(v. t.) To cause to open in slits or chinks; to split; to cause the skin of to crack or become rough.
(v. t.) To strike; to beat.
(v. i.) To crack or open in slits; as, the earth chaps; the hands chap.
(v. i.) To strike; to knock; to rap.
(n.) A cleft, crack, or chink, as in the surface of the earth, or in the skin.
(n.) A division; a breach, as in a party.
(n.) A blow; a rap.
(n.) One of the jaws or the fleshy covering of a jaw; -- commonly in the plural, and used of animals, and colloquially of human beings.
(n.) One of the jaws or cheeks of a vise, etc.
(n.) A buyer; a chapman.
(n.) A man or boy; a youth; a fellow.
(v. i.) To bargain; to buy.
Example Sentences:
(1) For this, different detergents such as Triton X-100, CHAPS and n-octyl beta-D glucopyranoside were tested at various concentrations, durations and temperatures of incubation.
(2) At detergent concentrations above their critical micelle concentrations, C12E8 was also much more effective than CHAPS, suggesting that micelles are not involved.
(3) That’s plain wrong, has been for decades, and a clever chap like Nelson should know it.
(4) End-on views of G on virus clearly showed triangles consisting of three dots indicating the trimeric nature of native G. End-on views of CHAPS-isolated G showed very similar triangles confirming that, using this detergent, G was solubilized in its native trimeric structure.
(5) Previous investigations (El Mestikawy et al., J Neurochem 51: 1031-1040, 1988) have shown that 5-HT1A binding sites (R[5-HT1A]) solubilized by CHAPS from rat hippocampal membranes can be modulated by guanine nucleotides, as expected from their solubilization together with associated G regulatory proteins (G).
(6) Initially, peripheral polypeptides were removed from apically enriched vesicles by washing with alkaline buffer (pH 10.8) containing 2 mM CHAPS.
(7) The enzymes could be solubilized from the membrane fractions using CHAPS, and the detergent-soluble activity partially restored by addition of phospholipids.
(8) Furthermore, the effects of detergents other than CHAPS on hydrodynamic parameters and on [3H]TCDD binding to the receptor were studied.
(9) Cation exchange chromatography on carboxymethylcellulose-Sephadex with a starting buffer of pH 5 containing 2 mM CHAPS plus 20 mM beta-OG, followed by a pH 8 buffer, showed a very small OD peak at the void volume (P) and a second peak with about 95% of the protein (E).
(10) The binding of CHAPS to the SynChropak Propyl stationary phase and its effects on retention were found to be readily reversible.
(11) Leukotriene C4 (LTC4) synthase was solubilized from the microsomes of guinea-pig lung by the new procedures of a combination of 3-[3-cholamidopropyl)dimethylammonio)-1-propanesulfonate (CHAPS), digitonin and KCl.
(12) These treatments also caused an altered distribution of phosphorylated integrin between the CHAPS soluble and insoluble fractions.
(13) The ryanodine receptor protein of sheep cardiac muscle sarcoplasmic reticulum membranes functions as a ligand-regulated ion channel following solubilization with the zwitterionic detergent CHAPS (3-[(3-cholamidopropyl)-dimethylammonio]-1- propane sulphonate); purification by density gradient centrifugation, reconstitution into proteo-liposomes and incorporation into planar phospholipid bilayers.
(14) The chap who assessed my brother was a physiotherapist,” she said.
(15) The augmentation of tone was endothelium-dependent as it did not occur following functional destruction of the endothelium by perfusion of the vascular bed with the detergent CHAPS (0.3%) for 150s.
(16) Isoelectric focusing in 2% 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) without urea gives good results as does 2% Nonidet-P40 with 8 M urea.
(17) Sodium nitroprusside was approximately 200 times less potent than acetylcholine in the presence of the endothelium and was the only vasorelaxant to be active after destruction of the endothelium by perfusion with 0.3% CHAPS; in the absence of the endothelium it was 3.7 times more potent as a vasodilator than in its presence.
(18) Among three detergents tested, CHAPS is the best in preserving hormonal binding affinity and specificity.
