(n.) A colorless volatile liquid, CHCl3, having an ethereal odor and a sweetish taste, formed by treating alcohol with chlorine and an alkali. It is a powerful solvent of wax, resin, etc., and is extensively used to produce anaesthesia in surgical operations; also externally, to alleviate pain.
(v. t.) To treat with chloroform, or to place under its influence.
Example Sentences:
(1) It was readily soluble, however, in nonpolar solvents such as n-hexane and chloroform.
(2) Homogenates of these cells in chloroform-methanol solution showed an identical absorption spectrum with pure bilirubin dissolved in the same solution.
(3) Male and female DBA 11 mice recovered from 1 hr of anesthesia with chloroform of fluoroxene apparently unharmed.
(4) After introduction of surgical anesthesia with general agents such as ether and chloroform, a large number of deaths due to anesthetic toxicity were reported.
(5) One was best soluble in modified chloroform-methanol-water mixture (10:10:3) and corresponded most probably to the oligosaccharyl disphosphodolichol (oligo-PP-Dol) described to be significantly increased in LPs of inherited type.
(6) The methanol-ammonia (20:1) and chloroform-methanol-ammonia (2:2:1) systems, used with silica-gel plates, are the most promising for rapid preliminary screening of tuna fish extracts for histamine.
(7) Mice administered chloroform in corn oil displayed a significant degree of diffuse parenchymal degeneration (5 of 10 males and 1 of 10 females) and mild to moderate early cirrhosis (5 of 10 males and 9 of 10 females); significant pathological lesions were not observed in the animals administered corn oil without chloroform nor in mice receiving chloroform in 2% Emulphor.
(8) When citrate was reacted with HOCl, beta-ketoglutaric acid, monochloroacetone, dichloroacetone, and trichloroacetone were produced as reaction intermediates and chloroform as a final product.
(9) A methanol-aqueous KCl extraction is used, followed by cleanup with clarifying agents and partition into chloroform.
(10) An almost pure form of the bovine heart mitochondrial adenosine triphosphatase (ATPase) is released from the membrane by shaking submitochondrial particles with chloroform.
(11) The use of a chloroform:methanol extraction of 10 ml of fluid resulted in recoveries of at least 90% of the glycosaminoglycans, otherwise an insoluble product resulted.
(12) The primary finding was that chloroform increased the yield of renal tubular adenomas and adenocarcinomas in male rats in a dose-related manner.
(13) Three new euglobals with acylphloroglucinol-monoterpene structures, named euglobal -G1 (1), -G2 (2), and -G3 (3) were isolated from the chloroform extract of the juvenile leaves of Eucalyptus grandis (Myrtaceae).
(14) However, the concentration of endotoxin in whole blood and platelet-rich plasma could be measured with this Limulus test after lysing the platelets to release the endotoxin and subsequently removing the inhibitory proteins by chloroform precipitation.
(15) The ethanolic extract from rat liver mitochondrial membranes contains a number of highly polar complex lipids, which are found in the aqueous layer when subjected to the usual chloroform-water partition procedures.
(16) Addition of chloroform and molybdate caused an accumulation of cold acetate in large sediment cores and of [14C]acetate in small cores to which [14C]bicarbonate had been added.
(17) A variety of protected peptides up to tetradecapeptides have been chromatographed at pressures of 50 to 150 psi and obtained in analytically pure from within 2 to 4 h. With such commonly used protecting groups as N-benzyloxycarbonyl (Z), N-2-(p-biphenylyl)-2-propyloxycarbonyl (Bpoc), N-t-butyloxycarbonyl (Boc), O- and S-t-butyl (But), and S-acetamidomethyl (Acm), compounds were sufficiently soluble in chloroform, alcohols, acetic acid, or mixtures of these solvents for column loading.
(18) Both 31Si and 68Ge were water extractable (47%-74% and 38%-89%, respectively) from liver cell organelles; 45%-81% 31Si and 66%-90% 68Ge were extractable in 10% TCA, while only 10%-59% of either isotope were extractable in organic solvents (acetone, chloroform, ethanol).
