(n.) A cartilaginous fish of several species, belonging to the order Holocephali. The teeth are few and large. The head is furnished with appendages, and the tail terminates in a point.
Example Sentences:
(1) A chimaera, called pCS200, which mediated expression of the CS1 or CS2 fimbrial antigen but not of CS3 fimbrial antigen in appropriate host strains, was obtained.
(2) In additional experiments, F1 to parental bone-marrow chimaeras were constructed such that the bone-marrow-derived cells and the non-bone-marrow-derived cells were of different RT-1 allotypes.
(3) Our motility analyses of the chimaeras confirmed that transplanted thoracic somitic mesoderm gives rise to brachial musculature and that the experimental muscles maintained the inherent dystrophic phenotype.
(4) Nevertheless, in a substantial proportion of chimaeras, OCs colonized derivatives of the ICM.
(5) These share a common placental circulation and hence develop as haematopoietic chimaeras.
(6) Results in a group of AKR reversible CBA leukaemia susceptible reversible resistant chimaeras suggest resistance is dominant.
(7) The [lpr----lpr] chimaeras were similar to untreated lpr mice.
(8) This leads to the total elimination of cell populations with one genotype, rat in particular in the mouse--rat chimaeras, or, possibly, to the sterility of the sheep--goat chimaeras.
(9) Germ-line transmission of the inactivated IGF-II gene from male chimaeras yielded heterozygous progeny that were smaller than their ES cell-derived wild-type littermates (about 60% of normal body weight).
(10) Plasmid pRB1, a representative chimaera carrying only the 3.3 kbp Sau3A fragment of pCB101, was successfully transferred from B. subtilis back to E. coli.
(11) Using the chick-quail chimaera technique we also studied the fate of each half-somite.
(12) By using the cytotoxic test, we found that both tolerant and nontolerant recipients were complete chimaeras, i.e., had only (C57BL x CBA-T6T6)F1 cells in their lymph nodes.
(13) Cell line SIKR-OSB resulted in one normal chimaera in 44 mice born.
(14) Two surgical embryo transfers to the chimaera resulted in pregnancies.
(15) The results demonstrate that the properties of protein domains are not always additive in a particular chimaera.
(16) Therefore, the possibility that the defect in development of P primitive ectoderms resided in their extra-embryonic tissues was investigated by analysing a series of chimaeras produced by injecting them into intact F blastocysts.
(17) Totally allogeneic chimaeras could be sensitized but only if given antigen in association with the appropriate Mph.
(18) The ultrastructure of T and B lymphocytes has been examined in long-term syngeneic chimaeras and age-control mice.
(19) delta-crystallin expression in these tissues is due to proper transcriptional regulation, since no expression was observed when chimaeras were produced with the ES lines carrying the mutant gene.
(20) Therefore, the lymphoid aplasia of [lpr----wild] radiation chimaeras does not result from an lpr graft-versus-host-like syndrome.
Chimera
Definition:
(n.) A monster represented as vomiting flames, and as having the head of a lion, the body of a goat, and the tail of a dragon.
(n.) A vain, foolish, or incongruous fancy, or creature of the imagination; as, the chimera of an author.
Example Sentences:
(1) The other chimeras accumulated in the plasma membrane, and truncated LEP100 was secreted.
(2) The bone marrow derivation of dThy-1+EC is now well established: dThy-1+EC carry Ly-5 determinants whose expression is restricted to cells of the hemopoietic differentiation pathway, and studies using Thy-1-disparate radiation bone marrow chimeras have revealed the presence of donor-type Thy-1+ cells within the epidermis; by immunoelectron microscopy, these cells represent dThy-1+EC.
(3) Complex I (19S) consists of gRNA, TUTase, RNA ligase and chimera-forming activity.
(4) Direct immunofluorescence tests for chicken IgG were positive in spinal cords of most SS chimeras but only of some LS chimeras.
(5) Tests on five different blood chimeras showed the T- and B-lymphocyte chimerism to be the same.
(6) The peak of GvH foci response occurred near the end of the 1st week when 70% of 950 R-RSp chimera spleens examined contained an average of 18 to 21 foci per spleen.
(7) In control chimeras, the mean ratio of the unlabeled cells:total chimera cell number (henceforth referred to as "mean ratio") was 0.50 with little or no weekly variation over the 9-week experimental period.
(8) Purified parental strain T cells prepared from unprimed chimeras were exposed to sheep erythrocytes in heavily irradiated mice of each of the two parental strains and recovered from thoracic duct lymph of the recipients at either day 1 or day 5 posttransfer.
(9) The quail-chick chimera method was used to examine whether neural crest cells were associated with the formation of semilunar valves.
(10) For this chimera, no residual [125I] hCG binding was observed in a range of 2 pM to 10 nM.
(11) All the bone marrow chimeras as well as allophenic mice with less than 20% Fv-2ss red cells failed to develop any of the symptoms of Friend disease after infection with the polycythemic strain of Friend virus.
(12) All surviving mice were complete donor-type chimeras.
(13) Highly increased survival was obtained for [B6 lpr----B6 nu, lpr] chimeras, but not for [B6+----B6 nu, lpr] and [B6 nu----B6 nu, lpr] chimeras.
(14) In chimeras the skin grafts of both parental types survive.
(15) The affinities of the anti-chimera antibodies for the B cell epitope were assessed by a fluid-phase double-isotope radioimmunoassay.
(16) The role of stimulated T cells in the induction of B mitoses was shown by (a) the incapacity of T-depleted spleen cells to be stimulated by PHA or in primary or secondary MLC, and (b) the restoration of the mitotic response of B cells to PHA by adding to the T cell-depleted culture either a very small number of T cell (identified by their different karyotype: "in vitro chimeras") or the cell-free supernatant of a 24 hr MLC.
(17) In contrast, chimeras made by reconstituting irradiated A mice with adult spleen cells of (A X B)F1 origin generate virus-specific cytotoxic activity for infected A and B targets, suggesting that mature T cells do not change their self-specificity readily.
(18) The resulting chimera can be expressed at high levels in Escherichia coli and is readily purified.
(19) The Chimera grid was used to avoid a grid with highly skewed cells.
(20) Complicating allogeneic effects were minimized or avoided by the use of helper T cells from normal F1 hybrids, parent leads to F1 chimeras, and F1 leads to parent chimeras.