What's the difference between cinchonism and human?
Cinchonism
Definition:
(n.) A condition produced by the excessive or long-continued use of quinine, and marked by deafness, roaring in the ears, vertigo, etc.
Example Sentences:
(1) In all patients plasma quinine concentrations exceeded the high minimum inhibitory concentration for Plasmodium falciparum malaria prevalent in Thailand within four hours of the start of treatment but did not cause toxicity other than mild cinchonism.
(2) Cinchonism is the well-known syndrome of quinine overdose involving disturbances of vision, hearing, and balance, which has occasional importance in aviation pathology, usually related to ingestion of tonic water.
(3) Cinchonism occurred in 25% of those treated with quinine, but it was fully reversible and never necessitated withdrawal of the drug.
(4) However, the simple expedient of increasing the nightly dose of quinine may carry the concomitant risk of cinchonism.
(5) They also experienced the classic symptoms of cinchonism, including nausea, vomiting, and tinnitus.
(6) Several features are common to both an acute single overdose in self-poisoning and accumulation of quinine during therapy for malaria: together they are termed cinchonism.
(7) ; one developed cinchonism and one malaise, the remainder showing no excess toxicity compared with epirubicin alone.
(8) These reactions include GI intolerance, cardiac arrhythmias, fever with and without associated hepatic dysfunction or leukopenia, cinchonism, and hemolytic anemia.
(9) Signs of cinchonism and common ototoxins are discussed.
(10) Quinine intoxication can also cause cinchonism, which is marked by tinnitus, vertigo, blurred vision and scotomata, and possible optic atrophy or death.
(11) We conclude that quinine is highly effective in the treatment of P. falciparum infection and is mandatory if the clinical condition requires a fast-acting blood schizonticide, in cases of hyper-parasitaemia and if multi-drug resistance occurs; its use should not be restricted by reversible side-effects such as cinchonism.
Human
Definition:
(a.) Belonging to man or mankind; having the qualities or attributes of a man; of or pertaining to man or to the race of man; as, a human voice; human shape; human nature; human sacrifices.
(n.) A human being.
Example Sentences:
(1) The absolute recoveries of diazepam, nordazepam and flurazepam in human milk were 84, 86 and 92% and in human plasma 97, 89 and 94%, respectively.
(2) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(3) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(4) The distribution and configuration of the experimental ruptures were similar to those usually noted as complications of human myocardial infarction.
(5) By electrophoresis and scanning densitometry, actin was found to constitute about 4% to 6% of the total cellular protein in the human corneal epithelium.
(6) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(7) Assessment of the likelihood of replication in humans has included in vitro exposure of human cells to the potential pesticidal agent.
(8) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(9) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
(10) Phospholipid methylation in human EGMs is distinctly different from that in rat EGMs (Hirata and Axelrod 1980) in that the human activity is not Mg++-dependent, and apparent methyltransferase I activity is located in the external membrane surface.
(11) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(12) On the other hand, human IL-9, which is a homologue to murine P40, was cloned from a cDNA library prepared with mRNA isolated from PHA-induced T-cell line (C5MJ2).
(13) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
(14) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(15) Detergent-solubilized HLA antigens were isolated from a human lymphoblastoid cell using an anti-beta2-microglobulin immunoaffinity column.
(16) We postulate that FAA may affect the human peripheral and mucosal immune system.
(17) The human placental villus tissue contains opioid receptors and peptides.
(18) The origins of aging of higher forms of life, particularly humans, is presented as the consequence of an evolved balance between 4 specific kinds of dysfunction-producing events and 4 kinds of evolved counteracting effects in long-lived forms.
(19) The result has been called the biggest human upheaval since the Second World War.
(20) It was the purpose of the present study to describe the normal pattern of the growth sites of the nasal septum according to age and sex by histological and microradiographical examination of human autopsy material.