(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Navigable
Definition:
(a.) Capable of being navigated; deep enough and wide enough to afford passage to vessels; as, a navigable river.
Example Sentences:
(1) BigDog Facebook Twitter Pinterest BigDog is a autonomous packhorse Funded by Darpa and the US army, BigDog is Boston Dynamics’ most famous robot, a large mule-like quadruped that walks around like a dog, self balancing and navigating a range of terrain.
(2) An error and covariances analysis shows that the method is robust and accurate enough for autonomous navigation.
(3) "GNH is an aspiration, a set of guiding principles through which we are navigating our path towards a sustainable and equitable society.
(4) Since the introduction of universal credit we’ve made sure staff know how to support customers navigating the new claim system.
(5) It is clear that different subsets of navigational cues guide sensory afferents to muscle and to cutaneous destinations.
(6) But US security experts criticised the administration for appearing to time its intervention to suit conflicting agendas of the Asean and Paris summits rather than more boldly assert the principle of freedom of navigation.
(7) Instead it said that the changing of the settings – which previously required users to navigate through up to 150 different settings to control who could see their data, to a simpler four-tiered version plus a "customise" option – was "merely a red herring".
(8) Further, the results identify the hippocampus as a structure critical for the regulation of navigational behavior that manifests itself in a natural setting.
(9) Right parietal lesions resulted in deficits in both tasks, but especially landmark navigation.
(10) Daballen navigates the jeep between thorn bushes and over furrows, guided by a rising moon and his intimate knowledge of the terrain.
(11) Lord Freud revealed his futuristic vision of how people could soon claim benefits, suggesting ultimately claimants might take advantage of the development of internet eye-glasses by Google – which allows users to surf the internet on the lens of a pair of glasses, using eye movement to navigate the web and make benefits claims.
(12) The thinktank added: “It will be interesting to watch next week how Mr Osborne navigates these treacherous waters and avoids the obstacles he constructed for himself.
(13) It's only when you try to navigate the system for an elderly relative that you realise how an older person's wellbeing and resilience matter less than the place in the NHS hierarchy of the hospital consultant, GP and social worker.
(14) From its earliest days, Facebook has navigated – even pioneered – the territory around privacy, and how we express our personal identities online.
(15) We are considering how to demonstrate freedom of navigation in an area that is critical to world trade,” a US official said, speaking on condition of anonymity.
(16) Our findings are consistent with the hypothesis that navigating axons may respond to multiple guidance cues during development.
(17) Despite Trump’s enthusiasm for Kushner, he will have to navigate a US anti-nepotism law that states a public official “may not appoint, employ, promote, advance, or advocate for appointment … any individual who is a relative of the public official”.
(18) But I also know, from my own family’s navigation of a shocking event, that there can be the inverse response as well.
(19) The rats also showed good acquisition of escape response in a water maze task carried out 13 weeks after ischemia, but showed slight impairment of spatial navigation in the transfer test.
(20) This mode of navigation can be modeled as an input control process that selectively retains favorable and rejects unfavorable consequences of the random responses.