(n.) A cartilaginous fish of several species, belonging to the order Holocephali. The teeth are few and large. The head is furnished with appendages, and the tail terminates in a point.
Example Sentences:
(1) A chimaera, called pCS200, which mediated expression of the CS1 or CS2 fimbrial antigen but not of CS3 fimbrial antigen in appropriate host strains, was obtained.
(2) In additional experiments, F1 to parental bone-marrow chimaeras were constructed such that the bone-marrow-derived cells and the non-bone-marrow-derived cells were of different RT-1 allotypes.
(3) Our motility analyses of the chimaeras confirmed that transplanted thoracic somitic mesoderm gives rise to brachial musculature and that the experimental muscles maintained the inherent dystrophic phenotype.
(4) Nevertheless, in a substantial proportion of chimaeras, OCs colonized derivatives of the ICM.
(5) These share a common placental circulation and hence develop as haematopoietic chimaeras.
(6) Results in a group of AKR reversible CBA leukaemia susceptible reversible resistant chimaeras suggest resistance is dominant.
(7) The [lpr----lpr] chimaeras were similar to untreated lpr mice.
(8) This leads to the total elimination of cell populations with one genotype, rat in particular in the mouse--rat chimaeras, or, possibly, to the sterility of the sheep--goat chimaeras.
(9) Germ-line transmission of the inactivated IGF-II gene from male chimaeras yielded heterozygous progeny that were smaller than their ES cell-derived wild-type littermates (about 60% of normal body weight).
(10) Plasmid pRB1, a representative chimaera carrying only the 3.3 kbp Sau3A fragment of pCB101, was successfully transferred from B. subtilis back to E. coli.
(11) Using the chick-quail chimaera technique we also studied the fate of each half-somite.
(12) By using the cytotoxic test, we found that both tolerant and nontolerant recipients were complete chimaeras, i.e., had only (C57BL x CBA-T6T6)F1 cells in their lymph nodes.
(13) Cell line SIKR-OSB resulted in one normal chimaera in 44 mice born.
(14) Two surgical embryo transfers to the chimaera resulted in pregnancies.
(15) The results demonstrate that the properties of protein domains are not always additive in a particular chimaera.
(16) Therefore, the possibility that the defect in development of P primitive ectoderms resided in their extra-embryonic tissues was investigated by analysing a series of chimaeras produced by injecting them into intact F blastocysts.
(17) Totally allogeneic chimaeras could be sensitized but only if given antigen in association with the appropriate Mph.
(18) The ultrastructure of T and B lymphocytes has been examined in long-term syngeneic chimaeras and age-control mice.
(19) delta-crystallin expression in these tissues is due to proper transcriptional regulation, since no expression was observed when chimaeras were produced with the ES lines carrying the mutant gene.
(20) Therefore, the lymphoid aplasia of [lpr----wild] radiation chimaeras does not result from an lpr graft-versus-host-like syndrome.
Ratfish
Definition:
(n.) Same as Rat-tail.
Example Sentences:
(1) Ratfish serum proteins have been fractionated by ammonium sulfate, followed by gel filtration on Sepharose 6B.
(2) Elephantfish and pig glucagons differ at only four positions, but there are six changes from the ratfish glucagon-36 (normal glucagon contains 29 residues) sequence.
(3) Brain extract from the spotted ratfish, Hydrolagus colliei, contains gonadotropin-releasing hormone (GnRH)-like peptides in both sexes.
(4) Sertoli cells in the ratfish entirely surround a clone of spermatids to form a spermatocyst.
(5) A potent, highly selective bombesin receptor antagonist completely abolished the stimulation of amylase release caused by the ratfish peptide, demonstrating the specificity of the response.
(6) A highly purified bombesin-like peptide-containing fraction stimulated amylase release in a dose-responsive fashion from rat pancreatic acini; the dose-response curve was parallel to a bombesin standard, and the ratfish peptide stimulated the same maximal rate of amylase secretion as the bombesin standard.
(7) The primary structure of insulin from the Holocephalan fish, Hydrolagus colliei (the ratfish), has been established by automated Edman degradation as: (Formula: see text).
(8) The presence of a COOH-terminal extension to the B-chain is consistent with the occurrence of a single base mutation in the region of the gene encoding one of the dibasic residue processing sites [Arg31(AGA)----Ile* (AUA)] with the result that the ratfish has utilised an alternative cleavage site within the C-peptide region of proinsulin.
(9) Two molecular forms of glucagon-like peptide were isolated from the ratfish pancreas.
(10) A 36-amino-acid-residue peptide was isolated from the pancreas of a holocephalan fish, the Pacific ratfish (Hydrolagus colliei), that shows homology (69%) to mammalian glucagon in its N-terminal region and is reactive towards an N-terminally directed antiserum.
(11) Spermiogenesis in the ratfish (Hydrolagus colliei) is characterized by unusual changes in the basic proteins of the nucleus.
(12) Ratfish (Hydrolagus colliei) intestines were boiled in water to inactivate proteases and then treated with cold 4% trifluoroacetic acid to extract bombesin-like peptides.
(13) Pituitary extracts from all animals, except the ratfish, goldfish and trout, contained IR-CGRP.
(14) The ratfish represents the most primitive organism that contains a form of GnRH that coelutes with chicken II and salmon II GnRH.
(15) The insulin B-chain contains 31 residues, one more than mammalian insulins, but markedly less than that of the closely related ratfish with which it otherwise exhibits high sequence similarity.
(16) The insulin with 38 amino acids in the B-chain was equipotent with human insulin in inhibiting the binding of radiolabelled human insulin to rat fat cells but the maximum effect of ratfish insulin upon the transport of 3-O-methylglucose into the cells was only 65% of the maximum effect of human insulin.
(17) In contrast to the heavy chain, the ratfish light chains display low sequence similarity with their shark kappa counterparts.
(18) It is argued that the ratfish GnRH molecule has been retained for over 400 million years of evolution and is expressed in most vertebrate classes.
(19) The amino acid compositions of both rabbit fish and ratfish insulins demonstrated a value consistently lower than that expected for the leucine content of the peptides.
(20) Gonadotropin-releasing hormone (GnRH) in the ratfish brain has been isolated and purified using reverse-phase high performance liquid chromatography.