single ulcer (92.8%), localized on genitals (91.1%) in adult males (93.3%), imitating or very similar to syphilitic primary chancre in our material was observed.
(17) A brief introduction on trypanosomiasis in ruminants and an explanation of the term chancre are followed by a discussion of a number of findings on the early pathogenesis of the disease.
(18) Local skin reactions (chancres) developed in goats at the sites of deposition, by tsetse flies, of metacyclics of Trypanosoma congolense.
(19) A case of primary tuberculous chancre of the vulva is reported.
(20) In long-standing chancres cyst-like formations with multi-layered membranes have been found.
Chancroid
Definition:
(n.) A venereal sore, resembling a chancre in its seat and some external characters, but differing from it in being the starting point of a purely local process and never of a systemic disease; -- called also soft chancre.
Example Sentences:
(1) Sixteen patients with clinical chancroid were studied prospectively; different culture media and sampling techniques from genital lesions were evaluated.
(2) In a retrospective study of 53 patients with chancroid seen at this clinic during this period, the results of smears were positive in 82% and of cultures in 84% (of those for whom cultures had been performed).
(3) These results showed that a 200 or 400 mg single dose of oral fleroxacin is an efficacious treatment for men with microbiologically confirmed chancroid who are not HIV-1 infected.
(4) Chancroid is a sexually transmitted disease characterized by genital ulceration.
(5) These strategies now permit localized introductions of chancroid into developed countries to be contained rapidly.
(6) This paper reviews the epidemiology, diagnosis and management of chancroid.
(7) dwarf, giant and phagedaenic chancroid were also seen.
(8) Direct inoculation by swab to CA + v from chancroidal ulcers is effective as an isolation technique for growth of H. ducreyi.
(9) Haemophilus ducreyi is the etiological agent of chancroid.
(10) One hundred and thirty six patients with chancroid were treated with four different treatment regimens; (A) Sulphaphenazole 1 g 12 hourly by mouth x 10 days (B) Inj streptomycin 1 g intramuscularly daily with sulphaphenazole 1 g 12 hourly orally x 10 days; (C) trimethoprim 200 mg 12 hourly by mouth x 7-10 days, and (D) erythromycin 500 mg 6 hourly orally x 7-10 days.
(11) Gonorrhea, chancroid, nongonococcal urethritis, and syphilis are still the major STDs.
(12) After 35 observations of the chancroid observed in the department of dermato-venereology of the University Hospital of Tlemcen (West Algeria) from August 1988 to December 1991, we are led to analyze the flare of this sexual transmitted disease.
(13) From June to November 1987 an outbreak of chancroid occurred in Winnipeg, the first in more than 10 years; 14 people (9 men, 5 women) were involved.
(14) Increasing resistance of Haemophilus ducreyi to antimicrobials necessitates further trials of new antimicrobial agents for treating chancroid.
(15) Overall, the accuracy of clinical diagnosis was 68% for single infections, 80% for chancroid, 55% for primary syphilis, 27% for lymphogranuloma venereum (LGV), and 22% for genital herpes.
(16) These MAbs may permit the development of rapid and efficient immunodiagnostics for chancroid.
(17) Chancroid is the most prevalent form of genital ulcer disease in developing countries and is undergoing a resurgence in industrialized countries.
(18) Chancroid is a sexually transmitted disease caused by Haemophilus ducreyi.
(19) This may explain the lack of specificity of the adsorption EIA in areas where chancroid is endemic.
(20) There was no evidence of syphilis, chancroid, or herpes simplex virus infection.