(n.) A venereal sore or ulcer; specifically, the initial lesion of true syphilis, whether forming a distinct ulcer or not; -- called also hard chancre, indurated chancre, and Hunterian chancre.
Example Sentences:
(1) Venereal Disease Research Laboratories (VDRL) and Treponema pallidum hemagglutination (TPHA) tests became positive during hospitalization, and dark-field examination was positive for Treponemas, thus allowing the diagnosis of chancre of the rectum.
(2) Provided goats were immunized, it was found that the chancre reaction could be used to distinguish different populations of T. congolense.
(3) Local skin reactions (chancres) developed at the sites of inoculation with Trypanosoma evansi in rabbits and calves.
(4) Following the tsetse bite, the trypanosomes in the skin multiplied, reaching maximum numbers when the skin reaction (chancre) of the host attained its maximum size.
(5) In a preliminary study, two of four rabbits infected with human T-cell leukemia virus type I (HTLV-I) demonstrated prolonged primary chancres following superinfection with Treponema pallidum, the causative agent of syphilis.
(6) A chancre sore was infrequent in children; condylomata lata was the most frequent cutaneous lesion (80.9%).
(7) Clinically the patients with abnormal liquor developed multiple chancres, erosive papules, leukoderma, alopecia, neutrophilia; these patients had suffered from various diseases in the past.
(8) Certain types such as "chancre mou volant," however, could not be found in the present material.
(9) Expression of nine metacyclic variable antigen types (M-VATs) of Trypanosoma congolense in chancres from infected rabbits was determined using monoclonal antibodies raised against metacyclic forms of trypanosomes.
(10) After cutaneous inoculation of viable Treponema pallidum subsp pallidum into the skin of chancre-immune or previously uninfected rabbits, organisms move from perivascular connective tissue to localize extracellularly in hair follicles, erector pili muscles, and cutaneous nerves.
(11) The first symptom was a lesion, or chancre, in the genital region.
(12) A description is given of the structure of the basic cellular elements found in the chancres, particularly the plasma cells since it is in them that the main immunological processes take place.The morphology of the treponemes varies in the course of the pathological process as well as with the type of cell harbouring them.
(13) In calves, similar changes were observed although there were fewer trypanosomes present in the chancre and the cellular involvement was less extensive than that seen in the rabbit.
(14) In addition, HIV-infected rabbits demonstrate prolonged cutaneous lesions (chancres) after intracutaneous challenge with T. pallidum, the causative agent of syphilis.
(15) Sensitization and repetitive elicitation with P. acnes did not change the time of appearance or progression of syphilitic chancres after i.v or i.d.
(16) A clinical, bacteriological and serological pictures of 45 patients with chancriform pyoderma are presented, A single ulcer (92.8%), localized on genitals (91.1%) in adult males (93.3%), imitating or very similar to syphilitic primary chancre in our material was observed.
(17) A brief introduction on trypanosomiasis in ruminants and an explanation of the term chancre are followed by a discussion of a number of findings on the early pathogenesis of the disease.
(18) Local skin reactions (chancres) developed in goats at the sites of deposition, by tsetse flies, of metacyclics of Trypanosoma congolense.
(19) A case of primary tuberculous chancre of the vulva is reported.
(20) In long-standing chancres cyst-like formations with multi-layered membranes have been found.
Lesion
Definition:
(n.) A hurt; an injury.
(n.) Loss sustained from failure to fulfill a bargain or contract.
(n.) Any morbid change in the exercise of functions or the texture of organs.
Example Sentences:
(1) The telencephalic proliferative response has been studied in adult newts after lesion on the central nervous system.
(2) To quantify the size of the lesion in mice, the area of the infarct on the brain surface was assessed planimetrically 48 h after MCA occlusion by transcardial perfusion of carbon black.
(3) An effective graft-surveillance protocol needs to be applicable to all patients; practical in terms of time, effort, and cost; reliable; and able to detect, grade, and assess progression of lesions.
(4) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(5) Weddellite calcification was associated with benign lesions in 16 cases, but incidental atypical lobular hyperplasia and lobular carcinoma in situ were present, each in one case.
(6) One must be suspicious of any gingival lesion, particulary if there is a sudden onset of bleeding or hyperplasia.
(7) The cross sectional area of the aortic lumen was gradually decreased while the length of the stenotic lesion gradually increased by using strips with different width.
(8) A total of 555 caries lesions were registered on proximal surfaces, 49.1% being primary lesions in the enamel, 21.4% primary lesions into the dentin and 29.5% secondary lesions.
(9) Hypertensive disorders in pregnancy are frequently accompanied by deteriorated renal functions and by pathological lesions in the glomeruli.
(10) Pleural or subpleural lesions were found in all cases.
(11) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(12) The results also indicate that small lesions initially noted only on CT scans of the chest in children with Wilms' tumor frequently represent metastatic tumor.
(13) The lesion (10.6 X 9.8 mm) was a well-defined ellipsoid granuloma due to a foreign body with a central zone of necrosis surrounded entirely by a fibrous wall.
(14) Macroscopic lesions included mild congestion of the gastric mucosa and focal consolidation of the lung.
(15) Periosteal chondroma is an uncommon benign cartilagenous lesion, and its importance lies primarily in its characteristic radiographic and pathologic appearance which should be of assistance in the differential diagnosis of eccentric lesions of bones.
(16) We report on a patient, with a CT-verified low density lesion in the right parietal area, who exhibited not only deficits in left conceptual space, but also in reading, writing, and the production of speech.
(17) Differentiation between these two types of lesions is of utmost importance since the surgical approach will be different.
(18) In the upper limb and facial forms of familial amyloidotic polyneuropathy first recorded in Swiss and Finns respectively, the differences in their patterns of neurological disease and ocular lesions could be the result of their amyloids deriving from proteins other than prealbumin.
(19) In the present study, the expression of type IV collagen associated with the basal membrane (BM) was studied histochemically (indirect immunoperoxidase-antiperoxidase) in cervical human papillomavirus (HPV) lesions (diagnosed using in situ DNA hybridization) of different grades.
(20) Patients with sarcoidosis that present only cutaneous lesions are uncommon but have been described.