What's the difference between chromosome and transvection?

Chromosome


Definition:

  • (n.) One of the minute bodies into which the chromatin of the nucleus is resolved during mitotic cell division; the idant of Weismann.

Example Sentences:

  • (1) In contrast, DNA polymerase alpha, the enzyme involved in chromosomal DNA replication, was relatively insensitive to CA1.
  • (2) Here we report that sperm from psr males fertilizes eggs, but that the paternal chromosomes are subsequently condensed into a chromatin mass before the first mitotic division of the egg and do not participate in further divisions.
  • (3) Clonal abnormalities involving chromosomes 3 and 21 were noted in two patients.
  • (4) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
  • (5) The constitution of chromosomes in the two plasmacytomas remained remarkably stable in their homogeneous modal population.
  • (6) The data on mapping the episomal plasmid integration sites in yeast chromosomes I, III, IV, V, VII, XV are presented.
  • (7) The purpose of these studies was to better understand the molecular basis of chromosome aberration formation after mitomycin C treatment.
  • (8) Twelve families with Wiskott-Aldrich syndrome (WAS) were studied by linkage analysis using 10 polymorphic marker loci from the X-chromosome pericentromeric region.
  • (9) The effects of phenoxyacetic acid herbicides were investigated on the induction of chromosome aberrations in human peripheral lymphocyte cultures in vitro and in lymphocytes of exposed workers in vivo.
  • (10) Pituitary weight, mitotic index and chromosomes were studied in male rats following a single or repeated dose of estradiol-benzoate for a total period of 210 days.
  • (11) Alleles in this region can be exchanged between X and Y chromosomes and are therefore inherited as if autosomal.
  • (12) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
  • (13) In the triploids, the 40 female chromosomes present (mouse, n = 20) were derived from a single diploid pronucleus formed after the extrusion of a first polar body, and following the monospermic fertilization of primary oocytes.
  • (14) The induction of cells with two Y chromosomes by nitrogen mustard (NM) was examined.
  • (15) Several investigators have attempted to correlate chromosomal abnormalities with Cornelia de Lange Syndrome (CLS), but none of them have been conclusive.
  • (16) The technique resolved chromosomes in the size range of 100 kb-1 Mb.
  • (17) A number of recurring chromosomal abnormalities have been identified in childhood acute lymphoblastic leukemia.
  • (18) Since the plasmid-cured strains did not contain DNA sequences homologous to plasmid DNA, the gene for the free-inclusion protein must be encoded in the chromosome.
  • (19) The gene, which is located at chromosome XIII, is transcribed as a mRNA of about 2.7 kilobases, and the amount of message has been found to increase 3- to 4-fold during the culture.
  • (20) The numerical chromosome values in 53 human tumors were determined and compared with the modal DNA values as measured by flow cytometry.

Transvection


Definition:

  • (n.) The act of conveying or carrying over.

Example Sentences:

  • (1) Chromosomal rearrangements which disrupt transvection possess a breakpoint in a particular segment of the chromosome arm bearing the transvection-sensitive gene (arm 2L for the DDP-C and 3R for the BX-C); this segment of each arm has been termed the critical region by Lewis (1954).
  • (2) The zeste gene product is required for transvection effects that imply the ability of regulatory elements on one chromosome to affect the expression of the homologous gene in a somatically paired chromosome.
  • (3) The factor Dichaete (D3) permits easier scoring of the transvection phenotype.
  • (4) Possible mechanisms for the trans-acting effect of niv-525 and its relationship to other examples of allelic interactions, such as transvection in Drosophila melanogaster, are discussed.
  • (5) These results indicate that both the zeste-white interaction and transvection effects require the formation of high order aggregates.
  • (6) We discuss the normal cis regulatory role of these functions involved in trans interactions between homologous Ubx genes, as well as the implications of our results for the current models on transvection.
  • (7) Only Cbx2 and CbxIRM (a revertant of Cbx1) show synapsis-dependent gene expression ("transvection").
  • (8) These recent observations continue a history of studies concerning zeste and transvection which has inspired molecular models linking chromosome structure and positioning to the modulation of gene expression.
  • (9) Somatic transfer of genomic imprinting between homologs by means of a transvection-like process between paired Tme and T loci is proposed as a model to explain the results obtained.
  • (10) We show that this domain is responsible for the extensive aggregation properties of zeste that are required for its role in transvection phenomena.
  • (11) A new adaptation of the bithorax transvection method by Mendelson permits the recovery of high yields of chromosome aberrations in a fast one-generation test.
  • (12) We have confirmed that, although the Ubx1 allele does not produce detectable Ubx proteins (UBX), it does retain other genetic functions detectable by their effects on the expression of a paired, homologous Ubx allele, i.e., by transvection.
  • (13) The conditions necessary for each transvection effect were determined from these transvection groups.
  • (14) The genetic properties of the proximity-dependent allelic complementation (termed transvection effects) at the BX-C and DPP-C, are quite similar.
  • (15) Transvection was explained by trans-activation of promoter in y2-allele by enhancer of y1-allele.
  • (16) The bithorax34e mutation only transvects with Ultrabithorax mutations with a contiguous Ultrabithorax transcriptional unit.
  • (17) The zeste gene product is involved in two types of genetic effects dependent on chromosome pairing: transvection and the zeste-white interaction.
  • (18) Special attention is paid to the transvection effect (synapsis-dependent interaction between white and zeste genes), cis-acting regulatory elements and the behaviour of the white genes introduced into the genome by P element-mediated DNA transformation.
  • (19) Surprisingly, previous genetic experiments indicate that zeste is a nonessential gene shown only to act in a dispensable regulatory process termed transvection.
  • (20) One can discriminate between otherwise phenotypically similar mutations via their transvection behavior.

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