(1) "Countless generations of girls were sentenced to lives lacking in sexual pleasure or fulfilment and cheerless marriages."
(2) But is the dilemma posed here in this ugly, cheerless Bohemia supposed to be typical?
(3) But for most homeowners, especially those who have come to view their home as a form of pension, the outlook is cheerless.
(4) And of course the authorities are incensed, affirming once again that old adage: there is only one thing more cheerless than a Magi with a severed head – a local bureaucrat armed with zoning laws.
(5) "It was pitiable to see these poor people struggling with their adversity, and to think of the cheerless night they must spend amid their sodden surroundings," the Eastern Daily Press wrote.
(6) Dedicated websites flog dried food, gas masks and other cheerless items.
(7) They are being turned by the companies that run them into soulless, cheerless, pasteurised piazzas, in which plastic policemen harry anyone loitering without intent to shop.
(8) If it is possible to whimper at the volume of a bang, then that is how this decade is ending on the big screen: with two high-profile, high-budget movies about the end of the world: Roland Emmerich's cheerfully silly 2012, and John Hillcoat's cheerlessly serious The Road , which arrive with a good deal of commentary to the effect that these movies typify the zeitgeist of the decade.
(9) Like a rich country fruit cake, Kidnapped is seasoned throughout with handfuls of dialect words, "ain" (one), "bairn" (child), "blae" (cheerless), "chield" (fellow), "drammach" (raw oatmeal), "fash" (bother), "muckle" (big), "siller" (money), "unco" (extremely) , "wheesht!"
(10) The Telegraph, meanwhile, said the film was "a special class of awful" while The Mirror labelled it "cheap and cheerless".
(11) The changes of basic mood, however, which are characteristic of depression, such as cheerlessness and apathy, are the dopamine of antidepressive medication; only these drugs can re-establish the biochemical balance to a large extent.
(12) As the cheerless skies and grim economy sap all will to return to work, take heart that even on a trip to Mars , it is hard to get out of bed in the morning.
(13) And will amateur property developers, who, thanks to Sarah Beeny and Kirstie Allsopp's television programmes, have been nurturing nauseating dreams of squeezing vast profits from cheap and cheerless accommodation, come hideously unstuck?
(14) Anyone who doesn't think that if they could just have her in their bedroom at seven o'clock on a Friday night, in control of the white wine, the Elnett and the minicab booking, that life would somehow never be cheerless again?
(15) Let me close with Sir William Osler's metaphor: How common the experience to enter a cold cheerless room in which the fire in the grate has died down, not from lack of coal, not because the coal was not alight, but the bits, large and small, falling away from each other have gradually become dark and cold.
Depressing
Definition:
(p. pr. & vb. n.) of Depress
Example Sentences:
(1) He's Billy no-mates with a Heckler & Koch sniper-rifle, drowning in loneliness, booze and depression.
(2) Thyroid replacement led to resolution of both apnea and depression.
(3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(4) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(5) Further, at the end of treatment fewer patients had depressive symptoms and the total daily number of hours of wellbeing and normal movement increased.
(6) The active agents modestly improved treadmill exercise duration time until 1 mm ST segment depression (3%), and only propranolol and diltiazem had significant effects.
(7) The ED50 and ED95 of mivacurium in each group were estimated from linear regression plots of log dose vs probit of maximum percentage depression of neuromuscular function.
(8) The data are compared with the results from 79 patients with a bipolar depression, 192 with a neurotic depression and 89 with a depressive reaction.
(9) A similar depressed receptor function was observed for C3b, fibronectin, and some lectins.
(10) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(11) Both treatments depressed nocturnal pineal melatonin content in rats and hamsters.
(12) Infusion of sodium lactate associated with isoproterenol could be used to combat the depressent effects of betablockers in patients with cardiac disorders.
(13) We studied the effects of the localisation and size of ischemic brain infarcts and the influence of potential covariates (gender, age, time since infarction, physical handicap, cognitive impairment, aphasia, cortical atrophy and ventricular size) on 'post-stroke depression'.
(14) The literature on depression and immunity is reviewed and the clinical implications of our findings are discussed.
(15) Subthreshold concentrations of the drug to induce complete blockade (5 x 10(-8)M) allowed to observe a greater depression of bioelectric cell characteristics in primary than in transitional fibres.
(16) However, a recrudescence in both psychotic and depressive symptoms developed as plasma desipramine levels rose 4 times higher than anticipated from the oral doses prescribed.
(17) These results indicate that the hormonal status should be taken into consideration in studies dealing with platelet MAO activity in depressed women.
(18) Three coyotes were operantly conditioned to depress one of two foot treadles, left or right, depending on the condition of the stimulus light.
(19) Although esmolol may be used as a primary hypotensive agent, the potential for marked myocardial depression must be recognized.
(20) Subjects who reported incidents of childhood sexual exploitation had lower levels of self-esteem and higher levels of depression than the comparison group.