(a.) Continuing for a long time; lingering; habitual.
Example Sentences:
(1) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(2) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(3) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(4) Experience of pain is modified by intern and extern influences, and it can appear very multiformly in the chronicity.
(5) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(6) Patients were chronically ill homosexual men with multiple systemic opportunistic infections.
(7) The present study examined whether the lack of chronic hemodynamic effects of ANP in control rats was due to changes in vascular reactivity to the peptide.
(8) Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis.
(9) A chronic cannulation procedure is described which allows for sampling vomeronasal organ (VNO) contents repeatedly in freely moving conscious subjects.
(10) During the chronic phase, pain was assessed using visual analogue scales at 8 AM and 4 PM daily.
(11) These data indicate that CSF levels are not inversely related to the blood neutrophil count in chronic idiopathic neutropenia and suggest that CSF is not a hormone regulating the blood neutrophil count in a manner analogous to the erythropoietin regulation of circulating erythrocyte levels.
(12) Erythrocyte membrane choline transport is abnormally high in chronic renal failure.
(13) 1 The effects of chronic ethanol intake on the elimination kinetics of antipyrine were determined in nineteen male alcoholic subjects with comparison made to fourteen male volunteers.
(14) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(15) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(16) Alcohol abuse remains the predominant cause of chronic liver disease in the Western world.
(17) These results show that lipo-PGI2 at a very low dose would be beneficial as a treatment for relieving the clinical symptoms of chronic cerebral infarction and that lipid microspheres are a useful drug carrier for PGI2 analogue therapy.
(18) Anxious mood and other symptoms of anxiety were commonly seen in patients with chronic low back pain.
(19) Asthma is probably the commonest chronic disease in the United Kingdom, and its attendant morbidity extends outside the possible scope of the hospital sector.
(20) We recommend analysing the urine for porphyrins in HIV-positive patients who have chronic photosensitivity of the skin.
Elephantiasis
Definition:
(n.) A disease of the skin, in which it become enormously thickened, and is rough, hard, and fissured, like an elephant's hide.
Example Sentences:
(1) Choroido-retinal degeneration, genital elephantiasis and hydrocoele, commonly associated with onchocerciasis in other parts of the Sudan, are absent.
(2) From 1960 to date, there have been four cases of elephantiasis penis in the urologic clinic of the Katharinenhospital in Stuttgart, which were operated on by skin transplantation.
(3) All of Goyrand's work was edited by Masson in 1870, including a superb case report of giant elephantiasis of the penis and scrotum, a study on cleft lip and the technique of using collodion bands to close large wounds [corrected].
(4) The author developed a microlymphatico-venous procedure to treat elephantiasis of the scrotum and applied it clinically with good results.
(5) Only two cases of leg elephantiasis and one breast elephantiasis were found.
(6) Larvae are responsible for damage to various structures of the lymphatic system (thrombo-lymphangitis, acute or granulomatous lymphadenitis...) into which they migrate, explaining the mechanism of elephantiasis.
(7) Clinical signs of disease with the exception of elephantiasis, showed good correlations with Mf-rates but not with MfD50 values.
(8) Sera from 50 patients with several clinical forms of the disease including asymptomatic carriers, tropical pulmonary eosinophilia, elephantiasis, filarial fever and chyluria were analysed.
(9) In the irreversible lymphoedema (stage III) and in the elephantiasis (stage IV) the following operations have been developed: ligature of ectatic lymphtrunks, peripheral lymphovenous and lymphadenovenous shunts, skin-flap transplantations, free or pediculated transplantation of the greater omentum, lymphangioplastic operations (Thompson-operation) or excisional operations (Servelle-operation).
(10) Patients with elephantiasis seldom have circulating microfilariae in their blood.
(11) Thus, the ability to initiate the formation of obstructive lesions in the dilated lymphatics of chronically parasitized nude mice by immunological reconstitution, suggests that several complex mechanisms might operate in stages to cause filarial elephantiasis.
(12) An estimated 2500 to 40000 men suffering from hydroceles and 3700 to 40000 elephantiasis patients demonstrate that bancroftian filariasis has to be regarded a health problem in rural coastal Liberia.
(13) In Kakap 18% of 226 persons examined had a clinical history of filariasis and elephantiasis was seen in 13%.
(14) Analysis of the microfilarial densities at different ages and the number of anatomical sites showing lymph gland enlargement or elephantiasis have been used to provide evidence on the clustering of infections and pathogenesis.Although there is no evidence of clustering of risk of infection, there is evidence favouring the clustering of adult filariae in individuals.
(15) The diagnosis of elephantiasis nostras can often be made based on the clinical findings, but examination of tissue may be helpful to rule out associated conditions, especially malignancies.
(16) Lymphatic filariasis is expressed clinically as elephantiasis.
(17) In spite of a regular intravenous protein substitution for many years, this patient had developed a monstrous elephantiasis of the lower extremities.
(18) An elderly man had elephantiasis of a lower extremity that was partially covered with verrucose papules, but also had sharply delineated islands of normal-appearing skin.
(19) Whereas clinical descriptions of grotesque lymphedema and standard light microscopy in human filariasis have elucidated the natural progression of this disease, the link between the nematode and vascular abnormalities including elephantiasis remains poorly understood.
(20) A case of elephantiasis nostras in a lower limb is presented.