(1) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(2) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(3) Symptoms, particularly colicky abdominal pain, improved during the period of chelation therapy.
(4) The present study explored the possibility that SOD-mimics such as desferrioxamine-Mn(III) chelate [DF-Mn] or cyclic nitroxide stable free radicals could protect from O2-.-independent damage.
(5) Chelators and sulfhydryl group reacting substances reduced the enzyme activity.
(6) Co2+ partially restored the activities lost by chelation.
(7) A chelator, dichloromethane diphosphonate (Cl2MDP), used to treat for malignancy-induced hypercalcemia, has nephrotoxic potential.
(8) This procedure, using mixed ligand chelate systems, may well be one which is limited to conditions more narrowly similar to those reported by Schubert and Derr (1978).
(9) Since the enzyme requires a metal ion (Co2+) we suggest that the RNA and heparin are inhibitory by virtue of their capacity to chelate the Co2+.
(10) Due to the higher stability constant, of MgCDTA, as compared to MgEDTA, addition of CDTA to a medium containing free Mg2+ and MgEDTA will not only chelate the free Mg2+, but it will also shift the equilibrium from MgEDTA towards MgCDTA, i.e.
(11) Their ability to inhibit iron-ion-dependent formation of .OH from H2O2 by chelating iron ions was also tested.
(12) The interest of monitoring lead excretion during chelation therapy is particularly emphasized.
(13) The data obtained testify to the presence in the granular fraction of the endopeptidase LTH-converting activity which is sensitive to pepstatin A, an aspartyl proteinase inhibitor as well as to chelators and a serine proteinase inhibitor.
(14) Chelation of extracellular calcium with ethyleneglycol-bis(beta-aminoethyl ether)N,N,N',N' tetraacetic acid (EGTA) did not abolish the increase in calcium.
(15) One was identified as viridomycin A, the ferrous chelate of 4-hydroxy-3-nitrosobenzaldehyde; the second (actinoviridin A) was the corresponding carboxylic acid chelate and the third (viridomycin E) was a hybrid chelate containing both the aldehyde and acid ligands.
(16) The ferrous iron chelator, bipyridyl, enhanced the production of chemiluminescence catalyzed by FeSO4 and ferritin but had little effect on the K3Fe(CN)6-catalyzed reaction.
(17) Kininase activity in the glomerulus and the proximal tubule was completely inhibited by chelating agents.
(18) Both enzymes are strongly inhibited by metal-chelating agents.
(19) Accumulated cysteine may chelate iron, accounting for the local increase in iron content in Hallervorden-Spatz disease.
(20) The efficiency of hydroxyl radical generation varied with the nature of the iron chelators used and increased in the order of phosphate alone approximately ADP less than EDTA less than diethylenetriaminepentaacetic acid (DETAPAC).
Remove
Definition:
(v. t.) To move away from the position occupied; to cause to change place; to displace; as, to remove a building.
(v. t.) To cause to leave a person or thing; to cause to cease to be; to take away; hence, to banish; to destroy; to put an end to; to kill; as, to remove a disease.
(v. t.) To dismiss or discharge from office; as, the President removed many postmasters.
(v. i.) To change place in any manner, or to make a change in place; to move or go from one residence, position, or place to another.
(n.) The act of removing; a removal.
(n.) The transfer of one's business, or of one's domestic belongings, from one location or dwelling house to another; -- in the United States usually called a move.
(n.) The state of being removed.
(n.) That which is removed, as a dish removed from table to make room for something else.
(n.) The distance or space through which anything is removed; interval; distance; stage; hence, a step or degree in any scale of gradation; specifically, a division in an English public school; as, the boy went up two removes last year.
(n.) The act of resetting a horse's shoe.
Example Sentences:
(1) Samples are hydrolyzed with Ba (OH)2, and the hydrolysate is passed through a Dowex-50 column to remove the salts and soluble carbohydrates.
(2) The Cavitron Ultrasonic Surgical Aspirator (CUSA) is a dissecting system that removes tissue by vibration, irrigation and suction; fluid and particulate matter from tumors are aspirated and subsquently deposited in a canister.
(3) After 3 and 6 months, blood collected by cardiocentesis using ether anesthesia and then sacrificed to remove CNS and internal organs.
(4) On removal of selective pressure, the His+ phenotype was lost more readily than the Ura+ Trp+ markers, with a corresponding decrease in plasmid copy number.
(5) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(6) Nine months later, the animals were sacrificed, the esophagus and the gastric stump were removed for histologic examination.
(7) Pain is not reported in the removal area, the clinical examinations show identical findings on both patellar tendons, X-ray and ultrasound evaluations do not demonstrate any change in patellar position.
(8) Decreased MU stops additions of bone by modeling and increases removal of bone next to marrow by remodeling.
(9) The International Monetary Fund, which has long urged Nigeria to remove the subsidy, supports the move.
(10) No effect of BSO pretreatments on the incomplete removal of crosslinks over 36 hr of observation was seen.
(11) Plasma for beta-endorphin assay was preincubated with sepharose-bound anti-beta-lipotropin to remove beta-lipotropin that cross-reacted with the beta-endorphin RIA.
(12) However in the deciduous teeth from which the successional tooth germs were removed, the processes of tooth resorption was very different in individuals, the difference between tooth resorption in normal occlusal force and in decreased occlusal force was not clear.
(13) A neonate without external malformation had undergone removal of a nasopharyngeal mass containing anterior and posterior pituitary tissue.
(14) Selective removal of endothelium had no effect on BK-induced contraction or the action of the antagonists.
(15) Conditions for limited digestion of the heterodimer by subtilisin, removing only the carboxyl terminus, were determined.
(16) Our recurrences are due to local infections, removing the metal strut too early, i.e.
(17) We conclude that removal of dimers and repair of gaps were similar in all cases.
(18) Solely infectious waste become removed hospital-intern and -extern on conditions of hygienic prevention, namely through secure packing during the transport, combustion or desinfection.
(19) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
(20) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.