(19) The mobile phase consisted of a high percentage of methanol or acetonitrile with a small amount of chloroform.
(20) Treatment of this ketone with either phenyllithium or phenylamagnesium bromide in ether at room temperature followed by solvolysis of the resulting alcohol in a mixture of trifluoroacetic acid, sodium azide, and chloroform gave a mixture of cis- and trans-3-azido-3-phenylbicyclo[3.1.0]hexanes.
Iodoform
Definition:
(n.) A yellow, crystalline, volatile substance, CI3H, having an offensive odor and sweetish taste, and analogous to chloroform. It is used in medicine as a healing and antiseptic dressing for wounds and sores.
Example Sentences:
(1) Meanwhile, higher dose of iodoform was required for induction of aplasia or depression of the dental pulp or root dentain.
(2) The toxicity of iodoform is probably unrecognized if the rarity of the observations published and the amount of iodoform gauzes annually sold are compared.
(3) The iodoform paste that was applied as a result of canal treatment, which was performed on the left mandibular second premolar, did not only overfill the apical lesion of that tooth but also extended as far as the apical region of the left mandibular second molar.
(5) The root canal filling material "Vitapex" (Neo Dental Chemical Products Co., Tokyo), made of calcium hydroxide and iodoform with the addition of silicone oil, was experimentally injected into the mandibular canals of dogs, and its effect on the alveolar nerve tissue was examined by light and electron microscopy.
(6) Postoperative treatment with a vaselinated iodoform gauze lasted between 3 and 5 weeks.
(7) Plasma iodine determinations were carried out on the toxic patient and three others with iodoform containing packs.
(8) One hundred and forty eight patients with bilateral symmetrically impacted lower third molars entered a clinical crossover trial to compare the effects on postoperative recovery of a Bismuth Iodoform Paraffin Paste (BIPP) socket dressing, primary closure using a resorbable suture (Softgut) and to ascertain if prophylactic metronidazole influenced the outcome.
(9) The disinfection treatment carried out on these same surfaces had a positive effect, leading to a reduction in microbial findings of at least 98% both using energetic disinfectants based on iodoform products, and also milder disinfectants based on quaternary ammonium.
(10) The metabolism of haloforms to CO followed the halide order; thus, iodoform yielded the greatest amount of CO, whereas chloroform yielded the smallest amount.
(11) Three cases of iodoform poisoning are described following dressings with 10% iodoform gauze (0.10 x 5 m) on extended wounds.
(12) It was concluded that the Ca(OH)2-iodoform paste, Vitapex, produced better results than Ca(OH)2-CMCP paste in treatment of infected nonvital permanent teeth with incompletely formed apices.
(13) Immediate wound care involved dressing the defect with zinc iodoform paste on ribbon gauze for 4 weeks when complete granulation and epithelialisation occurred.
(14) The closest to the ideal appears to be a calcium hydroxide-iodoform mixture.
(15) Tested was the effect of the iodoform preparation iosan and the quaternary ammonium preparation bradofen against the viruses of the Newcastle disease (strain La Sota), laryngotracheitis (strain TsNIIP) and fowl pox (strain FK) in birds.
(16) A paste consisting of equal amounts of calcium hydroxide and iodoform mixed with glycerin was used.
(17) The surgical procedure is a modification of the maxillary sinus approach, which includes the use of iodoform gauze packing, nasal antrostomy, a double layer oral closure and prophylactic antibiotics.
(18) 40 teeth of a complex canal anatomy and or in the posterior position in the buccal cavity were submitted to either a manual canalisation preparation or endosconic followed by monconic canal filling with a paste: 3 inc oxyde eugenol and iodoform.
(19) Seven substances (1,2-dibromo-3-chloropropane, 1,2-dibromoethane, 1,2-dichloroethane, vinyl bromide, hexachloro-1,3-butadiene, iodoform and vinilydene chloride) were mutagenic at non-lethal doses.
(20) The ultrastructural aspects of initial calcification in the rat subcutaneous tissues elicited by the root canal filling material Vitapex, made up of calcium hydroxide and iodoform with the addition of silicone oil, were studied by means of electron microscopic and cytochemical techniques.