What's the difference between clearance and reduction?

Clearance


Definition:

  • (n.) The act of clearing; as, to make a thorough clearance.
  • (n.) A certificate that a ship or vessel has been cleared at the customhouse; permission to sail.
  • (n.) Clear or net profit.
  • (n.) The distance by which one object clears another, as the distance between the piston and cylinder head at the end of a stroke in a steam engine, or the least distance between the point of a cogwheel tooth and the bottom of a space between teeth of a wheel with which it engages.

Example Sentences:

  • (1) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (2) Work on humoral responses has focused on lysozyme, the hemagglutinins (especially in the oyster), and the clearance of certain antigens.
  • (3) It is suggested that the rapid phase is due to clearance of peptides in the circulation which results in a fall to lower blood concentrations which are sustained by slow release of peptide from binding sites which act as a depot.
  • (4) In addition to esophageal manometry, we also performed acid-clearance studies and examined salivary output, acid-neutralizing capacity, and bicarbonate concentration.
  • (5) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
  • (6) Pharmacokinetic parameters, such as these clearances, had large intersubject variations.
  • (7) Mortality, blood clearance and organ distribution of 125I labelled Escherichia coli were determined.
  • (8) Unbound fractions was significantly correlated with serum albumin concentration (r = -0.344, p less than 0.046) and renal clearance (r = 0.394, p less than 0.021) but not with total body clearance or volume of distribution.
  • (9) Renal blood flow was measured in all patients by Hippuran-clearance and xenon-washout.
  • (10) Temelastine produces these species-specific changes by enhancing thyroxine clearance from the circulation in the rat, but not in the dog or mouse.
  • (11) Our study suggests that a major part of the renal antimineralocorticoid activity of spironolactone may be attributable to minor sulfur-containing metabolites or their precursors having a high renal clearance that affords access to their site of activity via the renal tubular fluid.
  • (12) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
  • (13) These results suggest that glomerular IgA are IgA polymers and decreased hepatic clearance of hepatic IgA polymers may be responsible for the glomerular deposition of IgA.
  • (14) Furthermore, the changes in both interstitial fluid and testicular venous blood levels of testosterone do not always parallel those in peripheral venous blood, suggesting that changes in testicular blood flow and peripheral clearance rates of testosterone may also be important in the control of circulating testosterone concentrations.
  • (15) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
  • (16) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
  • (17) [14C]Sucrose biliary clearance increased in treated animals, suggesting an increased permeability of the biliary system to sucrose.
  • (18) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
  • (19) The time to recovery of full consciousness, time to parasite clearance, and mortality were examined with Cox proportional-hazards regression analysis.
  • (20) Tracheal mucus transport rate (TMTR) and quantitative clearance of aerosolized Escherichia coli from the trachea, lung, and air sac were measured in healthy unanesthetized turkeys and in turkeys exposed by aerosol to a La Sota vaccine strain of Newcastle disease virus (NDV).

Reduction


Definition:

  • (n.) The act of reducing, or state of being reduced; conversion to a given state or condition; diminution; conquest; as, the reduction of a body to powder; the reduction of things to order; the reduction of the expenses of government; the reduction of a rebellious province.
  • (n.) The act or process of reducing. See Reduce, v. t., 6. and To reduce an equation, To reduce an expression, under Reduce, v. t.
  • (v. t.) The correction of observations for known errors of instruments, etc.
  • (v. t.) The preparation of the facts and measurements of observations in order to deduce a general result.
  • (v. t.) The process of making a copy of something, as a figure, design, or draught, on a smaller scale, preserving the proper proportions.
  • (v. t.) The bringing of a syllogism in one of the so-called imperfect modes into a mode in the first figure.
  • (v. t.) The act, process, or result of reducing; as, the reduction of iron from its ores; the reduction of aldehyde from alcohol.
  • (v. t.) The operation of restoring a dislocated or fractured part to its former place.

Example Sentences:

  • (1) Direct fetal digitalization led to a reduction in umbilical artery resistance, a decline in the abdominal circumference from 20.3 to 17.8 cm, and resolution of the ascites within 72 h. Despite this dramatic response to therapy, fetal death occurred on day 5 of treatment.
  • (2) Use of the improved operative technique contributed to reduction in number of complications.
  • (3) Following central retinal artery ligation, infarction of the retinal ganglion cells was reflected by a 97 per cent reduction in the radioactively labeled protein within the optic nerve.
  • (4) It is concluded that amlodipine reduces myocardial ischemic injury by mechanism(s) that may involve a reduction in myocardial oxygen demand as well as by positively influencing transmembrane Ca2+ fluxes during ischemia and reperfusion.
  • (5) By 1978, the reduction in incidence of measles will exceed 90%.
  • (6) Osteoporosis is characterized by a reduction in bone density.
  • (7) At pH 7.0, reduction is complete after 6 to 10 h. These results together with an earlier study concerning the positions of the two most readily reduced bonds (Cornell J.S., and Pierce, J.G.
  • (8) A survey carried out two and three years after the launch of the official campaign also showed a reduction in the prevalence of rickets in children taking low dose supplements equivalent to about 2.5 micrograms (100 IU) vitamin D daily.
  • (9) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
  • (10) Maximal covalent binding of [4,5-14C]ronidazole to DNA also required four-electron reduction, consistent with previous studies of the covalent binding of this agent to immobilized sulfhydryl groups [Kedderis et al.
  • (11) Optimum rates of acetylene reduction in short-term assays occurred at 20% O2 (0.2 atm (1 atm = 101.325 kPa] in the gas phase.
  • (12) Meanwhile, reductions in tax allowances on dividends for company shareholders from £5,000 down to £2,000 represent another dent to the incomes of many business owners.
  • (13) Polyribosomes isolated from the livers of rats sacrificed 6 h after treatment with actinomycin D showed a 42% reduction in their capacity to bind anti-RSA Fab'.
  • (14) In view of reports of the reduction of telomeric repeats in human malignant tumors, we measured the lengths of telomeric repeats in 55 primary neuroblastomas.
  • (15) Anatomic and roentgenographic criteria used for the assessment of reduction in ankle fractures are highlighted in this review of ankle trauma.
  • (16) By increasing luminal air pressure from 10 to 20 cm H2O a significant reduction in GBF was observed.
  • (17) The reduction rates of peripheral leukocytes, lung Schiff bases and lung water content were not identical in rats depleted from leukocyte after inhalation injury.
  • (18) The results show that in TMO-treated animals the time to the onset of convulsions, the time to the onset of NADH oxidation-reduction cycles, and the survival time were significantly longer than in the control group.
  • (19) Since the first is balked by the obstacle of deficit reduction, emphasis has turned to the second.
  • (20) The analysis of total seizure days showed a significant reduction during LTG treatment (p less than 0.002).