(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Meander
Definition:
(n.) A winding, crooked, or involved course; as, the meanders of the veins and arteries.
(n.) A tortuous or intricate movement.
(n.) Fretwork. See Fret.
(v. t.) To wind, turn, or twist; to make flexuous.
(v. i.) To wind or turn in a course or passage; to be intricate.
Example Sentences:
(1) They harvest shellfish standing in the water or meandering through mangrove forests on the shore.
(2) BMWs, Porsches and Land Cruisers meander through Luanda past beggars missing limbs due to the civil war or polio.
(3) As the contest meandered and the stadium went close to quiet there was a jocular moment when Pardew hopped in irritation at a United challenge and the manager dropped his ever-present notebook on the pitch.
(4) This packing loosens towards the middle of the junction until, at its basal extremity, the septa (ridges in replicas) are widely separated and follow independent meandering courses.
(5) The result is a meandering popularism that ignores questions about where the country might end up and fixates on the most cynical of political games.
(6) • Rorbu for four from £140 a night, svinoya.no Grande Hytteutleige, Geirangerfjord Facebook Twitter Pinterest Waterfalls, vertiginous green slopes and a meandering, idyllic waterway explain why Unesco-protected Geirangerfjord is one of Norway’s premier tourist spots.
(7) A drifter, he meandered from city to city, in and out of prison, before arriving in Paradise, where he founded the first branch of the Allah Temple Of Islam in 1930 and set himself up as a black Messiah.
(8) I wanted to write a book that was big and odd and meandering, and I did and it was.
(9) Subtractive feedback models must continuously adjust the axis of rotation throughout a saccade, and they generate meandering, dysmetric gaze saccades.
(10) He had already come close when, gifted the chance by a weak Julian Speroni punch, he lofted a shot into the unguarded net towards the end of a first 45 minutes that had tended to meander.
(11) They meticulously slotted together details to give a painstaking picture of the events that led up to the girls' disappearance, and then away from it; the innocent before and the nightmarish after; the last known seconds of the girls' meandering progress through familiar streets, arms linked, and then the frantic, increasingly heart-rending search that came to an end when the naked and decomposing - and, as we now know, partially burned - bodies of the two friends were found lying together, limbs tangled, at the bottom of a deep and muddy ditch, where the nettles grew tall.
(12) Some meandering evaginations were also observed as, rarely, were small spherical or bulbous projections.
(13) The similarity in size of the openings of T tubules and caveolae and the meandering path of the tubules are sufficient to account for the paucity of observed openings.
(14) The cytoskeleton, marked by antibodies to desmin and filamin is composed of a mainly longitudinal, meandering and branched system of fibrils that contrasts with the plait-like, interdigitating arrangement of linear fibrils of the contractile apparatus, labeled with antibodies to myosin and tropomyosin.
(15) From here the contest meandered for a while on a Shanghai night becoming ever more sultry.
(16) After a deliberately hazy and meandering first half – one that lulls both reader and characters into a false sense of security – the second part of the novel barely breathes.
(17) London 2012 chairman Lord Coe, who has spent the week defending his organisation against blame for the G4S meltdown, said he believed that while the torch meandered through London it would stoke enthusiasm as it had among the millions who have seen it criss-cross the country over the past 63 days.
(18) Inspired by the idea of a city built around an airport (she grew up in Hounslow, near Heathrow), it leaves behind the constraints of any one genre, meandering through R&B-inflected garage (Beach Mode), instrumental grime (Backhand Winners) and Omar S-style stripped-back melodic techno (Eternal Mode).
(19) The endoplasmic reticulum in such cells is reduced to a few (perhaps only one) meandering, broad cisternae, which delimit broad fields of cytoplasmic matrix occupied almost solely by scattered, single ribosomes.
(20) As the match threatened to meander away from United, Giggs finally introduced Van Persie, for a first appearance due to a knee injury since 19 March, and Welbeck, on 66 minutes.