(v. t.) To cause to open in slits or chinks; to split; to cause the skin of to crack or become rough.
(v. t.) To strike; to beat.
(v. i.) To crack or open in slits; as, the earth chaps; the hands chap.
(v. i.) To strike; to knock; to rap.
(n.) A cleft, crack, or chink, as in the surface of the earth, or in the skin.
(n.) A division; a breach, as in a party.
(n.) A blow; a rap.
(n.) One of the jaws or the fleshy covering of a jaw; -- commonly in the plural, and used of animals, and colloquially of human beings.
(n.) One of the jaws or cheeks of a vise, etc.
(n.) A buyer; a chapman.
(n.) A man or boy; a youth; a fellow.
(v. i.) To bargain; to buy.
Example Sentences:
(1) For this, different detergents such as Triton X-100, CHAPS and n-octyl beta-D glucopyranoside were tested at various concentrations, durations and temperatures of incubation.
(2) At detergent concentrations above their critical micelle concentrations, C12E8 was also much more effective than CHAPS, suggesting that micelles are not involved.
(3) That’s plain wrong, has been for decades, and a clever chap like Nelson should know it.
(4) End-on views of G on virus clearly showed triangles consisting of three dots indicating the trimeric nature of native G. End-on views of CHAPS-isolated G showed very similar triangles confirming that, using this detergent, G was solubilized in its native trimeric structure.
(5) Previous investigations (El Mestikawy et al., J Neurochem 51: 1031-1040, 1988) have shown that 5-HT1A binding sites (R[5-HT1A]) solubilized by CHAPS from rat hippocampal membranes can be modulated by guanine nucleotides, as expected from their solubilization together with associated G regulatory proteins (G).
(6) Initially, peripheral polypeptides were removed from apically enriched vesicles by washing with alkaline buffer (pH 10.8) containing 2 mM CHAPS.
(7) The enzymes could be solubilized from the membrane fractions using CHAPS, and the detergent-soluble activity partially restored by addition of phospholipids.
(8) Furthermore, the effects of detergents other than CHAPS on hydrodynamic parameters and on [3H]TCDD binding to the receptor were studied.
(9) Cation exchange chromatography on carboxymethylcellulose-Sephadex with a starting buffer of pH 5 containing 2 mM CHAPS plus 20 mM beta-OG, followed by a pH 8 buffer, showed a very small OD peak at the void volume (P) and a second peak with about 95% of the protein (E).
(10) The binding of CHAPS to the SynChropak Propyl stationary phase and its effects on retention were found to be readily reversible.
(11) Leukotriene C4 (LTC4) synthase was solubilized from the microsomes of guinea-pig lung by the new procedures of a combination of 3-[3-cholamidopropyl)dimethylammonio)-1-propanesulfonate (CHAPS), digitonin and KCl.
(12) These treatments also caused an altered distribution of phosphorylated integrin between the CHAPS soluble and insoluble fractions.
(13) The ryanodine receptor protein of sheep cardiac muscle sarcoplasmic reticulum membranes functions as a ligand-regulated ion channel following solubilization with the zwitterionic detergent CHAPS (3-[(3-cholamidopropyl)-dimethylammonio]-1- propane sulphonate); purification by density gradient centrifugation, reconstitution into proteo-liposomes and incorporation into planar phospholipid bilayers.
(14) The chap who assessed my brother was a physiotherapist,” she said.
(15) The augmentation of tone was endothelium-dependent as it did not occur following functional destruction of the endothelium by perfusion of the vascular bed with the detergent CHAPS (0.3%) for 150s.
(16) Isoelectric focusing in 2% 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) without urea gives good results as does 2% Nonidet-P40 with 8 M urea.
(17) Sodium nitroprusside was approximately 200 times less potent than acetylcholine in the presence of the endothelium and was the only vasorelaxant to be active after destruction of the endothelium by perfusion with 0.3% CHAPS; in the absence of the endothelium it was 3.7 times more potent as a vasodilator than in its presence.
