(a.) Merely imaginary; fanciful; fantastic; wildly or vainly conceived; having, or capable of having, no existence except in thought; as, chimerical projects.
Example Sentences:
(1) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(2) The results suggests that abrin B chain of chimeric protein may act as a vector to carry ACTI into the tumor cells.
(3) ch14.18-delta CH2 was localized to the melanoma tumors more rapidly and with better localization ratios than the intact chimeric antibody ch14.18.
(4) Using a cell line as a model, it was found that the CD38 antigen acts as a target for a chimeric antibody prepared from the antibody OKT10.
(5) Chimeric plasmids pCD1 and pCD3 were constructed from site-specific endonuclease digests of bacteriophage phi3T DNA cloned in pMB9 in E. coli.
(6) The chimeric antibodies studied have several advantages over human paraproteins as quality control reagents for clinical assays.
(7) The ability to generate reconstructed antibodies, chimeric antibodies, catalytic antibodies and the use of modelled antibodies for the design of drugs is discussed.
(8) In another transgenic strain, carrying the rat MLC2 gene and a modified rat skeletal muscle actin gene (actin-globin chimeric gene), transcripts of the rat MLC2 gene were detected in skeletal muscle only, whereas the actin-globin transcripts were detected in skeletal muscle as well as in the heart.
(9) Chimeric oligodeoxynucleotides, comprised of internal phosphodiester and terminal methylphosphonodiester sections, possess many beneficial characteristics as antisense effectors.
(10) The chimeric shuttle vector was transformed into strain GS-5, and two transformants (TK15 and TK18) were isolated.
(11) In typical applications like the differentiation of cells derived from chimeric animals or the characterization of chromosomes in somatic cell hybrids, the two DNA probes are differently labeled and detected using label-specific reagents that fluoresce at different wavelengths.
(12) An insulin response element (IRE) has been identified in the prolactin gene using chimeric plasmids in which prolactin promoter DNA directs expression of the bacterial chloramphenicol acetyltransferase gene.
(13) Fusion of 90 amino acids of HIV-1 Gag protein to HBcAg still allowed the formation of capsids presenting on their surface epitopes of HIV-1 core protein, whereas fusion of 317, 189, or 100 amino acids of Gag prevented self-assembly of chimeric particles.
(14) K12G0S32 is a 57-kDa recombinant single-chain chimeric plasminogen activator consisting of scFv-K12Go, a single-chain variable-region antigen-binding fragment (Fv) of the monoclonal antibody MA-15C5, which is specific for fragment D-dimer of human cross-linked fibrin, and a low-molecular-mass (33 kDa) urokinase-type plasminogen activator (u-PA-33k) containing amino acids Ala132-Leu411 (Holvoet, P., Laroche, Y., Lijnen, H. R., Van Cauwenberghe, R., Demarsin, E., Brouwers, E., Matthyssens, G. & Collen D. (1991) J. Biol.
(15) The chimeric protein produced by expression of this plasmid has been isolated and then cleaved by the enteropeptidase to give [Leu5]enkephalin with the yield 74%.
(16) Tests on five different blood chimeras showed the T- and B-lymphocyte chimerism to be the same.
(17) To understand the regulation of expression of these two genes, we fused the 5'-flanking region to the CAT gene in inverted orientations to generate two chimeric plasmids, pH3-II-900 and pH3-III-900.
(18) In this study, we describe biochemical, serological, immunohistochemical, and functional properties of the chimeric ING-1 antibody.
(19) Using DNA restriction-fragment-length polymorphisms (RFLPs), we have evaluated the feasibility of developing a single synthetic oligonucleotide probe to study post-BMT chimerism.
(20) Some chimeric genes did not accumulate outer membrane proteins, despite the fact that the fusion of the ompF and ompC genes was in frame.
Zany
Definition:
(n.) A merry-andrew; a buffoon.
(v. t.) To mimic.
Example Sentences:
(1) There’s a plausible view , however, that these extreme positions are not so much sincere commitments as zany weather balloons, floated to see how well they play with the public, as well as to bamboozle his Republican opponents.
(2) There are, he said, “quite a lot of letters and they say some things that are quite zany”.
(3) But nobody ought really to have been surprised because this, after all, is Van Gaal; the king of zaniness and over-the-top outpourings, not to mention latent hostility towards the media.
(4) One of Williams’ final films will be Absolutely Anything, a zany sci-fi comedy starring the Monty Python team alongside Simon Pegg, with Williams voicing a dog.
(5) They are a strange team right now, an end-of-era affair, with a zany, depleted defence and genuine craft and edge elsewhere.
(6) His zany guitar bodies are created using computer-aided design (CAD) software , output in one piece on an EOS 3D printer.
(7) The tone of the game is quite different to previous installments in that a good deal of the zany humour has been drained completely.
(8) On a ITV sofa show this week Corbyn was lured into discussing what he calls his “zany” interest in drains.
(9) The Qatari Armed Forces Investment Portfolio's representative, General Zani al Kuwari, who is also assistant chief of staff for financial affairs, said: "Our objective is to invest in the most important cities, and Barcelona is one of them.
(10) But Texas senator Ted Cruz and Jeb Bush , usually considered a moderate among the zany Republican field, took it a step further: they urged that only Syrian Christians be allowed to come to America as refugees.
(11) Culture A bunch of Mayan villagers are hanging out in the jungle, improbably hunting big game with a zany Indiana Jones-style contraption that looks like a giant sideways meat tenderiser.
(12) For a serious discussion of a subject like this to be granted so much time on British television, where the bulk of wine talk has to be aggressively crammed around the fringes of weekend morning food shows – and even then only so long as the wine expert agrees to spend most of their time on air pulling funny faces and making endless zany ‘zoinks-a-lummy’ proclamations – is extraordinary.
(13) Their humour is zany, beguiling and incongruous: the cast includes a chatty moon, a talking ape and a tiny shaman called Naboo played by Fielding's brother.
(14) Shortly afterwards, citing Rock as a precedent, a Texas Court of Appeals admitted the hypnotically elicited testimony of an eyewitness in Zani v. State (1988), on the grounds that it would be unfair to admit the hypnotically elicited testimony of defendants, and proscribe it for victims and witnesses.
(15) Photograph: Niko Kitsakis I'd been looking forward to browsing the shelves for zany gadgets, but the reality was slightly disappointing.
(16) That zany guy who constantly spouts hilarious zingers on Twitter ?
(17) At a time of crisis it is not about one’s “zany” love of drains, of which more later.
(18) Particularly having wasted a lot of time dealing with a lot of zany, ideological gimmicks from Michael Gove and his team, it would be a good thing if the Liberal Democrats were able to run education policy on our own terms,” he said.
(19) This was a departure from his usual zany-bonkers output, presumably causing millions of listeners to start rifling through the medicine cabinet and cueing up the scene featuring Basil Fawlty thrashing his car with a branch for themselves.
(20) Instead, somehow or other, he has come into possession of a preternaturally phantasmagoric suit of armour, complete with zany high-tech accoutrements; or a hammer that can call down lightning from the heavens; or extendable fingernails; or laser eyesight; or implausible (and non-steroid-related) abs; or the ability to change shape.