(1) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(2) The results suggests that abrin B chain of chimeric protein may act as a vector to carry ACTI into the tumor cells.
(3) ch14.18-delta CH2 was localized to the melanoma tumors more rapidly and with better localization ratios than the intact chimeric antibody ch14.18.
(4) Using a cell line as a model, it was found that the CD38 antigen acts as a target for a chimeric antibody prepared from the antibody OKT10.
(5) Chimeric plasmids pCD1 and pCD3 were constructed from site-specific endonuclease digests of bacteriophage phi3T DNA cloned in pMB9 in E. coli.
(6) The chimeric antibodies studied have several advantages over human paraproteins as quality control reagents for clinical assays.
(7) The ability to generate reconstructed antibodies, chimeric antibodies, catalytic antibodies and the use of modelled antibodies for the design of drugs is discussed.
(8) In another transgenic strain, carrying the rat MLC2 gene and a modified rat skeletal muscle actin gene (actin-globin chimeric gene), transcripts of the rat MLC2 gene were detected in skeletal muscle only, whereas the actin-globin transcripts were detected in skeletal muscle as well as in the heart.
(9) Chimeric oligodeoxynucleotides, comprised of internal phosphodiester and terminal methylphosphonodiester sections, possess many beneficial characteristics as antisense effectors.
(10) The chimeric shuttle vector was transformed into strain GS-5, and two transformants (TK15 and TK18) were isolated.
(11) In typical applications like the differentiation of cells derived from chimeric animals or the characterization of chromosomes in somatic cell hybrids, the two DNA probes are differently labeled and detected using label-specific reagents that fluoresce at different wavelengths.
(12) An insulin response element (IRE) has been identified in the prolactin gene using chimeric plasmids in which prolactin promoter DNA directs expression of the bacterial chloramphenicol acetyltransferase gene.
(13) Fusion of 90 amino acids of HIV-1 Gag protein to HBcAg still allowed the formation of capsids presenting on their surface epitopes of HIV-1 core protein, whereas fusion of 317, 189, or 100 amino acids of Gag prevented self-assembly of chimeric particles.
(14) K12G0S32 is a 57-kDa recombinant single-chain chimeric plasminogen activator consisting of scFv-K12Go, a single-chain variable-region antigen-binding fragment (Fv) of the monoclonal antibody MA-15C5, which is specific for fragment D-dimer of human cross-linked fibrin, and a low-molecular-mass (33 kDa) urokinase-type plasminogen activator (u-PA-33k) containing amino acids Ala132-Leu411 (Holvoet, P., Laroche, Y., Lijnen, H. R., Van Cauwenberghe, R., Demarsin, E., Brouwers, E., Matthyssens, G. & Collen D. (1991) J. Biol.
(15) The chimeric protein produced by expression of this plasmid has been isolated and then cleaved by the enteropeptidase to give [Leu5]enkephalin with the yield 74%.
(16) Tests on five different blood chimeras showed the T- and B-lymphocyte chimerism to be the same.
(17) To understand the regulation of expression of these two genes, we fused the 5'-flanking region to the CAT gene in inverted orientations to generate two chimeric plasmids, pH3-II-900 and pH3-III-900.
(18) In this study, we describe biochemical, serological, immunohistochemical, and functional properties of the chimeric ING-1 antibody.
(19) Using DNA restriction-fragment-length polymorphisms (RFLPs), we have evaluated the feasibility of developing a single synthetic oligonucleotide probe to study post-BMT chimerism.
(20) Some chimeric genes did not accumulate outer membrane proteins, despite the fact that the fusion of the ompF and ompC genes was in frame.
Ring
Definition:
(v. t.) To cause to sound, especially by striking, as a metallic body; as, to ring a bell.
(v. t.) To make (a sound), as by ringing a bell; to sound.
(v. t.) To repeat often, loudly, or earnestly.
(v. i.) To sound, as a bell or other sonorous body, particularly a metallic one.
(v. i.) To practice making music with bells.
(v. i.) To sound loud; to resound; to be filled with a ringing or reverberating sound.
(v. i.) To continue to sound or vibrate; to resound.
