(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Programme
Definition:
(n.) That which is written or printed as a public notice or advertisement; a scheme; a prospectus; especially, a brief outline or explanation of the order to be pursued, or the subjects embraced, in any public exercise, performance, or entertainment; a preliminary sketch.
Example Sentences:
(1) Squadron Leader Kevin Harris, commander of the Merlins at Camp Bastion, the main British base in Helmand, praised the crews, adding: "The Merlins will undergo an extensive programme of maintenance and cleaning before being packed up, ensuring they return to the UK in good order."
(2) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(3) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
(4) A programme is described in which indigenous personnel are trained to provide culturally appropriate rehabilitation services for islanders of the Pacific Basin.
(5) A study was conducted to determine the usefulness of self-screening of blood pressure in families as part of a school health care programme, and to study the relationship between BP and sodium excretion in school children.
(6) This investigation examined the extent to which attitudes of doctors who participated in a one-year training programme for general practice changed in intended directions by training.
(7) Channel 4 News said on Friday that Manji and the programme’s producer, ITN, had made an official complaint to press regulator Ipso.
(8) We repeat our call for them to do so at the earliest opportunity, and to share those findings so that we can take any appropriate actions.” In the BBC programme the 29-year-old Rupp, who won 10,000m silver at the London 2012 Olympics behind Farah, was accused of having taken testosterone and being a regular user of the asthma drug prednisone, which is banned in competition.
(9) Ninety semen specimens were analysed for use in an IVF-embryo transfer (ET) programme.
(10) Compared to the SRK II-equation the results of the new programme are much more precise.
(11) The data of first 1000 first-born, non-malformed, mature (greater than or equal to 2500 g) offspring of participants in the Hungarian "Optimal" Family Planning Programme were evaluated.
(12) However, its possible value in such programmes has not been proven here.
(13) Estonia had been reduced to 10 men early in the second half yet Hodgson’s men had to toil away for another 25 minutes before the goal, direct from Wayne Rooney’s free-kick, that soothed their mood and maintained their immaculate start to this qualifying programme.
(14) This empirical fact has in recent years been increasingly dealt with in pertinent German-language literature, the discussion clearly emphasizing the demand that programmes aimed at the vocational qualification of unemployed disabled persons be provided, along with accompanying measures.
(15) The Disability Division of ActionAid-India supports 38 non-governmental organisations involved in disability programmes in India.
(16) As a strategy to reach hungry schoolchildren, and increase domestic food production, household incomes and food security in deprived communities, the GSFP has become a very popular programme with the Ghanaian public, and enjoys solid commitment from the government.
(17) The authors are also upfront about what has not gone so well: "We were too slow to mobilise … we did not identify clear leadership or adequate resources for the actions … it is vital to accelerate the programme of civil service reform."
(18) This may have been a pointed substitute programme, management perhaps imagining a future where electronic presenters will simply download their minds to MP3-players.
(19) Guy Jobbins, a Cairo-based British water scientist who heads Canada's International Development Research Centre climate change adaptation programme for Africa, says understanding of the issue has rocketed in the past few years.
(20) He has also been a vocal opponent of gay marriage, appearing on the Today programme in the run-up to the same-sex marriage bill to warn that it would "cause confusion" – and asking in a Spectator column, after it was passed, "if the law will eventually be changed to allow one to marry one's dog".