(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Tunnel
Definition:
(n. .) A vessel with a broad mouth at one end, a pipe or tube at the other, for conveying liquor, fluids, etc., into casks, bottles, or other vessels; a funnel.
(n. .) The opening of a chimney for the passage of smoke; a flue; a funnel.
(n. .) An artificial passage or archway for conducting canals or railroads under elevated ground, for the formation of roads under rivers or canals, and the construction of sewers, drains, and the like.
(n. .) A level passage driven across the measures, or at right angles to veins which it is desired to reach; -- distinguished from the drift, or gangway, which is led along the vein when reached by the tunnel.
(v. t.) To form into a tunnel, or funnel, or to form like a tunnel; as, to tunnel fibrous plants into nests.
(v. t.) To catch in a tunnel net.
(v. t.) To make an opening, or a passageway, through or under; as, to tunnel a mountain; to tunnel a river.
Example Sentences:
(1) When the Tunnel closed, Hardee decamped in 1991 to Up The Creek - a slightly better behaved venue in nearby Greenwich, which Hardee described as "the Tunnel with A-levels".
(2) Tunnel-like formations at different depths of the oral epithelium contained higher numbers of bacteria than those seen on the adjacent oral surface.
(3) The various theories of carpal tunnel syndrome (CTS) are reviewed.
(4) Tension in flexor tendons during wrist flexion may play a role in otherwise unexplained instances of the carpal tunnel syndrome.
(5) The results of the Tinel percussion test, the Phalen wrist-flexion test, and the new test were evaluated in thirty-one patients (forty-six hands) in whom the presence of carpal tunnel syndrome had been proved electrodiagnostically, as well as in a control group of fifty subjects.
(6) Eighteen patients with various mucopolysaccharidoses or mucolipidosis III were studied electrophysiologically to determine the presence or absence of carpal tunnel syndrome.
(7) Tenosynovial biopsy specimens from 177 wrists were obtained from patients at carpal tunnel release, and a control group of 19 specimens was also obtained.
(8) Headache and vertigo were not linked with exposure to vibration in forestry and a significant part of the numbness reported may be due to the carpal tunnel syndrome.
(9) Carpal tunnel syndrome is the most common and best known of the compression neuropathies in the upper extremity.
(10) Guzmán was sent to Altiplano high-security prison, 56 miles outside Mexico City, but in July 2015, he absconded again, squeezing through a hole in his shower floor then fleeing on a modified motorbike through a mile-long tunnel fitted with lights and a ventilation system.
(11) The paper examines a microsurgical technique of neurolysis and epineurotomy in the treatment of the carpal tunnel syndrome.
(12) MRI allowed the direct demonstration of carpal tunnel abnormalities in 8 cases, while abnormal findings in the median nerve were observed in 18 patients.
(13) Eight hundred twenty-one median nerves were retrospectively and prospectively reviewed for variations during operations to treat carpal tunnel syndrome.
(14) A vibration-rotation-tunneling band of the perdeuterated cluster has been measured near 89.6 wave numbers by tunable far infrared laser absorption spectroscopy.
(15) These two electrophysiological abnormalities are indicative of a focal segmental demyelination as the primary pathological process in tarsal tunnel syndrome.
(16) The adaptive value of sound signal characteristics for transmission in the underground tunnel ecotope was tested using tunnels of the solitary territorial subterranean mole rats.
(17) Plasma cortisol concentrations were highest in fish exposed to both the combined stress of WSF exposure and of forced swimming in a stamina tunnel.
(18) "A typical day in London would be: wake up hungover, try to get some breakfast in you," he says, barrelling along green-tunnelled country lanes through – as he puts it in Jerusalem – the "wild garlic and May blossom" that mean winter is over.
(19) A high origin of the right coronary artery or location of the left coronary artery adjacent to a pulmonary cusp or branch may complicate the tunnel-type repair.
(20) The wrists of 16 normal volunteers were examined via high-resolution sonography with special reference to the carpal tunnel.