(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Grip
Definition:
(n.) The griffin.
(n.) A small ditch or furrow.
(v. t.) To trench; to drain.
(v. t.) An energetic or tenacious grasp; a holding fast; strength in grasping.
(v. t.) A peculiar mode of clasping the hand, by which members of a secret association recognize or greet, one another; as, a masonic grip.
(v. t.) That by which anything is grasped; a handle or gripe; as, the grip of a sword.
(v. t.) A device for grasping or holding fast to something.
(v. t.) To give a grip to; to grasp; to gripe.
Example Sentences:
(1) The sound of the ambulance frightened us, especially us children, and panic gripped the entire community: people believe that whoever is taken into the ambulance to the hospital will die – you so often don’t see them again.
(2) It’s as though the nation is in the grip of an hysteria that would make Joseph McCarthy proud.
(3) The single best predictor of EI was BW (r2 = 0.47, p = 0.0001), and further small but significant contributions were made by BMC (r2 = 0.53, p = 0.0001) and grip strength (r2 = 0.55, p = 0.0001).
(4) However, it had no significant effect on grip strength, digital contractures, respiratory function or visceral involvement.
(5) Indian women are aware of our tenuous grip on our rights.
(6) The recovery of power grip and finger grip strength is complete in most patients by two months.
(7) Results indicate substantial postoperative improvement in tip prehension and grasp, while performance remained essentially unchanged for lateral prehension, pinch force, and power grip.
(8) Mean grip strength and grip strength per kilogram weight are presented for age 59, ages 60-64 and 65-69.
(9) The measurement is used to control a sensory feedback device applied to the surface of the skin within the socket of the prosthesis informing the wearer of the strength of grip exerted.
(10) Plasma catecholamine levels and the haemodynamic response to the hand-grip test have therefore been evaluated in a group of young athletes, compared with a group of non-trained youths.
(11) The Guardian's Xan Brooks described Fruitvale Station as a "quietly gripping debut feature" in which "one has the sense of a man being slowly, surely written back into being" after the film's Cannes screening in May.
(12) What the film does, though, is use these incidents to build an idiosyncratic but insightful picture of Lawrence, played indelibly by Peter O'Toole in his debut role: a complicated, egomaniacal and physically masochistic man, at once god-like and all too flawed, with a tenuous grip both on reality and on sanity.
(13) Heart rate elevation observed after hand grip maneuver did not change.
(14) That's why the policies that are desperately needed for the majority to break the grip of a failed economic model would also help make regulated migration work for all: stronger trade unions, a higher minimum wage, a shift from state-subsidised low pay to a living wage, a crash housing investment programme, a halt to cuts in public services, and an end to the outsourced race to the bottom in employment conditions.
(15) Once I’d checked she was OK I said, ‘Stop crying now.’ ” So it’s about managing emotions: ‘I’m going to need you to get a grip.’” “If you’ve got interesting points to make about the devaluing of serious words like bullying and depression, why make them in a way that sounds like you’re ridiculing people who are suffering?” I ask.
(16) "Zidane, Zidane, Zidane... France was in the grip of 'zizoumania'," Marcel Desailly wrote in his autobiography, reflecting on the triumph on home soil eight years ago, when giant images of the No 10 covered the sides of floodlit office blocks.
(17) The Holland manager had decided to retain the 5-3-2 system that worked so effectively against Spain but he reverted to 4-3-3 at the interval after losing Martins Indi and accepting that something had to change to enable his players to get a grip on a game that Australia were controlling in the first half.
(18) Loss of the righting response was not associated with any gross reduction in skeletal muscle tone (inclined screen and wire grip tests) and it was proposed that the animals were not anaesthetized but instead could be placed on their backs because flurazepam had enhanced the cataleptic effect of THC.
(19) The blood flow through the forearm was measured 2 sec after single, brief isometric hand-grip contractions.
(20) Analysis of the rate of functional recovery as measured by total active motion, gross grip strength, and pinch grip strength showed no significant difference between the two groups.