(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Gouge
Definition:
(n.) A chisel, with a hollow or semicylindrical blade, for scooping or cutting holes, channels, or grooves, in wood, stone, etc.; a similar instrument, with curved edge, for turning wood.
(n.) A bookbinder's tool for blind tooling or gilding, having a face which forms a curve.
(n.) An incising tool which cuts forms or blanks for gloves, envelopes, etc. from leather, paper, etc.
(n.) Soft material lying between the wall of a vein aud the solid vein.
(n.) The act of scooping out with a gouge, or as with a gouge; a groove or cavity scooped out, as with a gouge.
(n.) Imposition; cheat; fraud; also, an impostor; a cheat; a trickish person.
Example Sentences:
(1) John, who has just been released from prison on licence after serving four years for gouging a man’s eye out , admits: “I used to see Tyson on the television.
(2) Democratic presidential candidates Hillary Clinton and Bernie Sanders have accused Turing of price-gouging.
(3) There was a deep gouge across the back of his head and blood was welling through his copper- coloured hair.
(4) Make a hole in the radius with a small gouge with insertion of the pin to the fracture site and then drive it into the proximal fragment.
(5) How it gouges money from those who don’t own only to put it in the pockets of those who do.
(6) The following technical devices have been adopted: -- curved unilateral incision into deep fascia --interlaminar space widening by chisels and gouges, avoiding the use of rongeurs -- sodium succinate methylprednisolone injection into dural sac.
(7) "I bought her, and I still can't believe this, I might as well have gouged out my own eyeballs with a rusty spoon, but I bought her a personalised number plate which was M155 LTD. Miss Living The Dream.
(8) The crumpled metal cockpit floor featured large gouges.
(9) Olympe de Gouges, born in 1748, led in Paris, the brilliant and dissolute life of a rather mediocre writer and a passionate feminist, demanding for women the right to go into politics.
(10) Their white tents stood near the brown earth gouged by the armoured trucks that had carried them there – the closest point to Mosul they had reached before an assault on Iraq’s second largest city.
(11) Topology favoring attachment was inherent in 0.45-mum filters and was produced in plastic by gouging irregular excavations 10 to 15 micrometer deep.
(12) Karen McVeigh Governor Christie (@GovChristie) We have activated temporary hotlines to report price gouging.
(13) Greedy, gouging bastards, depriving students of their last few pennies in a relentless quest for profit.
(14) Yemen's humanitarian crisis leaves a million people in dire straits – in pictures Read more Maurer, who recently visited Yemen and Iran to negotiate broader humanitarian access, said air raids had gouged craters in the streets of the Yemeni capital Sana’a.
(15) Crash patterns-such as cut and damaged vegetation, gouges, debris scatter, burn areas, etc.,-and their spatial relations can be very effectively evaluated by the analysis of stereo aerial photographs.
(16) He has people eating their sons in pies, men with their eyes gouged out, and merciless sexual jealousy.
(17) With a chisel or a gouge, cuts are made in the cortical surface of the bone on both sides of the fracture line, and numerous scales are lifted but remain attached at the base, like the petals of a flower.
(18) In what will come as welcome news to defenders across the land, chippy Chelsea striker Diego Costa may also be leaving these shores to gouge, elbow, snarl and kick his way around his old La Liga stamping ground.
(19) The worst of the episodes involved Mousa Dembélé, who gouged at Diego Costa’s eyes during a wider mêlée sparked by a confrontation between Danny Rose and Willian.
(20) ); (2) exploitation of bark surface insects and the use of trunks as a platform to locate terrestrial prey (Saguinus fuscicollis, S. nigricollis, and Callimico); (3) manipulative foraging and bark stripping to locate concealed insects and small vertebrates (Leontopithecus); and (4) tree gouging and year-round exudate feeding (many Callithrix).