(18) Among three detergents tested, CHAPS is the best in preserving hormonal binding affinity and specificity.
(19) In addition, the 44% peak became increasingly resistant to the inhibitory effect of CHAPS.
(20) Optimal yield was obtained by pretreatment of whole M. pneumoniae cells with buffer containing 1% Chaps and subsequent extraction with octylglucosid at a detergent to protein ratio of 5 and at octylglycoside concentrations between 1.5 and 2%.
Dog
Definition:
(n.) A quadruped of the genus Canis, esp. the domestic dog (C. familiaris).
(n.) A mean, worthless fellow; a wretch.
(n.) A fellow; -- used humorously or contemptuously; as, a sly dog; a lazy dog.
(n.) One of the two constellations, Canis Major and Canis Minor, or the Greater Dog and the Lesser Dog. Canis Major contains the Dog Star (Sirius).
(n.) An iron for holding wood in a fireplace; a firedog; an andiron.
(n.) A grappling iron, with a claw or claws, for fastening into wood or other heavy articles, for the purpose of raising or moving them.
(n.) An iron with fangs fastening a log in a saw pit, or on the carriage of a sawmill.
(n.) A piece in machinery acting as a catch or clutch; especially, the carrier of a lathe, also, an adjustable stop to change motion, as in a machine tool.
(v. t.) To hunt or track like a hound; to follow insidiously or indefatigably; to chase with a dog or dogs; to worry, as if by dogs; to hound with importunity.
Example Sentences:
(1) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(2) The combined immediate and delayed responses to fleas in the dog are as observed by other investigators in man and guinea pigs.
(3) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
(4) It was shown in experiments on four dogs by the conditioned method that the period of recovery of conditioned activity after one hour ether anaesthesia tested 7 to 7.5 days.
(5) Dialysis of dog plasma against an artificial c.s.f.
(6) For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.
(7) Complete heart block was produced in 20 of 20 dogs.
(8) The dog and the pig also have an endoperoxide-sensitive constrictor system activated by the 11,9-(epoxymethano) analogue of PGH2 and, of particular note, ICI 79939 and its 11-oxo analogue.
(9) All of this in the same tones of weary nonchalance you might use to stop the dog nosing around in the bin.
(10) One hundred and twelve dogs, including twenty C3-deficient dogs, were studied over a period of 6 years.
(11) From the present results it is concluded that secretion of extrapancreatic glucagon increased in response to arginine infusion in the diabetic state, both alloxan diabetic dogs and one-week post-pancreatectomized dogs.
(12) The effect of pO(2) was studied in a further nine dogs.
(13) The effects of tachycardia caused by ectopic right or left ventricular stimulation on ventricular recovery potentials were studied in 30 dogs.
(14) Stimulation with these electrodes were effective for inducing voiding with little residual volume after the recovery of bladder reflexes, 3 weeks after experimental spinal cord injury in the dog.
(15) A neodymium YAG (Nd:YAG) laser was evaluated in a dog ulcer model used in the same manner as is recommended for bleeding patients (power 55 W, divergence angle 4 degrees, with CO2 gas-jet assistance).
(16) Hollywood legend has it that, at the first Academy awards in 1929, Rin Tin Tin the dog won most votes for best actor.
(17) Liver bloodflow remained unchanged in AS dogs, but hepatic alanine uptake nearly tripled (p less than 0.01) and hepatic glucose production increased by 60% (p less than 0.05).
(18) Affected dogs were from ten breeds and their average age was eight years.
(19) Though three of these presumable metabolites could slightly inhibit the binding of [3H]-KW-3049, they were not detected in rat and dog plasma at 0.5 h after oral administration of KW-3049.
(20) Temelastine produces these species-specific changes by enhancing thyroxine clearance from the circulation in the rat, but not in the dog or mouse.