What's the difference between clearance and passage?

Clearance


Definition:

  • (n.) The act of clearing; as, to make a thorough clearance.
  • (n.) A certificate that a ship or vessel has been cleared at the customhouse; permission to sail.
  • (n.) Clear or net profit.
  • (n.) The distance by which one object clears another, as the distance between the piston and cylinder head at the end of a stroke in a steam engine, or the least distance between the point of a cogwheel tooth and the bottom of a space between teeth of a wheel with which it engages.

Example Sentences:

  • (1) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (2) Work on humoral responses has focused on lysozyme, the hemagglutinins (especially in the oyster), and the clearance of certain antigens.
  • (3) It is suggested that the rapid phase is due to clearance of peptides in the circulation which results in a fall to lower blood concentrations which are sustained by slow release of peptide from binding sites which act as a depot.
  • (4) In addition to esophageal manometry, we also performed acid-clearance studies and examined salivary output, acid-neutralizing capacity, and bicarbonate concentration.
  • (5) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
  • (6) Pharmacokinetic parameters, such as these clearances, had large intersubject variations.
  • (7) Mortality, blood clearance and organ distribution of 125I labelled Escherichia coli were determined.
  • (8) Unbound fractions was significantly correlated with serum albumin concentration (r = -0.344, p less than 0.046) and renal clearance (r = 0.394, p less than 0.021) but not with total body clearance or volume of distribution.
  • (9) Renal blood flow was measured in all patients by Hippuran-clearance and xenon-washout.
  • (10) Temelastine produces these species-specific changes by enhancing thyroxine clearance from the circulation in the rat, but not in the dog or mouse.
  • (11) Our study suggests that a major part of the renal antimineralocorticoid activity of spironolactone may be attributable to minor sulfur-containing metabolites or their precursors having a high renal clearance that affords access to their site of activity via the renal tubular fluid.
  • (12) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
  • (13) These results suggest that glomerular IgA are IgA polymers and decreased hepatic clearance of hepatic IgA polymers may be responsible for the glomerular deposition of IgA.
  • (14) Furthermore, the changes in both interstitial fluid and testicular venous blood levels of testosterone do not always parallel those in peripheral venous blood, suggesting that changes in testicular blood flow and peripheral clearance rates of testosterone may also be important in the control of circulating testosterone concentrations.
  • (15) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
  • (16) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
  • (17) [14C]Sucrose biliary clearance increased in treated animals, suggesting an increased permeability of the biliary system to sucrose.
  • (18) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
  • (19) The time to recovery of full consciousness, time to parasite clearance, and mortality were examined with Cox proportional-hazards regression analysis.
  • (20) Tracheal mucus transport rate (TMTR) and quantitative clearance of aerosolized Escherichia coli from the trachea, lung, and air sac were measured in healthy unanesthetized turkeys and in turkeys exposed by aerosol to a La Sota vaccine strain of Newcastle disease virus (NDV).

Passage


Definition:

  • (v. i.) The act of passing; transit from one place to another; movement from point to point; a going by, over, across, or through; as, the passage of a man or a carriage; the passage of a ship or a bird; the passage of light; the passage of fluids through the pores or channels of the body.
  • (v. i.) Transit by means of conveyance; journey, as by water, carriage, car, or the like; travel; right, liberty, or means, of passing; conveyance.
  • (v. i.) Price paid for the liberty to pass; fare; as, to pay one's passage.
  • (v. i.) Removal from life; decease; departure; death.
  • (v. i.) Way; road; path; channel or course through or by which one passes; way of exit or entrance; way of access or transit. Hence, a common avenue to various apartments in a building; a hall; a corridor.
  • (v. i.) A continuous course, process, or progress; a connected or continuous series; as, the passage of time.
  • (v. i.) A separate part of a course, process, or series; an occurrence; an incident; an act or deed.
  • (v. i.) A particular portion constituting a part of something continuous; esp., a portion of a book, speech, or musical composition; a paragraph; a clause.
  • (v. i.) Reception; currency.
  • (v. i.) A pass or en encounter; as, a passage at arms.
  • (v. i.) A movement or an evacuation of the bowels.
  • (v. i.) In parliamentary proceedings: (a) The course of a proposition (bill, resolution, etc.) through the several stages of consideration and action; as, during its passage through Congress the bill was amended in both Houses. (b) The advancement of a bill or other proposition from one stage to another by an affirmative vote; esp., the final affirmative action of the body upon a proposition; hence, adoption; enactment; as, the passage of the bill to its third reading was delayed.

Example Sentences:

  • (1) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
  • (2) Exposure to nanomolar concentrations of saralasin, an Ang II agonist, attenuated the passage of the fluorophores across the monolayers by 50-75%.
  • (3) Cultured cells from fourth to ninth passage showed positive labelling for S 100 protein, carbonic anydrase (CAA), glutamine synthetase (GS), alpha cristallin (alpha C) and polyclonal glial fibrillary acidic protein (GFAP) antibody, but were negative for both monoclonal GFAP antibody and also for Muller cells in the retina.
  • (4) In the case of the latter, it show either a more or less typical appearance of radicolography only or, more rarely, a picture which combines opacification of the epidural space with the subarachnoid passage of the contrast medium.
  • (5) After approximately 20 in vitro passages, Chinese hamster kidney (CHK) cell cultures transformed upon exposure to different strains of SV 40 can show a diploid modal chromosome number of 22 with chromosome counts exclusively or essentially in the diploid range (20-25).
  • (6) In late-passage and cloned HUT102 cells, an increase in HTLV production was concordant with a decrease in constitutive interferon production and the loss of mature T lymphocyte antigens.
  • (7) A reduction of salmonellae during the passage of the pump and pressure conduit-pipe, combining east- and west-side of Kiel fjord, could be seen.
  • (8) The resulting cell lines have a stable phenotype and retain the changes which result from transformation even after extended passaging.
  • (9) Abe’s longstanding efforts toward those goals, which include the successful passage of a state secrets act and efforts to expand the scope of Japan’s military activities have already damaged relations with China.
  • (10) It is inferred that in this experimental model (1) high-density lipoproteins are probably excreted in the glomerular filtrate, (2) alterations in the composition of the excreted lipoproteins may occur during their passage through the nephron.
  • (11) We report that kainic acid lesions of the posterior corpus striatum, which preferentially spare fibers of passage while destroying striatopallidal neurons, produce a stimulus-sensitive movement pattern in rats that has a highly specific sensory trigger.
  • (12) The cells have been maintained through 23 serial passages, and the modal number of chromosomes was calculated to be 55.
  • (13) The rate of passage of digesta was significantly reduced in both pair-fed control (50 per cent) and infected (74 per cent) groups.
  • (14) Unlike cells grown on plastic, RME cells grown on type I collagen were readily subculturable and serial subculture resulted in the cells undergoing 15-20 population doublings (5-6 passages) before exhibiting any loss of growth potential.
  • (15) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
  • (16) In addition, SPT16 is identical to CDC68, a gene previously shown to be required for passage through the cell cycle control point START.
  • (17) Selective catheterisation enabled opacification under pressure in more than 80 p. cent of cases, with perfect visualisation of the entire tubes and significant peritoneal passage.
  • (18) The effects of Urocalun and jumping exercise upon the passage of calculi were studied.
  • (19) The alterations in the glycosaminoglycans and collagen induced by hypoxia may cause changes in the passage of macromolecules through the aortic wall.
  • (20) Despite the lack of expression of the endogenous CYP17 gene in transfectants from late-passage cells, induced luciferase activity was higher in late-passage transfectants than early-passage transfectants for both the -2544 and -488 constructs.