What's the difference between chromosome and deletion?

Chromosome


Definition:

  • (n.) One of the minute bodies into which the chromatin of the nucleus is resolved during mitotic cell division; the idant of Weismann.

Example Sentences:

  • (1) In contrast, DNA polymerase alpha, the enzyme involved in chromosomal DNA replication, was relatively insensitive to CA1.
  • (2) Here we report that sperm from psr males fertilizes eggs, but that the paternal chromosomes are subsequently condensed into a chromatin mass before the first mitotic division of the egg and do not participate in further divisions.
  • (3) Clonal abnormalities involving chromosomes 3 and 21 were noted in two patients.
  • (4) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
  • (5) The constitution of chromosomes in the two plasmacytomas remained remarkably stable in their homogeneous modal population.
  • (6) The data on mapping the episomal plasmid integration sites in yeast chromosomes I, III, IV, V, VII, XV are presented.
  • (7) The purpose of these studies was to better understand the molecular basis of chromosome aberration formation after mitomycin C treatment.
  • (8) Twelve families with Wiskott-Aldrich syndrome (WAS) were studied by linkage analysis using 10 polymorphic marker loci from the X-chromosome pericentromeric region.
  • (9) The effects of phenoxyacetic acid herbicides were investigated on the induction of chromosome aberrations in human peripheral lymphocyte cultures in vitro and in lymphocytes of exposed workers in vivo.
  • (10) Pituitary weight, mitotic index and chromosomes were studied in male rats following a single or repeated dose of estradiol-benzoate for a total period of 210 days.
  • (11) Alleles in this region can be exchanged between X and Y chromosomes and are therefore inherited as if autosomal.
  • (12) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
  • (13) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.
  • (14) The induction of cells with two Y chromosomes by nitrogen mustard (NM) was examined.
  • (15) Several investigators have attempted to correlate chromosomal abnormalities with Cornelia de Lange Syndrome (CLS), but none of them have been conclusive.
  • (16) The technique resolved chromosomes in the size range of 100 kb-1 Mb.
  • (17) A number of recurring chromosomal abnormalities have been identified in childhood acute lymphoblastic leukemia.
  • (18) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
  • (19) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
  • (20) The numerical chromosome values in 53 human tumors were determined and compared with the modal DNA values as measured by flow cytometry.

Deletion


Definition:

  • (n.) Act of deleting, blotting out, or erasing; destruction.

Example Sentences:

  • (1) Moreover, homozygous deletion of the FMS gene may be an important event in the genesis of the MDS variant 5q- syndrome.
  • (2) None of the 4NQO- or 4HAQO-induced mutants is a multilocus deletion mutant.
  • (3) In strains completely deleted for galR, the gene which encodes the Gal repressor, the operon is derepressed by only 10-fold without an inducer.
  • (4) Delta roc, which extends from base pairs 41883 to 43825, overlaps the nin5 deletion, which extend from base pairs 40501 to 43306.
  • (5) The deletions and substitutions appear to occur in separate molecules.
  • (6) By external deletion, we have identified RXE composed of 205 nucleotides.
  • (7) A 6.4 kilobase C4B-5'-specific Taq I fragment usually provided a reliable guide to the presence of a C4A deletion but unusually in one instance this fragment was found to be a marker of a functioning C4A gene.
  • (8) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
  • (9) Analysis of glutamate dehydrogenase (GDH) expression by enzyme assay and immunoblots, as well as Northern and dot blots of poly (A)+ RNA, in the deletion strains indicates that there are two upstream regulatory sequences that control the level of gene expression.
  • (10) Analysis of genetic markers associated with the deleted haplotypes pointed to the independent origin of similar deletions and the involvement of intergenic sequences in the mispairing-recombination process.
  • (11) Cells transfected with either the first or second construct and selected for the TK+ phenotype were then tested for TK induction after superinfection with HSV-1(F) delta 305, containing a deletion in the coding sequences of the TK gene, and viruses containing, in addition, a ts lesion in the alpha 4 regulatory protein (ts502 delta 305) or in the beta 8 major DNA-binding protein (tsHA1 delta 305).
  • (12) No 7 beta-hydroxysteroid dehydrogenase activity and only a trace of 7 alpha-hydroxysteroid dehydrogenase activity could be demonstrated when bile acid was deleted from the growth medium.
  • (13) All four human MBP variants were identical except for the insertion of deletion of two peptide fragments corresponding to those encoded by exons 2 and 5 of the MBP gene.
  • (14) Molecular analysis of HPRT- mutant DNAs showed a high frequency (69%) of clones with partial or full deletions of the hprt gene among radiation-induced mutants compared with spontaneous mutants (31%).
  • (15) Reciprocal translocations involving the short arm of acrocentric chromosomes can segregate to produce partial duplications without associated deletions.
  • (16) Considering those portions of the molecule that can be deleted without a loss of catalytic activity, one is left with a catalytic center of approximately 130 nucleotides that is solely responsible for the molecule's activity.
  • (17) Twenty-nine deletion breakpoints were mapped in 220 kb of the DXS164 locus relative to potential exons of the Duchenne and Becker muscular dystrophy gene.
  • (18) Then these two repeats were separated and deleted systematically to obtain various deletions.
  • (19) Although T cell tolerance to self antigens is primarily a reflection of clonal deletion in the thymus, recent evidence suggests that mature T cells are subject to negative regulation in the post-thymic environment: Extrathymic tolerance is the result of clonal anergy in some studies and T cell deletion in others.
  • (20) We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13.