(n.) A venereal sore or ulcer; specifically, the initial lesion of true syphilis, whether forming a distinct ulcer or not; -- called also hard chancre, indurated chancre, and Hunterian chancre.
Example Sentences:
(1) Venereal Disease Research Laboratories (VDRL) and Treponema pallidum hemagglutination (TPHA) tests became positive during hospitalization, and dark-field examination was positive for Treponemas, thus allowing the diagnosis of chancre of the rectum.
(2) Provided goats were immunized, it was found that the chancre reaction could be used to distinguish different populations of T. congolense.
(3) Local skin reactions (chancres) developed at the sites of inoculation with Trypanosoma evansi in rabbits and calves.
(4) Following the tsetse bite, the trypanosomes in the skin multiplied, reaching maximum numbers when the skin reaction (chancre) of the host attained its maximum size.
(5) In a preliminary study, two of four rabbits infected with human T-cell leukemia virus type I (HTLV-I) demonstrated prolonged primary chancres following superinfection with Treponema pallidum, the causative agent of syphilis.
(6) A chancre sore was infrequent in children; condylomata lata was the most frequent cutaneous lesion (80.9%).
(7) Clinically the patients with abnormal liquor developed multiple chancres, erosive papules, leukoderma, alopecia, neutrophilia; these patients had suffered from various diseases in the past.
(8) Certain types such as "chancre mou volant," however, could not be found in the present material.
(9) Expression of nine metacyclic variable antigen types (M-VATs) of Trypanosoma congolense in chancres from infected rabbits was determined using monoclonal antibodies raised against metacyclic forms of trypanosomes.
(10) After cutaneous inoculation of viable Treponema pallidum subsp pallidum into the skin of chancre-immune or previously uninfected rabbits, organisms move from perivascular connective tissue to localize extracellularly in hair follicles, erector pili muscles, and cutaneous nerves.
(11) The first symptom was a lesion, or chancre, in the genital region.
(12) A description is given of the structure of the basic cellular elements found in the chancres, particularly the plasma cells since it is in them that the main immunological processes take place.The morphology of the treponemes varies in the course of the pathological process as well as with the type of cell harbouring them.
(13) In calves, similar changes were observed although there were fewer trypanosomes present in the chancre and the cellular involvement was less extensive than that seen in the rabbit.
(14) In addition, HIV-infected rabbits demonstrate prolonged cutaneous lesions (chancres) after intracutaneous challenge with T. pallidum, the causative agent of syphilis.
(15) Sensitization and repetitive elicitation with P. acnes did not change the time of appearance or progression of syphilitic chancres after i.v or i.d.
(16) A clinical, bacteriological and serological pictures of 45 patients with chancriform pyoderma are presented, A single ulcer (92.8%), localized on genitals (91.1%) in adult males (93.3%), imitating or very similar to syphilitic primary chancre in our material was observed.
(17) A brief introduction on trypanosomiasis in ruminants and an explanation of the term chancre are followed by a discussion of a number of findings on the early pathogenesis of the disease.
(18) Local skin reactions (chancres) developed in goats at the sites of deposition, by tsetse flies, of metacyclics of Trypanosoma congolense.
(19) A case of primary tuberculous chancre of the vulva is reported.
(20) In long-standing chancres cyst-like formations with multi-layered membranes have been found.
Disease
Definition:
(n.) Lack of ease; uneasiness; trouble; vexation; disquiet.
(n.) An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc.
(v. t.) To deprive of ease; to disquiet; to trouble; to distress.
(v. t.) To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased.
Example Sentences:
(1) Forty-nine patients (with 83 eyes showing signs of the disease) were followed up for between six months and 12 years.
(2) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(3) A 2.5-month-old child with cyanotic heart disease who required long-term PGE1 infusions; developed widespread periosteal reactions during the course of therapy.
(4) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(5) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(6) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(7) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(8) We considered the days of the disease and the persistence of symptoms since the admission as peculiar parameters between the two groups.
(9) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(10) Coronary arteritis has to be considered as a possible etiology of ischemic symptoms also in subjects who appear affected by typical atherosclerotic ischemic heart disease.
(11) Of 19 patients with coronary artery disease and "normal" omnicardiograms, only 8 (42%) had normal ventricular angiography.
(12) A disease in an IgD (lambda) plasmocytoma is described, where after therapy with Alkeran and prednisone a disappearance of all clinical and laboratory findings indicating an activity could be observed.
(13) In order to control noise- and vibration-caused diseases it was necessary not only to improve machines' quality and service conditions but also to pay special attention to the choice of operators and to the quality of monitoring their adaptation process.
(14) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(15) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(16) Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis.
(17) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
(18) Road traffic accidents (RTAs) comprised 40% and ischaemic heart disease (IHD) 13% of the total.
(19) We measured soluble CD8 (sCD8) levels in the CSF of patients with MS, other inflammatory neurologic diseases (INDs), and noninflammatory neurologic diseases (NINDs).
(20) Measurement of urinary GGT levels represents a means by which proximal tubular disease in equidae could be diagnosed in its developmental stages.