(v. t.) To alter; to make different; to cause to pass from one state to another; as, to change the position, character, or appearance of a thing; to change the countenance.
(v. t.) To alter by substituting something else for, or by giving up for something else; as, to change the clothes; to change one's occupation; to change one's intention.
(v. t.) To give and take reciprocally; to exchange; -- followed by with; as, to change place, or hats, or money, with another.
(v. t.) Specifically: To give, or receive, smaller denominations of money (technically called change) for; as, to change a gold coin or a bank bill.
(v. i.) To be altered; to undergo variation; as, men sometimes change for the better.
(v. i.) To pass from one phase to another; as, the moon changes to-morrow night.
(v. t.) Any variation or alteration; a passing from one state or form to another; as, a change of countenance; a change of habits or principles.
(v. t.) A succesion or substitution of one thing in the place of another; a difference; novelty; variety; as, a change of seasons.
(v. t.) A passing from one phase to another; as, a change of the moon.
(v. t.) Alteration in the order of a series; permutation.
(v. t.) That which makes a variety, or may be substituted for another.
(v. t.) Small money; the money by means of which the larger coins and bank bills are made available in small dealings; hence, the balance returned when payment is tendered by a coin or note exceeding the sum due.
(v. t.) A place where merchants and others meet to transact business; a building appropriated for mercantile transactions.
(v. t.) A public house; an alehouse.
(v. t.) Any order in which a number of bells are struck, other than that of the diatonic scale.
Example Sentences:
(1) Once treatment began, no significant changes occurred in Group 1, but both PRA and A2 rose significantly in Groups 2 and 3.
(2) Thirty-two patients (10 male, 22 female; age 37-82 years) undergoing maintenance haemodialysis or haemofiltration were studied by means of Holter device capable of simultaneously analysing rhythm and ST-changes in three leads.
(3) The assembly reaction is accompanied by characteristic changes in fluorescence emission and dichroic absorption.
(4) Although the mean values for all hemodynamic variables between the two placebo periods were minimally changed, the differences in individual patients were striking.
(5) It is concluded that during exposure to simulated microgravity early signs of osteoporosis occur in the tibial spongiosa and that changes in the spongy matter of tubular bones and vertebrae are similar and systemic.
(6) The various evocational changes appear to form sets of interconnected systems and this complex network seems to embody some plasticity since it has been possible to suppress experimentally some of the most universal evocational events or alter their temporal order without impairing evocation itself.
(7) A change in the pattern of care of children with IDDM, led to a pronounced decrease in hospital use by this patient group.
(8) The pattern of the stressor that causes a change in the pitch can be often identified only tentatively, if there is no additional information.
(9) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(10) Changes in cardiac adenosine triphosphate (ATP), phosphocreatine (PCr) and inorganic phosphate (Pi) were followed and intracellular pH (pHi) was estimated from the chemical shift of Pi.
(11) Subsequently, the study of bundle branch block and A-V block cases revealed that no explicit correlation existed between histopathological changes and functional disturbances nor between disturbances in conduction (i.e.
(12) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(13) As collapse was imminent, MAP increased but CO and TPR did not change significantly.
(14) Then a handful of organisers took a major bet on the power of people – calling for the largest climate change mobilisation in history to kick-start political momentum.
(15) Type 1 changes (decreased signal intensity on T1-weighted spin-echo images and increased signal intensity on T2-weighted images) were identified in 20 patients (4%) and type 2 (increased signal intensity on T1-weighted images and isointense or slightly increased signal intensity on T2-weighted images) in 77 patients (16%).
(16) No significant change occurred in the bacterial population of our hospital unit during the period of the study (more than 3 years).
(17) The availability and success of changes in reproductive technology should lead to a reappraisal of the indications for hysterectomy, especially in young women.
(18) The epidemiology of HIV infection among women and hence among children has progressively changed since the onset of the epidemic in Western countries.
(19) The present study examined whether the lack of chronic hemodynamic effects of ANP in control rats was due to changes in vascular reactivity to the peptide.
