(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Lane
Definition:
(a.) Alone.
(n.) A passageway between fences or hedges which is not traveled as a highroad; an alley between buildings; a narrow way among trees, rocks, and other natural obstructions; hence, in a general sense, a narrow passageway; as, a lane between lines of men, or through a field of ice.
Example Sentences:
(1) Tottenham Hotspur’s £400m redevelopment of White Hart Lane could include a retractable grass pitch as the club explores the possibility of hosting a new NFL franchise.
(2) These lanes encourage cyclists to 'ride in the gutter' which in itself is a very dangerous riding position – especially on busy congested roads as it places the cyclist right in a motorist's blind spot.
(3) A two-lane, 400m bridge – funded by Jica, Japan's aid agency – coupled with simplified procedures agreed by Zambia and Zimbabwe have speeded up processing time.
(4) Cluster analysis results could not be considered valid, since replicate lanes in different gels were not grouped together.
(5) The deal will be effective from 28 February, meaning Defoe has the opportunity to add to his 142 goals for the White Hart Lane club.
(6) "I'm led to believe that Notts County used to play their home games at Trent Bridge, The Oval hosted an FA Cup final and Bramall Lane used to be a cricket ground, but are there any other cricket grounds that have hosted either league or international football matches?"
(7) "A typical day in London would be: wake up hungover, try to get some breakfast in you," he says, barrelling along green-tunnelled country lanes through – as he puts it in Jerusalem – the "wild garlic and May blossom" that mean winter is over.
(8) When I had that keyhole surgery, I thought: ‘Maybe, if I come back, it won’t be to that top level.’ But with the support I have been getting from my coach, family and friends, I think that really motivated me to come back strong.” Kenya is more famed for its distance runners and steeplechasers than its hurdlers, but the country was left celebrating a surprise gold medal in the 400m hurdles when Nicholas Bett powered home from lane nine to smash his personal best to win in 47.79sec.
(9) Lanes and bands can be added or removed, based upon users' subjective preferences.
(10) We replicated DNA fingerprints of snapping turtles (Chelydra serpentina) and hypervariable restriction fragments of red-winged blackbirds (Agelaius phoeniceus) to estimate the between-blot and between-lane components of variance in molecular weights of restriction fragments.
(11) At peak times 1,300 vehicles an hour will use the lanes, with non-Olympic motorists fined £130 if they stray into them.
(12) Riga, accompanied by Fraeye, was at Charlton's Sparrows Lane training ground on Tuesday and watched on as Powell's existing coaching staff oversaw the first-team squad.
(13) If the orienting voltage was applied parallel to the direction of electrophoresis, both linear and supercoiled DNA molecules migrated in straight lanes.
(14) The technology is also there for green-laning, says Everett – intelligent traffic lights that recognise where traffic is coming from, allowing cars to flow more freely and cutting down on unnecessary braking and restarting, which wastes energy.
(15) On the other hand, the relatively smooth-surfaced 'lanes' between groups of respiratory islets have a microridged surface similar to that of the primary gill lamellae.
(16) There are nominal cycle lanes on some of the capital's main thoroughfares, but with seven million cars jostling for space, those lanes are often cannibalised by motorised rickshaws and scooters, leaving no safe space for bicyclists.
(17) However, it is early days for Pochettino’s side and Tottenham’s credentials will be fully tested by Liverpool, whose 5-0 victory at White Hart Lane last season led to André Villas-Boas losing his job.
(18) Monkey chants rang out at White Hart Lane this month as visiting Lazio "Ultras" from Italy abused three Spurs players.
(19) Obama came out firmly against “fast” and “slow” lanes arguing against cable firm’s charging higher fees for faster service.
(20) The lanes were discussed at the first of a series of daily meetings, chaired on Monday by David Cameron , which assessed security and transport arrangements for the Olympics.