(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Truncheon
Definition:
(n.) A short staff, a club; a cudgel; a shaft of a spear.
(n.) A baton, or military staff of command.
(n.) A stout stem, as of a tree, with the branches lopped off, to produce rapid growth.
(v. t.) To beat with a truncheon.
Example Sentences:
(1) In the police's own footage of what followed, shown in court, mounted officers with batons drawn can be seen charging into miners, and officers on foot beat miners about the head with truncheons.
(2) Camouflaged riot police bearing rubber truncheons hold back protesters begging the tsar for bread.
(3) People forget that you were very young and yet public enemy No 1, at the centre of incidents such as going on Bill Grundy's show and the police arriving with truncheons.
(4) I don't want to get hit in the face with a truncheon.
(5) Some 20 officers were seen brutally beating one protester with truncheons.
(6) The BBC showed miners throwing stones and other missiles at the police, followed by mounted officers charging into them, and then officers chasing miners, some clearly being hit over the head with truncheons.
(7) Arthur Critchlow, who suffered a fractured skull from a police truncheon and was arrested, held on remand and prosecuted for rioting – for which he was acquitted with 94 others – told the home secretary that his community has never trusted the police since.
(8) Excerpts On police uniforms "Having gone truncheons to tasers in a generation, I have to wonder what purpose the current police service has been built for ... we are mostly approachable and pleasant people, it's just that we dress like Imperial Stormtroopers.
(9) Miners, fighting to protect jobs in pits that were subsequently closed down after the strike was defeated, were truncheoned over the head, then several spent time in prison on remand, fearing very long sentences, while awaiting trial.
(10) The worst scenes of violence in the miners' dispute broke out at the Orgreave coking plant near Rotherham, Yorkshire, yesterday with cars being burned, stones, bricks and bottles being hurled, and policemen lashing out with truncheons.
(11) Truncheon-wielding police attacked the crowds after a small number of people – provocateurs, according to the opposition – broke windows and doors in a government building.
(12) On the other side of the ticket barrier a younger man is whacked with truncheons by two policemen.
(13) Soon afterwards the police gave up, handing their helmets, truncheons and shields to the crowd.
(14) There’s a reputational risk as well as financial risk Jerry Petherick, G4S Prison officers in Oakwood are not armed with truncheons, as they often are in state-run jails, but wear body cameras attached to a strip on their right shoulder – an innovation that has proved very successful, both at de-escalation of violent incidents (“As soon as they see the camera recording they swear a few times, and they calm down,” a guard says) and when recording the effects of overdosing on black mamba.
(15) In the latest of several protests by opposition activists who say their leader will be denied a fair chance at next year’s election, police fired teargas and beat demonstrators with truncheons on Monday to stop them storming the offices of the electoral commission in Nairobi.
(16) Over Friday night police in Kiev broke up the remnants of the anti-government demonstration , swinging truncheons and injuring many, news agencies and witnesses said.
(17) Masked men with truncheons and shields were seen at the entrance to the building as a crowd of about 400 people surrounded it, while police stood nearby but did not intervene.
(18) A police procedural that is much more than the sum of its parts – The Thick of It with truncheons, basically.
(19) "We do not want to be kept quiet by a policeman's truncheon," heavyweight boxer and opposition leader Vitali Klitschko told the crowd.
(20) He said: "And the Syrians seem to be taking a different approach as well, one that makes widespread use of firearms, while the Iranians have generally armed their internal security forces with less lethal means, such as teargas, truncheons, chains, and the like, to reduce the lethality of their response, and to scare off the more faint-hearted among the opposition.