(v. t.) To alter; to make different; to cause to pass from one state to another; as, to change the position, character, or appearance of a thing; to change the countenance.
(v. t.) To alter by substituting something else for, or by giving up for something else; as, to change the clothes; to change one's occupation; to change one's intention.
(v. t.) To give and take reciprocally; to exchange; -- followed by with; as, to change place, or hats, or money, with another.
(v. t.) Specifically: To give, or receive, smaller denominations of money (technically called change) for; as, to change a gold coin or a bank bill.
(v. i.) To be altered; to undergo variation; as, men sometimes change for the better.
(v. i.) To pass from one phase to another; as, the moon changes to-morrow night.
(v. t.) Any variation or alteration; a passing from one state or form to another; as, a change of countenance; a change of habits or principles.
(v. t.) A succesion or substitution of one thing in the place of another; a difference; novelty; variety; as, a change of seasons.
(v. t.) A passing from one phase to another; as, a change of the moon.
(v. t.) Alteration in the order of a series; permutation.
(v. t.) That which makes a variety, or may be substituted for another.
(v. t.) Small money; the money by means of which the larger coins and bank bills are made available in small dealings; hence, the balance returned when payment is tendered by a coin or note exceeding the sum due.
(v. t.) A place where merchants and others meet to transact business; a building appropriated for mercantile transactions.
(v. t.) A public house; an alehouse.
(v. t.) Any order in which a number of bells are struck, other than that of the diatonic scale.
Example Sentences:
(1) Once treatment began, no significant changes occurred in Group 1, but both PRA and A2 rose significantly in Groups 2 and 3.
(2) Thirty-two patients (10 male, 22 female; age 37-82 years) undergoing maintenance haemodialysis or haemofiltration were studied by means of Holter device capable of simultaneously analysing rhythm and ST-changes in three leads.
(3) The assembly reaction is accompanied by characteristic changes in fluorescence emission and dichroic absorption.
(4) Although the mean values for all hemodynamic variables between the two placebo periods were minimally changed, the differences in individual patients were striking.
(5) It is concluded that during exposure to simulated microgravity early signs of osteoporosis occur in the tibial spongiosa and that changes in the spongy matter of tubular bones and vertebrae are similar and systemic.
(6) The various evocational changes appear to form sets of interconnected systems and this complex network seems to embody some plasticity since it has been possible to suppress experimentally some of the most universal evocational events or alter their temporal order without impairing evocation itself.
(7) A change in the pattern of care of children with IDDM, led to a pronounced decrease in hospital use by this patient group.
(8) The pattern of the stressor that causes a change in the pitch can be often identified only tentatively, if there is no additional information.
(9) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(10) Changes in cardiac adenosine triphosphate (ATP), phosphocreatine (PCr) and inorganic phosphate (Pi) were followed and intracellular pH (pHi) was estimated from the chemical shift of Pi.
(11) Subsequently, the study of bundle branch block and A-V block cases revealed that no explicit correlation existed between histopathological changes and functional disturbances nor between disturbances in conduction (i.e.
(12) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(13) As collapse was imminent, MAP increased but CO and TPR did not change significantly.
(14) Then a handful of organisers took a major bet on the power of people – calling for the largest climate change mobilisation in history to kick-start political momentum.
(15) Type 1 changes (decreased signal intensity on T1-weighted spin-echo images and increased signal intensity on T2-weighted images) were identified in 20 patients (4%) and type 2 (increased signal intensity on T1-weighted images and isointense or slightly increased signal intensity on T2-weighted images) in 77 patients (16%).
(16) No significant change occurred in the bacterial population of our hospital unit during the period of the study (more than 3 years).
(17) The availability and success of changes in reproductive technology should lead to a reappraisal of the indications for hysterectomy, especially in young women.
(18) The epidemiology of HIV infection among women and hence among children has progressively changed since the onset of the epidemic in Western countries.
(19) The present study examined whether the lack of chronic hemodynamic effects of ANP in control rats was due to changes in vascular reactivity to the peptide.
(20) The pancreatic changes are unlikely to be an artefact, but rather a direct toxic effect of the alcohol as confirmed by the biochemical changes.
Mutation
Definition:
(n.) Change; alteration, either in form or qualities.
Example Sentences:
(1) Neutrons induced a dose-dependent cytotoxicity and mutation frequency in the AL cells.
(2) The hprt T-cell cloning assay allows the detection of mutations occurring in vivo in the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene of T-lymphocytes.
(3) The pathology resulting from a missense mutation at residue 403 further suggests that a critical function of myosin is disrupted by this mutation.
(4) Mutational mosaicism was used as a developmental model to analyze 1,500 sporadic and 179 familial cases of retinoblastoma from the world literature.
(5) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(6) The results are consistent with our previous suggestion that lethality for virulent SFV infection results from a lethal threshold of damage to neurons in the CNS and that attenuating mutations may reduce neuronal damage below this threshold level.
(7) It is concluded that selection against insertional mutations is unlikely to be the major factor involved in the containment of element abundance.
(8) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
(9) The plasmid pMucAMucB, constructed from the Haemophilus influenzae vector pDM2, and a similar plasmid, constructed from pBR322, increased the survival after UV irradiation of Escherichia coli AB1157 with the umu-36 mutation and also caused UV-induced mutation in the E. coli strain.
(10) Peptidoglycan synthesis is unaffected by the mutations affecting the core glycosyltransferases.
(11) The v-erb A oncogene of avian erythroblastosis virus is a mutated and virally transduced copy of a host cell gene encoding a thyroid hormone receptor.
(12) Genetical analysis revealed that resistance to trimethoprim resulted from forward mutations at separate loci rather than back mutations of rad 6 or rad 18 alleles.
(13) Studies on asparagine synthetase indicate that resistance to albizziin may be due to altered regulation of asparagine synthetase, structural mutations of the enzyme, and gene amplification.
(14) Mice with mutations in four nonreceptor tyrosine kinase genes, fyn, src, yes, and abl, were used to study the role of these kinases in long-term potentiation (LTP) and in the relation of LTP to spatial learning and memory.
(15) The apparent sensitivity of Escherichia coli K12 to mild heat was increased by recA (def), recB and polA, but not by uvrA, uvrB or recF mutations.
(16) Tumorigenesis is a multistep process involving mutations of dominantly acting proto-oncogenes and mutations and loss-of-function mutations of tumor suppressor genes.
(17) Appropriate mutations in this pre-early gene allowed a productive infection in ColIb+ cells.
(18) Technically speaking, this modality of brief psychotherapy is based on the nonuse of transferential interpretations, on impeding the regression od the patient, on facilitating a cognitice-affective development of his conflicts and thus obtain an internal object mutation which allows the transformation of the "past" into true history, and the "present" into vital perspectives.
(19) Mutant alleles of rutabaga act in the germ line cells to partially suppress the developmental defects caused by dunce mutations.
(20) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.