(20) The pancreatic changes are unlikely to be an artefact, but rather a direct toxic effect of the alcohol as confirmed by the biochemical changes.
Perturbation
Definition:
(n.) The act of perturbing, or the state of being perturbed; esp., agitation of mind.
(n.) A disturbance in the regular elliptic or other motion of a heavenly body, produced by some force additional to that which causes its regular motion; as, the perturbations of the planets are caused by their attraction on each other.
Example Sentences:
(1) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(2) Ultraviolet difference spectrophotometry indicates that the inactivated enzyme retains its capacity for binding the nucleotide substrates whereas the spectral perturbation characteristic of 3-phosphoglycerate binding is abolished in the modified enzyme.
(3) It is suggested that laboratory experiments should be performed on perturbed systems only if simulations have shown that the methods of data analysis will be satisfactorily powerful and accurate.
(4) Thresholds were measured for detecting perturbations in a regular lattice of dots by modulating local dot density, local dot luminance, or some combination of the two.
(5) It is shown that when a constant current is applied such that a stable equilibrium and rhythmic firing are present, the following predictions are inherent in the HH system of equations: (a) Small instantaneous voltage perturbations to the axon given at points along its firing spike result in phase resetting curves (when new phase versus old phase is plotted) with an average slope of 1.
(6) Lower lip perturbation duration was manipulated to yield two different load conditions.
(7) The role of the Golgi complex in the post-translational oligosaccharide maturation of alpha-amylase was explored by use of the carboxylic ionophore, monensin (10(-7)M), a known perturbant of the structure and function of the Golgi complex.
(8) The importance of the ionic interaction due to the formation of the salt bridge between the Asp-27 and the pteridine ring in Escherichia coli dihydrofolate reductase-methotrexate complex has been studied by using the free-energy perturbation method.
(9) Presence of the monosynaptic reflex during platform perturbations at normal latencies suggests that balance problems in children with Down syndrome do not result from hypotonia, which researchers have defined as decreased segmental motoneuron pool excitability and pathology of stretch reflex mechanisms, but rather result from defects within higher level postural mechanisms.
(10) We have perturbed the dynamics of the nuclear lamins by means of cell fusion between mitotic and interphase cells and have studied redistribution of lamins in fused cells as a function of extracellular pH levels.
(11) In the coagulating gland, this compensatory response involved the proliferation of many cells which, in the absence of cytotoxic perturbation, would be non-proliferatie (Q cells).
(12) The effect of initial perturbation of the thrombus by a guide wire appears to be less important than the thrombus disruption and accelerated thrombolysis caused by the pulsatile delivery system.
(13) As before, subjects were instructed to either oppose the perturbation (Predictable Oppose) or relax the forearm muscles (Predictable Let-Go).
(14) Bivalent cations (Ca2+, UO2(2+) or Zn2+) in the subphase at pH 5.6 significantly modified the behaviour of mixed monolayers of fusogenic lipids with phospholipids; there was a parallel perturbing effect of fusogenic lipids on interactions between monolayers of phospholipids and bivalent cations.
(15) In particular, nitration of Tyr-51 provoked a structural perturbation in the globular region.
(16) Altering the biophysical characteristics of cell membranes by diet and membrane perturbing agents markedly influences thermosensitivity of cells.
(17) Paraphilias (PAs) and non-paraphilic sexual addictions (NPSAs) may be behaviors that share a common perturbation of central serotonin neuroregulation as a component of their pathophysiology.
(18) Two functions of these have been proposed: 1) that they are compatible osmolytes which regulate cell volume (against high external NaCl) without inhibiting proteins and 2) that methylamines (GPC and betaine) are counteracting osmolytes which stabilize proteins against perturbation from high renal urea.
(19) This high incidence of HER2 gene amplification with accompanying overexpression in non-invasive breast tumors suggests that perturbations of the HER2 oncogene are among the earliest and most common genetic lesions in human breast cancer.
(20) Hypophysectomy was selected as a model system for perturbing testicular cell types, since the cytological sequelae of this treatment post-hypophysectomy in the rat are well documented in the literature.