(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Straight
Definition:
(a.) A variant of Strait, a.
(superl.) Right, in a mathematical sense; passing from one point to another by the nearest course; direct; not deviating or crooked; as, a straight line or course; a straight piece of timber.
(superl.) Approximately straight; not much curved; as, straight ribs are such as pass from the base of a leaf to the apex, with a small curve.
(superl.) Composed of cards which constitute a regular sequence, as the ace, king, queen, jack, and ten-spot; as, a straight hand; a straight flush.
(superl.) Conforming to justice and rectitude; not deviating from truth or fairness; upright; as, straight dealing.
(superl.) Unmixed; undiluted; as, to take liquor straight.
(superl.) Making no exceptions or deviations in one's support of the organization and candidates of a political party; as, a straight Republican; a straight Democrat; also, containing the names of all the regularly nominated candidates of a party and no others; as, a straight ballot.
(adv.) In a straight manner; directly; rightly; forthwith; immediately; as, the arrow went straight to the mark.
(n.) A hand of five cards in consecutive order as to value; a sequence. When they are of one suit, it is calles straight flush.
(v. t.) To straighten.
Example Sentences:
(1) In contrast to L2 and L3 in L1 the mid gut runs down in a straight line without any looping.
(2) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(3) The region of the tentorium and straight sinus can occasionally give rise to a vermiform appearance (the "AVM artifact").
(4) In testing the contribution of the long, curved stem to the torsional stability of uncemented prostheses by comparing it with other stems, the long, curved stem was the most stable, followed by a shorter straight stem, and a short, proximally curved stem.
(5) Every time I have seen him since – you stand up straight and it’s: ‘Hi, boss.
(6) Both sets of experiments revealed a straight linear relationship between the dose of VC and the % foci area induced.
(7) Despite a few initial concerns about the technology and how it would fit into their daily routines, staff really see the benefit and find it rewarding to see the messages and be able to respond straight away.
(8) The results may be due to stronger social reinstatement tendencies in females than in males: Higher levels of social motivation facilitate behavioral performance when the task is easy (straight runway) and inhibit it when the task is difficult (V-shaped runway).
(9) The contrast threshold for line orientation was studied using two lines with the same orientation under three different experimental conditions (series): (1) the two lines were presented in the same part of the receptive field; (2) they were along the same straight line and separated by 14' visual angle; (3) they were parallel and displaced at 4' of visual angle.
(10) Only eye position proved statistically significant; straight-ahead eye position induced more bias than did fixation of the visual stimulus.
(11) Ultrastructural examination of a tumor with a typical cribriform pattern showed spaces of two types; the more frequent type was bounded by cells with straight plasma membranes and contained filamentous and basement-membrane-like material, and the less frequent type was surrounded by cells with numerous microvilli and contained nonfilamentous homogeneous material.
(12) The first problem facing Calderdale is sheep-rustling Happy Valley – filmed around Hebden Bridge, with its beautiful stone houses straight off the pages of the Guardian’s Lets Move To – may be filled with rolling hills and verdant pastures, but the reality of rural issues are harsh.
(13) Atlético Madrid maintained their faint hopes of catching Barcelona by recording a fourth straight league win, comfortably beating Deportivo la Coruña 3-0 with goals by the midfielder Saúl Ñíguez, top scorer Antoine Griezmann and Argentinian forward Ángel Correa.
(14) The chemotactic receptor-transducer proteins of Escherichia coli are responsible for directing the swimming behavior of cells by signaling for either straight swimming or tumbling in response to chemostimuli.
(15) These observations suggest that the inner dynein arms in Chlamydomonas axonemes are aligned not in a single straight row, but in a staggered row or two discrete rows.
(16) Following a run which included eight straight draws in the Premier League and a 3-0 defeat at Tottenham last Wednesday, Mubarak had reached the conclusion that Hughes and his coaching staff were not realising the potential of the players City had assembled.
(17) When plotted against [Ca]o on a double log scale, the above relation yielded a straight line with a slope of 1.0.
(18) The torque versus rotation curves can be divided into two straight regions and two transition zones.
(19) Its middle, straight portion (between 2.30 and 3.30 microns sarcomere spacings) extrapolated to zero tension at 3.49 microns sarcomere length.
(20) New observations include: (1) In 15 nm cross sections that show single 14.5 nm levels: (a) The flared X structure characteristic of rigor is replaced by a straight-X figure in which the crossbridge density is aligned along the myosin-actin plane, rather than skewed across it as in rigor.