(v. t.) To cause to open in slits or chinks; to split; to cause the skin of to crack or become rough.
(v. t.) To strike; to beat.
(v. i.) To crack or open in slits; as, the earth chaps; the hands chap.
(v. i.) To strike; to knock; to rap.
(n.) A cleft, crack, or chink, as in the surface of the earth, or in the skin.
(n.) A division; a breach, as in a party.
(n.) A blow; a rap.
(n.) One of the jaws or the fleshy covering of a jaw; -- commonly in the plural, and used of animals, and colloquially of human beings.
(n.) One of the jaws or cheeks of a vise, etc.
(n.) A buyer; a chapman.
(n.) A man or boy; a youth; a fellow.
(v. i.) To bargain; to buy.
Example Sentences:
(1) For this, different detergents such as Triton X-100, CHAPS and n-octyl beta-D glucopyranoside were tested at various concentrations, durations and temperatures of incubation.
(2) At detergent concentrations above their critical micelle concentrations, C12E8 was also much more effective than CHAPS, suggesting that micelles are not involved.
(3) That’s plain wrong, has been for decades, and a clever chap like Nelson should know it.
(4) End-on views of G on virus clearly showed triangles consisting of three dots indicating the trimeric nature of native G. End-on views of CHAPS-isolated G showed very similar triangles confirming that, using this detergent, G was solubilized in its native trimeric structure.
(5) Previous investigations (El Mestikawy et al., J Neurochem 51: 1031-1040, 1988) have shown that 5-HT1A binding sites (R[5-HT1A]) solubilized by CHAPS from rat hippocampal membranes can be modulated by guanine nucleotides, as expected from their solubilization together with associated G regulatory proteins (G).
(6) Initially, peripheral polypeptides were removed from apically enriched vesicles by washing with alkaline buffer (pH 10.8) containing 2 mM CHAPS.
(7) The enzymes could be solubilized from the membrane fractions using CHAPS, and the detergent-soluble activity partially restored by addition of phospholipids.
(8) Furthermore, the effects of detergents other than CHAPS on hydrodynamic parameters and on [3H]TCDD binding to the receptor were studied.
(9) Cation exchange chromatography on carboxymethylcellulose-Sephadex with a starting buffer of pH 5 containing 2 mM CHAPS plus 20 mM beta-OG, followed by a pH 8 buffer, showed a very small OD peak at the void volume (P) and a second peak with about 95% of the protein (E).
(10) The binding of CHAPS to the SynChropak Propyl stationary phase and its effects on retention were found to be readily reversible.
(11) Leukotriene C4 (LTC4) synthase was solubilized from the microsomes of guinea-pig lung by the new procedures of a combination of 3-[3-cholamidopropyl)dimethylammonio)-1-propanesulfonate (CHAPS), digitonin and KCl.
(12) These treatments also caused an altered distribution of phosphorylated integrin between the CHAPS soluble and insoluble fractions.
(13) The ryanodine receptor protein of sheep cardiac muscle sarcoplasmic reticulum membranes functions as a ligand-regulated ion channel following solubilization with the zwitterionic detergent CHAPS (3-[(3-cholamidopropyl)-dimethylammonio]-1- propane sulphonate); purification by density gradient centrifugation, reconstitution into proteo-liposomes and incorporation into planar phospholipid bilayers.
(14) The chap who assessed my brother was a physiotherapist,” she said.
(15) The augmentation of tone was endothelium-dependent as it did not occur following functional destruction of the endothelium by perfusion of the vascular bed with the detergent CHAPS (0.3%) for 150s.
(16) Isoelectric focusing in 2% 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) without urea gives good results as does 2% Nonidet-P40 with 8 M urea.
(17) Sodium nitroprusside was approximately 200 times less potent than acetylcholine in the presence of the endothelium and was the only vasorelaxant to be active after destruction of the endothelium by perfusion with 0.3% CHAPS; in the absence of the endothelium it was 3.7 times more potent as a vasodilator than in its presence.
(18) Among three detergents tested, CHAPS is the best in preserving hormonal binding affinity and specificity.
