(n.) A monster represented as vomiting flames, and as having the head of a lion, the body of a goat, and the tail of a dragon.
(n.) A vain, foolish, or incongruous fancy, or creature of the imagination; as, the chimera of an author.
Example Sentences:
(1) The other chimeras accumulated in the plasma membrane, and truncated LEP100 was secreted.
(2) The bone marrow derivation of dThy-1+EC is now well established: dThy-1+EC carry Ly-5 determinants whose expression is restricted to cells of the hemopoietic differentiation pathway, and studies using Thy-1-disparate radiation bone marrow chimeras have revealed the presence of donor-type Thy-1+ cells within the epidermis; by immunoelectron microscopy, these cells represent dThy-1+EC.
(3) Complex I (19S) consists of gRNA, TUTase, RNA ligase and chimera-forming activity.
(4) Direct immunofluorescence tests for chicken IgG were positive in spinal cords of most SS chimeras but only of some LS chimeras.
(5) Tests on five different blood chimeras showed the T- and B-lymphocyte chimerism to be the same.
(6) The peak of GvH foci response occurred near the end of the 1st week when 70% of 950 R-RSp chimera spleens examined contained an average of 18 to 21 foci per spleen.
(7) In control chimeras, the mean ratio of the unlabeled cells:total chimera cell number (henceforth referred to as "mean ratio") was 0.50 with little or no weekly variation over the 9-week experimental period.
(8) Purified parental strain T cells prepared from unprimed chimeras were exposed to sheep erythrocytes in heavily irradiated mice of each of the two parental strains and recovered from thoracic duct lymph of the recipients at either day 1 or day 5 posttransfer.
(9) The quail-chick chimera method was used to examine whether neural crest cells were associated with the formation of semilunar valves.
(10) For this chimera, no residual [125I] hCG binding was observed in a range of 2 pM to 10 nM.
(11) All the bone marrow chimeras as well as allophenic mice with less than 20% Fv-2ss red cells failed to develop any of the symptoms of Friend disease after infection with the polycythemic strain of Friend virus.
(12) All surviving mice were complete donor-type chimeras.
(13) Highly increased survival was obtained for [B6 lpr----B6 nu, lpr] chimeras, but not for [B6+----B6 nu, lpr] and [B6 nu----B6 nu, lpr] chimeras.
(14) In chimeras the skin grafts of both parental types survive.
(15) The affinities of the anti-chimera antibodies for the B cell epitope were assessed by a fluid-phase double-isotope radioimmunoassay.
(16) The role of stimulated T cells in the induction of B mitoses was shown by (a) the incapacity of T-depleted spleen cells to be stimulated by PHA or in primary or secondary MLC, and (b) the restoration of the mitotic response of B cells to PHA by adding to the T cell-depleted culture either a very small number of T cell (identified by their different karyotype: "in vitro chimeras") or the cell-free supernatant of a 24 hr MLC.
(17) In contrast, chimeras made by reconstituting irradiated A mice with adult spleen cells of (A X B)F1 origin generate virus-specific cytotoxic activity for infected A and B targets, suggesting that mature T cells do not change their self-specificity readily.
(18) The resulting chimera can be expressed at high levels in Escherichia coli and is readily purified.
(19) The Chimera grid was used to avoid a grid with highly skewed cells.
(20) Complicating allogeneic effects were minimized or avoided by the use of helper T cells from normal F1 hybrids, parent leads to F1 chimeras, and F1 leads to parent chimeras.
Fusion
Definition:
(v. t.) The act or operation of melting or rendering fluid by heat; the act of melting together; as, the fusion of metals.
(v. t.) The state of being melted or dissolved by heat; a state of fluidity or flowing in consequence of heat; as, metals in fusion.
(v. t.) The union or blending together of things, as, melted together.
(v. t.) The union, or binding together, of adjacent parts or tissues.
Example Sentences:
(1) To identify the NHE-1 protein and to establish its cellular and subcellular localization in the rabbit kidney, we prepared antibodies to a NHE-1 fusion protein.
(2) Three criteria of fusion ventricular complexes were found to be undiagnostic for right and left ventricular complexes in SVE.
(3) Furthermore, these data support our previous suggestion that the expression of human lymphoid differentiation antigens in human-mouse lymphoid hybrids is influenced by the differentiation stage of the fusion partners.
(4) Several technical advantages of this method of fusion make this approach particularly useful in patients with rheumatoid arthritis.
(5) These differences point to the fact that the mechanisms that regulate satellite cell mitotic and fusion behavior are also not the same in all muscles.
(6) Expansion of the cell sheet following attachment, and the fusion of epiblasts advancing toward each other, does not require the presence of mineralocorticoid.
(7) The ophthalmic headache's crisis is caused, in fact, by a spasm of convergence on an unknown exophory of which the amplitude of fusion is satisfying, and the presence of which can only be seen with test under screen.
(8) In the companion paper, we quantitatively account for the observation that the ability of a solute to promote fusion depends on its permeability properties and the method of swelling.
(9) Opsin becomes incorporated into the disk membrane by a process of membrane expansion and fusion to form the flattened disks of the outer segment.
(10) One mutant, BS260, was completely noninvasive on HeLa cells and mapped to a region on the 220-kb virulence plasmid in which we had previously localized several avirulent temperature-regulated operon fusions (A.E.
(11) Using a soluble ICAM-2 Ig fusion protein (receptor globulin, Rg) we demonstrate the costimulatory effect of ICAM-2 during the activation of CD4+ T cells.
(12) With thermosensitive mutants non-defective for G and M antigens, cell fusion is much more extensive at the non-permissive temperature (39-6 degrees C) than at the permissive one (31 degrees C).
(13) This suggests that the fusion protein traps the SII in nonstimulatory interactions and that antibody 2-7B inhibits SII binding to RNA polymerase II.
(14) Ca2+ has a central role in various cellular phenomena involving membrane fusion.
(15) Polypeptides of egg-borne Sendai virus (egg Sendai), which is biologically active on the basis of criteria of the infectivity for L cells and of hemolytic and cell fusion activities, were compared by polyacrylamide gel electrophoresis with those of L cell-borne (L Sendai) and HeLa cell-borne Sendai (HeLa Sendai) viruses, which are judged biologically inactive by the above criteria.
(16) Pulse-chase experiments showed that the ornithine transcarbamylase precursor and the thiolase traveled from the cytosol to the mitochondria with half-lives of less than 5 min, whereas the three fusion proteins traveled with half-lives of 10-15 min.
(17) The results of this study suggest that the effects of benzylated CD4(81-92) derivatives on HIV-1 binding or fusion should not be used to reach conclusions about the function of the corresponding CD4 region.
(18) Construction of a repR-lacZ fusion proved that the increase in copy number was due to a proportional increase in the amount of RepR protein.
(19) The best understood fusion mechanism is that of influenza virus, for which sequences involved in pH-dependent fusion can be correlated with the crystallographic structure of the spike protein.
(20) The fusion protein is incorporated into the virion, which retains infectivity and displays the foreign amino acids in immunologically accessible form.