(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Chase
Definition:
(v. t.) To pursue for the purpose of killing or taking, as an enemy, or game; to hunt.
(v. t.) To follow as if to catch; to pursue; to compel to move on; to drive by following; to cause to fly; -- often with away or off; as, to chase the hens away.
(v. t.) To pursue eagerly, as hunters pursue game.
(v. i.) To give chase; to hunt; as, to chase around after a doctor.
(v.) Vehement pursuit for the purpose of killing or capturing, as of an enemy, or game; an earnest seeking after any object greatly desired; the act or habit of hunting; a hunt.
(v.) That which is pursued or hunted.
(v.) An open hunting ground to which game resorts, and which is private properly, thus differing from a forest, which is not private property, and from a park, which is inclosed. Sometimes written chace.
(v.) A division of the floor of a gallery, marked by a figure or otherwise; the spot where a ball falls, and between which and the dedans the adversary must drive his ball in order to gain a point.
(n.) A rectangular iron frame in which pages or columns of type are imposed.
(n.) The part of a cannon from the reenforce or the trunnions to the swell of the muzzle. See Cannon.
(n.) A groove, or channel, as in the face of a wall; a trench, as for the reception of drain tile.
(n.) A kind of joint by which an overlap joint is changed to a flush joint, by means of a gradually deepening rabbet, as at the ends of clinker-built boats.
(v. t.) To ornament (a surface of metal) by embossing, cutting away parts, and the like.
(v. t.) To cut, so as to make a screw thread.
Example Sentences:
(1) A man named Moreno Facebook Twitter Pinterest Italy's players give chase to an inscrutable Byron Moreno, whose relationship with the country was only just beginning.
(2) Results obtained from cumulative labeling and pulse-labeling and chase experiments with cells from late gastrulae, yolk plug-stage embryos, and neurulae showed that the 30S RNA is an intermediate in rRNA processing and is derived from 40S pre-rRNA and processed to 28S rRNA.
(3) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(4) Evidence of the industrial panic surfaced at Digital Britain when Sly Bailey, the chief executive of Trinity Mirror, suggested that national newspaper websites that chased big online audiences have "devalued news" , whatever that might mean.
(5) All 17 candidates are going to be participating in debate night and I think that’s a wonderful opportunity Reince Priebus Republican party officials have defended the decision to limit participation, pointing out that the chasing pack will get a chance to debate separately before the main event.
(6) Pulse-chase experiments showed that the ornithine transcarbamylase precursor and the thiolase traveled from the cytosol to the mitochondria with half-lives of less than 5 min, whereas the three fusion proteins traveled with half-lives of 10-15 min.
(7) Mark Latham's insights, insults and feuds are why he's worth reading | Gay Alcorn Read more BuzzFeed political editor Mark Di Stefano, the reporter who broke the story linking Latham to the less-than-savoury @RealMarkLatham Twitter account , had been chasing Stutchbury for days.
(8) So the government wants a “root and branch” review to decide whether the BBC has “been chasing mass ratings at the expense of its original public service brief” ( BBC faces ‘root and branch’ review of its size and remit , 13 July).
(9) Pulse-chase analysis of the labelling of these lipids indicates that PI and lysoPI rapidly equilibrate after the initial slow synthesis of PI.
(10) The report's authors warns that to limit their spending councils will have "an incentive to discourage low-income families from living in the area" and that raises the possibility that councils will – like the ill-fated poll tax of the early 1990s – be left to chase desperately poor people through the courts for small amounts of unpaid tax.
(11) This result indicates that part of 5'-nucleotidase keeps one or two high-mannose or hybrid chains in the mature form, even after prolonged pulse-chase labeling.
(12) Conroy, out at the ovarian cancer event we’ve already touched on, was unrepentent as he was chased down the corridor by reporters.
(13) "For tax evaders, she should turn to Pasok and New Democracy to explain to her why they haven't touched the big money and have been chasing the simple worker for two years."
(14) Surfers chase the reliable swell here when it's flat further west.
(15) The mature molecular mass form of each of these proteins reaches its maximum specific radioactivity in a purified hepatocyte plasma membrane fraction after only 45 min of chase.
(16) In pulse-chase experiments, labelled proteins 26-34 kDa, appeared within 10 min and smaller forms co-migrated with surfactant-associated glycoprotein A from alveolar lavage.
(17) As a consequence of chasing funding, organisations shift their focus away from their areas of expertise into where the money is to sustain themselves.
(18) The secretion kinetics of nine proteins by Hep G2 cells in culture was investigated using pulse-chase techniques and immunoisolation of proteins with monospecific antibodies.
(19) Pulse-chase and long-term labeling experiments revealed different half-lives for the two c-myc-encoded proteins.
(20) It's an anxious time for those 180,000 teenagers chasing the last university places in clearing ; nails are bitten to the quick, eyes glazed from internet searching.