(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Fuller
Definition:
(v. t.) One whose occupation is to full cloth.
(a.) A die; a half-round set hammer, used for forming grooves and spreading iron; -- called also a creaser.
(v. t.) To form a groove or channel in, by a fuller or set hammer; as, to fuller a bayonet.
Example Sentences:
(1) The results indicated that neuropsychological measures may serve to broaden the concept of intelligence and that a brain-related criterion may contribute to a fuller understanding of its nature.
(2) Matthew Fuller, 25, Rueben Barnes, 16, and Mitchell Sweeney, 22, died from electrocution and Marcus Wilson, 19, died after installing insulation batts in extreme heat.
(3) First in line was Conservative Richard Fuller, who he believed was looking at him in a funny way.
(4) The initiative, co-ordinated by the chairman of sportswear brand Skins, Jaimie Fuller, was also backed by Tory MP Damian Collins.
(5) The combination of T7 RNA polymerase, T7 DNA polymerase, and T7 gene 4 protein initiates DNA synthesis in vitro within the cloned origin sequence (Fuller, C. W., and Richardson, C. C. (1985) J. Biol.
(6) In an open letter to the college Fran Fuller, chair of BASW, says that the plans were a surprise, as the organisations have a memorandum of understanding in place and have spent "many weeks" positively discussing the college's development.
(7) "Sir Jeremy could and should have advised the prime minister to refer the allegations of ministerial misconduct to the prime minister's adviser for a fuller investigation.
(8) In addition, because a firm understanding of basic laser-tissue interactions is key to knowledgeably and sensibly using lasers, regardless of the delivery mode, we present an overview of some basic principles; readers interested in a greater level of detail should consult other sources for a fuller understanding of the issues.
(9) If the CMA goes ahead with a preliminary investigation it will have 40 working days to clear the deal, seek remedies or move to a fuller inquiry that could take six months.
(10) Fuller's XIX Entertainment, pointedly thanked by the player on Thursday, was responsible for creating "Brand Beckham" and a string of global marketing deals.
(11) NSW police announce first bomb amnesty – but just don't bring them in Read more Fuller said there was a “new phenomenon” of people who may be at risk of committing violent acts that did not fit into the traditional profile police had established of potential terrorism suspects.
(12) As a charity that campaigns on issues of women’s economic equality, we take these allegations extremely seriously and will do our utmost to investigate them … we remain confident that we took every practicable and reasonable step to ensure that the range would be ethically produced and await a fuller understanding of the circumstances under which the garments were produced.” When the Fawcett Society sought reassurance about standards at the factory, Whistles emailed back to say CMT is “a fully audited, socially and ethical compliant factory” and cited accreditations relating to the provenance and content of materials.
(13) A separate proposal suggested that companies provide "fuller information on the relationship between pay and company performance".
(14) An important key to the resolution of these debates lies in attaining a fuller understanding of the morphological differences in skull form between the African and Asian great apes.
(15) Four men died while installing home insulation – Matthew Fuller, Reuben Barnes, Mitchell Sweeney and Marcus Wilson.
(16) Fuller claimed that The X Factor has stolen parts of the Pop Idol format and took legal action.
(17) Trustees are appealing for more information, pictures and stories from veterans or their relatives to paint a fuller picture of life at Bletchley Park, where 20 years of campaigning for recognition of its importance, plus restoration and developments have turned it into a tourist attraction.
(18) The result suggest that higher response rates may be achieved in studies of cancer if fuller disclosure of the study purposes is made.
(19) It was entirely characteristic of Ross that 15 years later, when he had virtually given up book-publishing, he should have revived the LME imprint to produce two hardbacks by his old and abruptly publisherless friend Roy Fuller, and made a great success of them.
(20) 1977a: Fink, 1986: Fishb ein & Griffin, 1976: Fujikawa, 1981: Fuller & De Loecker, 1985: Lazarus et al.