What's the difference between chap and lad?

Chap


Definition:

  • (v. t.) To cause to open in slits or chinks; to split; to cause the skin of to crack or become rough.
  • (v. t.) To strike; to beat.
  • (v. i.) To crack or open in slits; as, the earth chaps; the hands chap.
  • (v. i.) To strike; to knock; to rap.
  • (n.) A cleft, crack, or chink, as in the surface of the earth, or in the skin.
  • (n.) A division; a breach, as in a party.
  • (n.) A blow; a rap.
  • (n.) One of the jaws or the fleshy covering of a jaw; -- commonly in the plural, and used of animals, and colloquially of human beings.
  • (n.) One of the jaws or cheeks of a vise, etc.
  • (n.) A buyer; a chapman.
  • (n.) A man or boy; a youth; a fellow.
  • (v. i.) To bargain; to buy.

Example Sentences:

  • (1) For this, different detergents such as Triton X-100, CHAPS and n-octyl beta-D glucopyranoside were tested at various concentrations, durations and temperatures of incubation.
  • (2) At detergent concentrations above their critical micelle concentrations, C12E8 was also much more effective than CHAPS, suggesting that micelles are not involved.
  • (3) That’s plain wrong, has been for decades, and a clever chap like Nelson should know it.
  • (4) End-on views of G on virus clearly showed triangles consisting of three dots indicating the trimeric nature of native G. End-on views of CHAPS-isolated G showed very similar triangles confirming that, using this detergent, G was solubilized in its native trimeric structure.
  • (5) Previous investigations (El Mestikawy et al., J Neurochem 51: 1031-1040, 1988) have shown that 5-HT1A binding sites (R[5-HT1A]) solubilized by CHAPS from rat hippocampal membranes can be modulated by guanine nucleotides, as expected from their solubilization together with associated G regulatory proteins (G).
  • (6) Initially, peripheral polypeptides were removed from apically enriched vesicles by washing with alkaline buffer (pH 10.8) containing 2 mM CHAPS.
  • (7) The enzymes could be solubilized from the membrane fractions using CHAPS, and the detergent-soluble activity partially restored by addition of phospholipids.
  • (8) Furthermore, the effects of detergents other than CHAPS on hydrodynamic parameters and on [3H]TCDD binding to the receptor were studied.
  • (9) Cation exchange chromatography on carboxymethylcellulose-Sephadex with a starting buffer of pH 5 containing 2 mM CHAPS plus 20 mM beta-OG, followed by a pH 8 buffer, showed a very small OD peak at the void volume (P) and a second peak with about 95% of the protein (E).
  • (10) The binding of CHAPS to the SynChropak Propyl stationary phase and its effects on retention were found to be readily reversible.
  • (11) Leukotriene C4 (LTC4) synthase was solubilized from the microsomes of guinea-pig lung by the new procedures of a combination of 3-[3-cholamidopropyl)dimethylammonio)-1-propanesulfonate (CHAPS), digitonin and KCl.
  • (12) These treatments also caused an altered distribution of phosphorylated integrin between the CHAPS soluble and insoluble fractions.
  • (13) The ryanodine receptor protein of sheep cardiac muscle sarcoplasmic reticulum membranes functions as a ligand-regulated ion channel following solubilization with the zwitterionic detergent CHAPS (3-[(3-cholamidopropyl)-dimethylammonio]-1- propane sulphonate); purification by density gradient centrifugation, reconstitution into proteo-liposomes and incorporation into planar phospholipid bilayers.
  • (14) The chap who assessed my brother was a physiotherapist,” she said.
  • (15) The augmentation of tone was endothelium-dependent as it did not occur following functional destruction of the endothelium by perfusion of the vascular bed with the detergent CHAPS (0.3%) for 150s.
  • (16) Isoelectric focusing in 2% 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) without urea gives good results as does 2% Nonidet-P40 with 8 M urea.
  • (17) Sodium nitroprusside was approximately 200 times less potent than acetylcholine in the presence of the endothelium and was the only vasorelaxant to be active after destruction of the endothelium by perfusion with 0.3% CHAPS; in the absence of the endothelium it was 3.7 times more potent as a vasodilator than in its presence.
  • (18) Among three detergents tested, CHAPS is the best in preserving hormonal binding affinity and specificity.
  • (19) In addition, the 44% peak became increasingly resistant to the inhibitory effect of CHAPS.
  • (20) Optimal yield was obtained by pretreatment of whole M. pneumoniae cells with buffer containing 1% Chaps and subsequent extraction with octylglucosid at a detergent to protein ratio of 5 and at octylglycoside concentrations between 1.5 and 2%.

