(a.) Continuing for a long time; lingering; habitual.
Example Sentences:
(1) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
(2) We conclude that chronic emphysema produced in dogs by aerosol administration of papain results in elevated pulmonary artery pressure, which is characterized pathologically by medial hypertrophy of small pulmonary arteries.
(3) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(4) Experience of pain is modified by intern and extern influences, and it can appear very multiformly in the chronicity.
(5) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
(6) Patients were chronically ill homosexual men with multiple systemic opportunistic infections.
(7) The present study examined whether the lack of chronic hemodynamic effects of ANP in control rats was due to changes in vascular reactivity to the peptide.
(8) Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis.
(9) A chronic cannulation procedure is described which allows for sampling vomeronasal organ (VNO) contents repeatedly in freely moving conscious subjects.
(10) During the chronic phase, pain was assessed using visual analogue scales at 8 AM and 4 PM daily.
(11) These data indicate that CSF levels are not inversely related to the blood neutrophil count in chronic idiopathic neutropenia and suggest that CSF is not a hormone regulating the blood neutrophil count in a manner analogous to the erythropoietin regulation of circulating erythrocyte levels.
(12) Erythrocyte membrane choline transport is abnormally high in chronic renal failure.
(13) 1 The effects of chronic ethanol intake on the elimination kinetics of antipyrine were determined in nineteen male alcoholic subjects with comparison made to fourteen male volunteers.
(14) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(15) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(16) Alcohol abuse remains the predominant cause of chronic liver disease in the Western world.
(17) These results show that lipo-PGI2 at a very low dose would be beneficial as a treatment for relieving the clinical symptoms of chronic cerebral infarction and that lipid microspheres are a useful drug carrier for PGI2 analogue therapy.
(18) Anxious mood and other symptoms of anxiety were commonly seen in patients with chronic low back pain.
(19) Asthma is probably the commonest chronic disease in the United Kingdom, and its attendant morbidity extends outside the possible scope of the hospital sector.
(20) We recommend analysing the urine for porphyrins in HIV-positive patients who have chronic photosensitivity of the skin.
Serious
Definition:
(a.) Grave in manner or disposition; earnest; thoughtful; solemn; not light, gay, or volatile.
(a.) Really intending what is said; being in earnest; not jesting or deceiving.
(a.) Important; weighty; not trifling; grave.
(a.) Hence, giving rise to apprehension; attended with danger; as, a serious injury.
Example Sentences:
(1) This should not be a serious limitation to the application of the RIA in the detection of venous thrombosis.
(2) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(3) "There is a serious risk that a deal will be agreed between rich countries and tax havens that would leave poor countries out in the cold.
(4) Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient.
(5) No report can be taken seriously if its authors weren’t even in Yemen to conduct investigations.” The UN team was not given permission to enter the country.
(6) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(7) Vancomycin is the antibiotic of choice for serious MRSA infections; PRPs and cephalosporins generally are not effective.
(8) An age- and education-matched group of women with no family history of FXS was asked to predict the seriousness of problems they might encounter were they to bear a child with a handicapping condition.
(9) The most serious complications following operative treatment are retained bile duct calculi (2.8%), wound infection and biliary fistulae.
(10) Guardian Australia reported last week that morale at the national laboratory had fallen dramatically, with one in three staff “seriously considering” leaving their jobs in the wake of the cuts.
(11) In case of biliary and pancreatic duct obstruction with pure pancreatic reflux, both oedema and inflammatory infiltrations were evident, whereas, in the presence of biliary reflux too, more serious histological features were detected.
(12) Autopsy revealed serious somatic diseases (stenosis of the ileum in two cases and brain tumor in one); their symptoms had been largely overlapped by those of anorexia nervosa.
(13) The above treatment is tolerated well and no serious side effects have been observed.
(14) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(15) Earlier recognition of foul-smelling mucoid discharge on the IUD tail, or abnormal bleeding, or both, as a sign of early pelvic infection, followed by removal of the IUD and institution of appropriate antibiotic therapy, might prevent the more serious sequelae of pelvic inflammation.
(16) Left ventricular rupture is a serious complication of mitral valve replacement.
(17) Other serious complications were reservoir perforation during catheterisation in 3 and development of stones in the reservoir in 2 patients.
(18) For application to mammalian cells, however, two serious problems require resolution: (1), correction of TPP+ binding to intracellular constituents and (2), estimation of the considerable TPP+ accumulation in mitochondria.
(19) At least 1 episode of serious infection occurred in 34 of the 60 adult patients and 25 of the 30 children.
(20) These high Danish rates seem to reflect the true prevalence and incidence in the less serious types of progressive muscular dystrophy, probably because the Danish health system with free medical care and easy access to specialized hospital departments makes it possible to identify all cases of progressive muscular dystrophy.