(1) DHCA furthermore reduced the secretion of exogenous cholic acid when co-infused with DHCA.
(2) However, plasma disappearance if intravenously injected glycine conjugate of cholic acid was significantly delayed in all subjects, suggesting that this is a more sensitive test of hepatic excretory function and may be of value for assessing hepatic function in patients with this rare genetic disorder.
(3) Allo-deoxycholic acid was formed only in cell extracts prepared from bacteria induced by cholic acid, suggesting that their formation may be a branch of the cholic acid 7 alpha-dehydroxylation pathway in this bacterium.
(4) The two primary bile acids, cholic acid and chenodeoxycholic acid, and their metabolic products, deoxycholic acid, lithocholic acid, and ursodeoxycholic acid, were present in all bile samples and constituted greater than 97% of all bile acids.
(5) The percentage of the bile acid pool represented by chenodeoxycholic acid was significantly higher, and that cholic acid correspondingly lower on the gallstone-inducing diet.
(6) Intravenous administration of cholic acid in vivo elicits a dose-dependent negative chronotropic effect.
(7) Urine from patients with cerebrotendinous xanthomatosis (CTX) was found to contain a number of minor bile acids along with three major bile acids, 7-epicholic acid, norcholic acid, and cholic acid.
(8) Cholic acid kinetics in 3 patients showed decreased synthesis rates and pool sizes with both drugs.
(9) The time course of the blood and bile lipids and the relationship thereof reflect the depression of cholesterol hydroxylation processes and reduction with age of cholic and deoxycholic acids synthesis and conjugation intensities in the patients with cholelithiasis, as well as a reduction of deoxycholic acid synthesis in normal subjects.
(10) To test this possibility, we have attempted to localize ursodeoxycholic acid in hepatocytes and portal bile duct cells by an indirect immunoperoxidase technique using specific polyclonal antibodies against ursodeoxycholic acid and cholic acid conjugates.
(11) For various reasons the use of cholic acid is especially recommended.
(12) Preparations of liver from two patients with Zellweger syndrome had no capacity to catalyze conversion of THCA into cholic acid.
(13) The bile acid excretion with a 1:3 bypass was 49% of that with a 3:1 bypass (P less than 0.01), with a slight predominance of chenodeoxycholic over cholic acid in 1:3 compared with 3:1 bypass.
(14) Determination of the initial plasma disappearance rate of 14C-cholic acid injected intravenously and its transformation to 14C-cholic acid injected intravenously and its transformation to 14C-deoxycholic acid may help to classify patients with cirrhosis of the liver.
(15) The diagnostic value of 14C-cholic acid plasma clearance following oral administration was evaluated.
(16) Serum levels of 7 alpha-hydroxycholesterol, 7 beta-hydroxycholesterol and 26-hydroxycholesterol were determined in several groups of patients: normals, untreated patients suffering from cerebrotendinous xanthomatosis, patients suffering from cerebrotendinous xanthomatosis and treated with either chenodeoxycholic acid or cholic acid in an effective dose, patients suffering from cerebro-hepato-renal syndrome, patients suffering from hypercholesterolemia and treated with cholestyramine for prolonged periods and one patient presumed to be suffering from an inborn error of metabolism in bile acid synthesis.
(17) When the old group of mice was fed with a diet containing vitamin E for two months, the excretion of bile acid-14C derived from injected cholesterol4-14C or cholic acid-24-14C was increased and the disappearance of hepatic cholesterol-14C became more rapid.
(18) This was examined by mass spectrometry using direct inlet technique, but no free cholic acid could be identified.
(19) The effects of prolonged intravenous infusions of cholic acid into fetal lambs are described in this study.
(20) Bacterial modification of norcholic acid was similar to but less extensive than that of cholic acid.
Colic
Definition:
(n.) A severe paroxysmal pain in the abdomen, due to spasm, obstruction, or distention of some one of the hollow viscera.
(a.) Of or pertaining to colic; affecting the bowels.
(a.) Of or pertaining to the colon; as, the colic arteries.
Example Sentences:
(1) Five horses raced successfully and lowered the lifetime race records, 1 horse was sound and trained successfully, but died of colic, and 1 horse was not lame in early training.
(2) At operation the superior mesenteric artery was found to be occluded distal to the origin of the middle colic artery.
(3) However, when hypoxia occurred during colic surgery in the last 60 days of pregnancy, the mares either aborted or delivered severely compromised foals that did not survive.
(4) Traumatic hemobilia is commonly associated with cavitary injuries to the liver, and is classically characterized by a triad of findings: GI bleeding, biliary colic, and jaundice.
(5) Twelve patients with biliary colic had no evidence of gallstones but underwent cholecystokinin-augmented hepatobiliary scintigraphy that revealed gallbladder ejection fractions of less than 35%.
(6) These data were compared with the angiogram of the right superior colic artery supplying the graft, systematically performed on the fifteenth postoperative day, and with the clinical course of follow-up for 3 months.
(7) Of 18 of these cases with available histories, 6 subsequently had one or more episodes of colic since surgery of which 5 eventually died or were euthanased due to further colic; the remaining 12 have remained free from recurrence of colic for longer than 6 months.
(8) A 10-year-old Appaloosa stallion was referred for evaluation of colic.
(9) to treat a colic or to accelerate the spontaneous discharge of stones, seems to be only rarely possible: Glucagone shows a markable decrease of ureteral peristalsis in animal experiments.
(10) A computer-based search was conducted of medical and necropsy records of horses admitted to the teaching hospital from Jan 1, 1979, to Dec 31, 1987, to obtain the records of all horses admitted to the hospital for colic and subsequently found to have gastric rupture.
(11) The results of the clinical use of Bencyclane in cases of ureteric colic are described and discussed.
(12) Those patients in whom repeatedly renal stones had been evident at the time of the operation, reported increased colics with partly spontaneous discharge of stones shortly after the operation; the i.v.p.
(13) Episodes of recurrent macroscopic hematuria also occur, but the pain cannot be attributed to colic due to blood clots in the ureter.
(14) If IH is symptomatic, the symptoms are hematuria, renal colic, or obstructive uropathy with or without infection.
(15) We consider US to be a valuable method in patients with previous contrast media reactions, but recommend urography as the standard imaging method when renal colic is clinically suspected.
(16) The colic graft was anastomosed to the hypopharynx in 43 cases, to the oropharynx in 14 cases, and in 33 cases a pharyngoplasty was done.
(17) Strong associations between exposure to lead and the prevalence of central nervous system symptoms, abdominal colic, and constipation were recorded.
(18) Hemostatic profiles were determined in 30 horses with clinical colic.
(19) Ten successive patients with acute ureteric colic were given 1 mg of glucagon and two litres of fluid administered by the intravenous route and analgesia as required over three hours.
(20) Gastro-colic fistula is a rare complication of benign peptic ulcer disease.