Lad


Definition:

  • () p. p. of Lead, to guide.
  • (n.) A boy; a youth; a stripling.
  • (n.) A companion; a comrade; a mate.

Example Sentences:

  • (1) To be fair to lads who find themselves just a bus ride from Auschwitz, a visit to the camp is now considered by many tourists to be a Holocaust "bucket list item", up there with the Anne Frank museum, where Justin Bieber recently delivered this compliment : "Anne was a great girl.
  • (2) They caught all three of them and then proceeded to let the two white lads go."
  • (3) This brings lads like 12-year-old Matthew Mason down from the magnificent studio his father Mark, from a coal-mining town ravaged by pit closures, lovingly built him in the back garden at Gants Hill, north-east London.
  • (4) As part of two Department of Veterans Affairs Cooperative Trials, we obtained angiographic patency data for internal mammary artery (IMA) and saphenous vein grafts to the left anterior descending (LAD) coronary artery at 1 year after coronary artery bypass surgery.
  • (5) Most patients had obstruction or severe stenosis of the proximal LAD coronary artery together with a poor runoff as demonstrated angiographically.
  • (6) LAD to LCCA collaterals serve as functionally significant bidirectional perfusion conduits, and monitoring of collateral perfusion development is practical by measuring the step reduction in LCCA flow upon abrupt release of an LAD occlusion.
  • (7) In a forth patient with occulsion of the LAD, there was no response to intracoronary NTG and mechanical recanalization was not attempted.
  • (8) In addition, Northern analysis of mRNA expression also demonstrated that the transfected LAD patient cells were expressing high quantities of exogenous beta subunit mRNA.
  • (9) And he enjoyed holding court to pretty girls and jolly lads at the Academy Club, a bohemian joint he founded next to his office.
  • (10) When the LAD perfusion was switched from aortic perfusion to the systolic one, the subendocardial PO2 decreased to 9.8 mmHg, on an average, in 1 to 2 min from the initial level of 18.9 mmHg obtained during the aortic perfusion.
  • (11) Group I (n = 7) had normal LAD, group II (n = 18) had LAD stenosis of varying degrees.
  • (12) 4) The unfolded map diagnosis with apical display obtained from long-axis tomogram was useful to diagnose left anterior descending coronary (LAD) lesion, which improve not only the sensitivity of LAD but also specificity of right coronary artery single vessel disease.
  • (13) The anterior descending coronary artery (LAD) was partially occluded causing an average 71% reduction in its blood flow.
  • (14) They had a good threat up top with the two lads up front, who messed us around all day long to be honest.
  • (15) Six of 16 had stenosis of a single coronary artery [left anterior descending coronary artery (LAD), four; right coronary artery (RCA), two]; four of six survived RVD.
  • (16) Ischaemia was produced by decreasing the perfusion blood flow of the LAD to 50% (moderate ischaemia) and 27% (severe ischemia) of normal.
  • (17) There are absolutely no egos and the Premier League boys are so welcoming and have made it easy to fit in both with the style of play and behind the scenes with the lads.
  • (18) To assess the validity of the quantitative 201Tl scintimetry in various diseases of the heart (coronary heart disease with and without myocardial infarction, non-coronary cardiomyopathy, scleroderma heart disease and asymmetric septal hypertrophy with IHSS), the 201Tl myocardial uptake values for five standardized projections (a) were correlated with the grade of LAD stenosis, (b) the pattern of myocardial wall motion and (c) were compared with the 201Tl uptake values derived from normal patients.
  • (19) The LAD regions of the same hearts served as untreated control myocardium.
  • (20) Everything happens for Alan Shearer - he's a lucky lad like that.

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