(v. i.) To be filled with report or talk; as, the whole town rings with his fame.
(n.) A sound; especially, the sound of vibrating metals; as, the ring of a bell.
(n.) Any loud sound; the sound of numerous voices; a sound continued, repeated, or reverberated.
(n.) A chime, or set of bells harmonically tuned.
(n.) A circle, or a circular line, or anything in the form of a circular line or hoop.
(n.) Specifically, a circular ornament of gold or other precious material worn on the finger, or attached to the ear, the nose, or some other part of the person; as, a wedding ring.
(n.) A circular area in which races are or run or other sports are performed; an arena.
(n.) An inclosed space in which pugilists fight; hence, figuratively, prize fighting.
(n.) A circular group of persons.
(n.) The plane figure included between the circumferences of two concentric circles.
(n.) The solid generated by the revolution of a circle, or other figure, about an exterior straight line (as an axis) lying in the same plane as the circle or other figure.
(n.) An instrument, formerly used for taking the sun's altitude, consisting of a brass ring suspended by a swivel, with a hole at one side through which a solar ray entering indicated the altitude on the graduated inner surface opposite.
(n.) An elastic band partly or wholly encircling the spore cases of ferns. See Illust. of Sporangium.
(n.) A clique; an exclusive combination of persons for a selfish purpose, as to control the market, distribute offices, obtain contracts, etc.
(v. t.) To surround with a ring, or as with a ring; to encircle.
(v. t.) To make a ring around by cutting away the bark; to girdle; as, to ring branches or roots.
(v. t.) To fit with a ring or with rings, as the fingers, or a swine's snout.
(v. i.) To rise in the air spirally.
Example Sentences:
(1) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(2) Sterile, pruritic papules and papulopustules that formed annular rings developed on the back of a 58-year-old woman.
(3) The teeth were embedded in phenolic rings with acrylic resin.
(4) Surgical removal was avoided without complications by detaching it with a ring stripper.
(5) The Labour MP urged David Cameron to guarantee that officers who give evidence over the alleged paedophile ring in Westminster will not be prosecuted.
(6) These results coupled with previous studies support activation of benz[j]aceanthrylene via both 2 and cyclopenta ring epoxidation.
(7) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(8) Endothelium-dependent relaxations to acetylcholine and endothelium-independent relaxations to nitric oxide were observed in rings from both strains during contraction with endothelin.
(9) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
(10) The intracellular distribution and interaction of 19S ring-type particles from D. melanogaster have been analysed.
(11) Rings of isolated coronary and femoral arteries (without endothelium) were suspended for isometric tension recording in organ chambers filled with modified Krebs-Ringer bicarbonate solution.
(12) In all cases Richter's hernia was at the internal inguinal ring.
(13) Seventy-five hands showed normal distal latency, in which cases, however, the SNCV of the ring finger was always outside the normal range, while the SNCVs of the thumb, index and middle fingers were abnormal in 64%, 80% and 92% of cases respectively.
(14) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(15) Defects in the posterior one-half of the trachea, up to 5 rings long, were repaired, with minimal stenosis.
(16) A new analog of salmon calcitonin (N alpha-propionyl Di-Ala1,7,des-Leu19 sCT; RG-12851; here termed CTR), which lacks the ring structure of native calcitonin, was tested for biological activity in several in vitro and in vivo assay systems.
(17) The chemical shift changes observed on the binding of trimethoprim to dihydrofolate reductase are interpreted in terms of the ring-current shift contributions from the two aromatic rings of trimethoprim and from that of phenylalanine-30.
(18) Three strains of fluorescent pseudomonads (IS-1, IS-2, and IS-3) isolated from potato underground stems with roots showed in vitro antibiosis against 30 strains of the ring rot bacterium Clavibacter michiganensis subsp.
(19) Both adiphenine.HCl and proadifen.HCl form more stable complexes, suggesting that hydrogen bonding to the carbonyl oxygen by the hydroxyl-group on the rim of the CD ring could be an important contributor to the complexation.
(20) Serial sections from over a hundred such structures show that these are tubular structures and that the 'test-tube and ring-shaped' forms described in the literature are no more than profiles one expects to see when a tubular structure is sectioned.