(19) In addition, the 44% peak became increasingly resistant to the inhibitory effect of CHAPS.
(20) Optimal yield was obtained by pretreatment of whole M. pneumoniae cells with buffer containing 1% Chaps and subsequent extraction with octylglucosid at a detergent to protein ratio of 5 and at octylglycoside concentrations between 1.5 and 2%.
Knock
Definition:
(v. i.) To drive or be driven against something; to strike against something; to clash; as, one heavy body knocks against another.
(v. i.) To strike or beat with something hard or heavy; to rap; as, to knock with a club; to knock on the door.
(v. t.) To strike with something hard or heavy; to move by striking; to drive (a thing) against something; as, to knock a ball with a bat; to knock the head against a post; to knock a lamp off the table.
(v. t.) To strike for admittance; to rap upon, as a door.
(n.) A blow; a stroke with something hard or heavy; a jar.
(n.) A stroke, as on a door for admittance; a rap.
Example Sentences:
(1) Having been knocked out of the League Cup and Cup Winners' Cup before Christmas, they lost an FA Cup fourth-round replay at West Brom on 1 February.
(2) It pulled to a halt and a bodyguard got out and knocked me unconscious.
(3) More seriously, but no less predictably, the inflaming of sectarianism will have knock-on effects in Syria and Iraq.
(4) I knocked for quite some time but there was nobody there.” A neighbour said the family had not been home for “a while”.
(5) One day, out of the blue, there's a knock on the door.
(6) At 7.40am Lord Feldman, the Conservative party chairman, knocked on the front door of No 10.
(7) Indeed, with the pageantry already knocked off the top of the news by reports from Old Trafford, the very idea of a cohesive coalition programme about anything other than cuts looks that bit harder to sustain.
(8) Davenport, possibly in a fit of pique at having been knocked out, said playing Mauresmo was like 'playing a guy'.
(9) This part will be knocked down next year; they have already started opposite."
(10) I see myself in exactly the same situation as I saw myself yesterday, though obviously with the bitter disappointment of the failure of being knocked out.
(11) "There's nothing better than when the Grammys can rock out, and to have these artists all together on one stage, doing a number that, when they presented it to us, knocked us out, is going to turn out to be one of those Grammy moments that people talk about for a long time.
(12) Hester also pledged that customers from other banks will be repaid for 'knock-on' costs after they were left out of pocket by an IT failure that sent 20m transactions awry.
(13) Whether it's voting on the day, knocking on doors, making phone calls or speaking to friends and family, the silent majority should feel confident in speaking up.
(14) Cooled by a floor fan, nurses, doctors and support staff in blue scrubs move through the small anteroom next to the isolation ward to juggle the needs of the desperately ill patients inside as a stream of people knock on the canvas door asking for updates on their loved ones.
(15) We’ve sent out all the boards and there’s still loads of people flooding in, we don’t know what to do.’ It happened in Leeds North West, too – they started the day, they had so many activists that they went: ‘Right, let’s scrap our whole strategy, we’re going to just print off the electoral register instead’ – and rather than focusing on likely Labour voters, which is what you would normally do, they knocked on all the doors on the electoral register – that’s unheard of.” The seat saw a 14% swing to Labour, overturning a Lib Dem majority of almost 3,000 and replacing it with a 4,000 Labour lead.
(16) Offers worth £20m and £26m have been flatly rejected by Everton since mid-July, with a third of around £30m also knocked back last week.
(17) A protester is knocked back by a police water cannon as riot police advance towards Gezi Park.
(18) Chelsea , however, will not be too concerned if this match is added to the long list of games that is used to knock José Mourinho's ploys of conservatism and, ultimately, it is proven to be a valuable result.
(19) You are hunting for signs of the assembly of injuries - a broken nose, knocked-out teeth, fractured eye socket - incurred by falling face-first down a fire escape in Michigan while high on crystal meth, crack cocaine and cheap wine.
(20) On election day, we’ll have 6,000 campaign volunteers knocking on doors.