(n.) A monster represented as vomiting flames, and as having the head of a lion, the body of a goat, and the tail of a dragon.
(n.) A vain, foolish, or incongruous fancy, or creature of the imagination; as, the chimera of an author.
Example Sentences:
(1) The other chimeras accumulated in the plasma membrane, and truncated LEP100 was secreted.
(2) The bone marrow derivation of dThy-1+EC is now well established: dThy-1+EC carry Ly-5 determinants whose expression is restricted to cells of the hemopoietic differentiation pathway, and studies using Thy-1-disparate radiation bone marrow chimeras have revealed the presence of donor-type Thy-1+ cells within the epidermis; by immunoelectron microscopy, these cells represent dThy-1+EC.
(3) Complex I (19S) consists of gRNA, TUTase, RNA ligase and chimera-forming activity.
(4) Direct immunofluorescence tests for chicken IgG were positive in spinal cords of most SS chimeras but only of some LS chimeras.
(5) Tests on five different blood chimeras showed the T- and B-lymphocyte chimerism to be the same.
(6) The peak of GvH foci response occurred near the end of the 1st week when 70% of 950 R-RSp chimera spleens examined contained an average of 18 to 21 foci per spleen.
(7) In control chimeras, the mean ratio of the unlabeled cells:total chimera cell number (henceforth referred to as "mean ratio") was 0.50 with little or no weekly variation over the 9-week experimental period.
(8) Purified parental strain T cells prepared from unprimed chimeras were exposed to sheep erythrocytes in heavily irradiated mice of each of the two parental strains and recovered from thoracic duct lymph of the recipients at either day 1 or day 5 posttransfer.
(9) The quail-chick chimera method was used to examine whether neural crest cells were associated with the formation of semilunar valves.
(10) For this chimera, no residual [125I] hCG binding was observed in a range of 2 pM to 10 nM.
(11) All the bone marrow chimeras as well as allophenic mice with less than 20% Fv-2ss red cells failed to develop any of the symptoms of Friend disease after infection with the polycythemic strain of Friend virus.
(12) All surviving mice were complete donor-type chimeras.
(13) Highly increased survival was obtained for [B6 lpr----B6 nu, lpr] chimeras, but not for [B6+----B6 nu, lpr] and [B6 nu----B6 nu, lpr] chimeras.
(14) In chimeras the skin grafts of both parental types survive.
(15) The affinities of the anti-chimera antibodies for the B cell epitope were assessed by a fluid-phase double-isotope radioimmunoassay.
(16) The role of stimulated T cells in the induction of B mitoses was shown by (a) the incapacity of T-depleted spleen cells to be stimulated by PHA or in primary or secondary MLC, and (b) the restoration of the mitotic response of B cells to PHA by adding to the T cell-depleted culture either a very small number of T cell (identified by their different karyotype: "in vitro chimeras") or the cell-free supernatant of a 24 hr MLC.
(17) In contrast, chimeras made by reconstituting irradiated A mice with adult spleen cells of (A X B)F1 origin generate virus-specific cytotoxic activity for infected A and B targets, suggesting that mature T cells do not change their self-specificity readily.
(18) The resulting chimera can be expressed at high levels in Escherichia coli and is readily purified.
(19) The Chimera grid was used to avoid a grid with highly skewed cells.
(20) Complicating allogeneic effects were minimized or avoided by the use of helper T cells from normal F1 hybrids, parent leads to F1 chimeras, and F1 leads to parent chimeras.
Ratfish
Definition:
(n.) Same as Rat-tail.
Example Sentences:
(1) Ratfish serum proteins have been fractionated by ammonium sulfate, followed by gel filtration on Sepharose 6B.
(2) Elephantfish and pig glucagons differ at only four positions, but there are six changes from the ratfish glucagon-36 (normal glucagon contains 29 residues) sequence.
(3) Brain extract from the spotted ratfish, Hydrolagus colliei, contains gonadotropin-releasing hormone (GnRH)-like peptides in both sexes.
(4) Sertoli cells in the ratfish entirely surround a clone of spermatids to form a spermatocyst.
(5) A potent, highly selective bombesin receptor antagonist completely abolished the stimulation of amylase release caused by the ratfish peptide, demonstrating the specificity of the response.
(6) A highly purified bombesin-like peptide-containing fraction stimulated amylase release in a dose-responsive fashion from rat pancreatic acini; the dose-response curve was parallel to a bombesin standard, and the ratfish peptide stimulated the same maximal rate of amylase secretion as the bombesin standard.
(7) The primary structure of insulin from the Holocephalan fish, Hydrolagus colliei (the ratfish), has been established by automated Edman degradation as: (Formula: see text).
(8) The presence of a COOH-terminal extension to the B-chain is consistent with the occurrence of a single base mutation in the region of the gene encoding one of the dibasic residue processing sites [Arg31(AGA)----Ile* (AUA)] with the result that the ratfish has utilised an alternative cleavage site within the C-peptide region of proinsulin.
(9) Two molecular forms of glucagon-like peptide were isolated from the ratfish pancreas.
(10) A 36-amino-acid-residue peptide was isolated from the pancreas of a holocephalan fish, the Pacific ratfish (Hydrolagus colliei), that shows homology (69%) to mammalian glucagon in its N-terminal region and is reactive towards an N-terminally directed antiserum.
(11) Spermiogenesis in the ratfish (Hydrolagus colliei) is characterized by unusual changes in the basic proteins of the nucleus.
(12) Ratfish (Hydrolagus colliei) intestines were boiled in water to inactivate proteases and then treated with cold 4% trifluoroacetic acid to extract bombesin-like peptides.
(13) Pituitary extracts from all animals, except the ratfish, goldfish and trout, contained IR-CGRP.
(14) The ratfish represents the most primitive organism that contains a form of GnRH that coelutes with chicken II and salmon II GnRH.
(15) The insulin B-chain contains 31 residues, one more than mammalian insulins, but markedly less than that of the closely related ratfish with which it otherwise exhibits high sequence similarity.
(16) The insulin with 38 amino acids in the B-chain was equipotent with human insulin in inhibiting the binding of radiolabelled human insulin to rat fat cells but the maximum effect of ratfish insulin upon the transport of 3-O-methylglucose into the cells was only 65% of the maximum effect of human insulin.
(17) In contrast to the heavy chain, the ratfish light chains display low sequence similarity with their shark kappa counterparts.
(18) It is argued that the ratfish GnRH molecule has been retained for over 400 million years of evolution and is expressed in most vertebrate classes.
(19) The amino acid compositions of both rabbit fish and ratfish insulins demonstrated a value consistently lower than that expected for the leucine content of the peptides.
(20) Gonadotropin-releasing hormone (GnRH) in the ratfish brain has been isolated and purified using reverse-phase high performance liquid chromatography.