(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Pipe
Definition:
(n.) A wind instrument of music, consisting of a tube or tubes of straw, reed, wood, or metal; any tube which produces musical sounds; as, a shepherd's pipe; the pipe of an organ.
(n.) Any long tube or hollow body of wood, metal, earthenware, or the like: especially, one used as a conductor of water, steam, gas, etc.
(n.) A small bowl with a hollow steam, -- used in smoking tobacco, and, sometimes, other substances.
(n.) A passageway for the air in speaking and breathing; the windpipe, or one of its divisions.
(n.) The key or sound of the voice.
(n.) The peeping whistle, call, or note of a bird.
(n.) The bagpipe; as, the pipes of Lucknow.
(n.) An elongated body or vein of ore.
(n.) A roll formerly used in the English exchequer, otherwise called the Great Roll, on which were taken down the accounts of debts to the king; -- so called because put together like a pipe.
(n.) A boatswain's whistle, used to call the crew to their duties; also, the sound of it.
(n.) A cask usually containing two hogsheads, or 126 wine gallons; also, the quantity which it contains.
(v. i.) To play on a pipe, fife, flute, or other tubular wind instrument of music.
(v. i.) To call, convey orders, etc., by means of signals on a pipe or whistle carried by a boatswain.
(v. i.) To emit or have a shrill sound like that of a pipe; to whistle.
(v. i.) To become hollow in the process of solodifying; -- said of an ingot, as of steel.
(v. t.) To perform, as a tune, by playing on a pipe, flute, fife, etc.; to utter in the shrill tone of a pipe.
(v. t.) To call or direct, as a crew, by the boatswain's whistle.
(v. t.) To furnish or equip with pipes; as, to pipe an engine, or a building.
Example Sentences:
(1) The Hamilton-Wentworth regional health department was asked by one of its municipalities to determine whether the present water supply and sewage disposal methods used in a community without piped water and regional sewage disposal posed a threat to the health of its residents.
(2) We ganged up against the tweed-suited, pipe-smoking brigade.
(3) A reduction of salmonellae during the passage of the pump and pressure conduit-pipe, combining east- and west-side of Kiel fjord, could be seen.
(4) His next target, apart from the straightforward matter of retaining his champion's title this winter, is 4,182, being the number of winners trained by Martin Pipe, with whom he had seven highly productive years at the start of his career.
(5) In an emergency, the devices use multiple mechanisms – including clamps and shears – to try to choke off the oil flowing up from a pipe and disconnect the rig from the well.
(6) However, a homemade pipe bomb thrown at a police patrol in north Belfast earlier this year was described as of a new, sophisticated variety that the PSNI had not seen before.
(7) In 1967-1969 survey the ratio of observed to expected concordance for smoking was higher among the monozygotic twins than among the dizygotic twins for those who had never smoked (overall rate ratio, 1.38; 95 percent confidence interval, 1.25 to 1.54), for former smokers (overall rate ratio, 1.59; 95 percent confidence interval, 1.35 to 1.85), for current cigarette smokers (overall rate ratio, 1.18; 95 percent confidence interval, 1.11 to 1.26), and for current cigar or pipe smokers (overall rate ratio, 1.60; 95 percent confidence interval, 1.22 to 2.06).
(8) After visiting the H-blocks, the Catholic archbishop Cardinal Tomás Ó Fiaich compared the conditions to "the sewer pipes in the slums of Calcutta".
(9) Vibratome sectons are incubated at 37 degrees C for 60 min in 0.1 M Pipes buffer, pH 7.8, containing 3 mM cerium chloride and 0.1 mM sodium urate.
(10) Women smokers, cigar, and pipe smokers also face an increased risk for lung cancer.
(11) While studying forced inhale the diaphragms were set up at Fleish pipe airflow input.
(12) In addition, the risk of lung cancer associated with other methods of tobacco consumption--in particular, the use of bamboo water-pipes and long-stem pipes--is uncertain.
(13) Escherichia coli, Citrobacter freundii and Klebsiella pneumoniae grew after the experimental contamination for many weeks on the rubber hose until the test was finally stopped, in the other pipes and hoses (glass, high-grade steel, PVC, PE, PA, PTFE and silicone) E. coli could be found for maximal 7 weeks, Citrobacter freundii for 1 week and Klebsiella pneumoniae for maximal 3 weeks.
(14) Building CHP stations near industrial sites means that the heat can be piped into factories or buildings as high pressure steam or hot water.
(15) The in vitro binding properties of 1-(cyclopropylmethyl)-4-(2'-(4''-fluorophenyl)-2'-oxoethyl)pipe ridi ne HBr, [3H]DuP 734, a novel sigma receptor ligand, were examined in homogenates of guinea pig brain.
(16) Social changes going on in the society were reflected in choice of substance forms by younger people as compared to their elders (e.g., cigarettes vs pipes or cigars, heroin vs opium, manufactured vs village-produced alcohol).
(17) The reaction of an unspecific microorganism flora and of Legionella pneumophila in pipes and hoses has been described in the two previous communications.
(18) One company will effectively control the only data pipe going into a near majority of American homes, whether that’s internet TV or phones,” Stoltz said.
(19) Radical species are formed from the piperazine ring-based buffers Hepes (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Epps 4-(2-hydroxyethyl)-1-piperazinepropanesulfonic acid, and Pipes 1,4-piperazinediethanesulfonic acid, but not from Mes (4-morpholineethanesulfonic acid) which contains a morpholine ring.
(20) "Two guys came and spent several hours tracking down the cause, which turned out to be a blocked pipe.