(19) In addition, the 44% peak became increasingly resistant to the inhibitory effect of CHAPS.
(20) Optimal yield was obtained by pretreatment of whole M. pneumoniae cells with buffer containing 1% Chaps and subsequent extraction with octylglucosid at a detergent to protein ratio of 5 and at octylglycoside concentrations between 1.5 and 2%.
Cleft
Definition:
(imp.) of Cleave
(p. p.) of Cleave
() imp. & p. p. from Cleave.
(a.) Divided; split; partly divided or split.
(a.) Incised nearly to the midrib; as, a cleft leaf.
(n.) A space or opening made by splitting; a crack; a crevice; as, the cleft of a rock.
(n.) A piece made by splitting; as, a cleft of wood.
(n.) A disease in horses; a crack on the band of the pastern.
Example Sentences:
(1) Intraepidermal clefting starts at the junction between the basal and epidermal layers, and later involves all of the levels of the stratum spinosum.
(2) Closure of both cleft spaces by orthodontic means was achieved in 20 of the 21 patients in the first group, and in 14 of the 20 patients in the second group.
(3) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
(4) Both types of oral cleft, cleft palate (CP) and cleft lip with or without CP (CLP), segregate in these families together with lower lip pits or fistulae in an autosomal dominant mode with high penetrance estimated to be K = .89 and .99 by different methods.
(5) Three different structures have been observed among the binding proteins: unliganded 'open cleft', liganded 'open cleft', and liganded 'closed cleft'.
(6) Retrognathia or retrusion of the maxilla and mid-face is present in about one-third of treated cleft palate patients.
(7) At S-L clefts, paranodal-nodal regions, and Schwann cell nuclei, the axonal areas were smaller and the NF densities were higher than at compact myelinated regions.
(8) Cleft palate was found in 98.1% of fetuses in the positive control group and none of them in the negative control group.
(9) Recent reports have indicated the usefulness of nuclear grooves (clefts or notches) as an additional criterion for the diagnosis of papillary thyroid carcinoma in fine needle aspirates; most of these studies were carried out on alcohol-fixed material stained with the Papanicolaou stain or with hematoxylin and eosin, which yield good nuclear details.
(10) The question of how the contraction of adjacent endothelial cells might widen the intercellular clefts and thus regulate permeability is discussed.
(11) An examination of 9720 Zagreb school children, 6-13 years of age, revealed submucous cleft palate (SMCP) in 5 and cleft uvula in 232.
(12) These factors include narrowing of septal arteries and the artery to the atrioventricular node, preservation of fetal anatomy with dispersion in the atrioventricular node and His bundle, fibrosis of the sinus node, clefts in the septum, multiple atrioventricular pathways and massive myocardial infarction.
(13) Although maternal ingestion of antiepileptic drugs is strongly suspected of causing congenital defects, particularly oral clefts, the effect of epilepsy itself or a combined effect of drug intake and epilepsy have not been excluded as etiological factors.
(14) To clarify the mechanism by which retinoid causes cleft palate, we investigated the effect of retinoic acid (RA) on proliferation activity and glycosaminoglycan (GAG) synthesis in mouse fetuses palatal mesenchymal (MFPM) cells.
(15) The blood lymphocytes were small with scanty cytoplasm, densely condensed nuclear chromatin, and deep clefts originating in sharp angles from the nuclear surface.
(16) The familial association of epilepsy and cleft lip with or without cleft palate (CL (P)) is analyzed assuming both entities share common genetic predisposing factors.
(17) In the following, there will be indicated the approved techniques and methods of suturing the cleft palate and a new method will be discussed related to the reciprocal Z-type plastic operation.
(18) Fifty per cent of the children with clefts of the palate and lip had deviated nasal septum producing nasal obstruction.
(19) A family is reported of 500 facial cleft index cases, attendees for plastic surgery review at hospitals in northern England.
(20) An infant with a complete unilateral cleft of the lip and palate underwent maxillary expansion treatment using an oral orthopedic appliance.