What's the difference between clearance and release?

Clearance


Definition:

  • (n.) The act of clearing; as, to make a thorough clearance.
  • (n.) A certificate that a ship or vessel has been cleared at the customhouse; permission to sail.
  • (n.) Clear or net profit.
  • (n.) The distance by which one object clears another, as the distance between the piston and cylinder head at the end of a stroke in a steam engine, or the least distance between the point of a cogwheel tooth and the bottom of a space between teeth of a wheel with which it engages.

Example Sentences:

  • (1) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (2) Work on humoral responses has focused on lysozyme, the hemagglutinins (especially in the oyster), and the clearance of certain antigens.
  • (3) It is suggested that the rapid phase is due to clearance of peptides in the circulation which results in a fall to lower blood concentrations which are sustained by slow release of peptide from binding sites which act as a depot.
  • (4) In addition to esophageal manometry, we also performed acid-clearance studies and examined salivary output, acid-neutralizing capacity, and bicarbonate concentration.
  • (5) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
  • (6) Pharmacokinetic parameters, such as these clearances, had large intersubject variations.
  • (7) Mortality, blood clearance and organ distribution of 125I labelled Escherichia coli were determined.
  • (8) Unbound fractions was significantly correlated with serum albumin concentration (r = -0.344, p less than 0.046) and renal clearance (r = 0.394, p less than 0.021) but not with total body clearance or volume of distribution.
  • (9) Renal blood flow was measured in all patients by Hippuran-clearance and xenon-washout.
  • (10) Temelastine produces these species-specific changes by enhancing thyroxine clearance from the circulation in the rat, but not in the dog or mouse.
  • (11) Our study suggests that a major part of the renal antimineralocorticoid activity of spironolactone may be attributable to minor sulfur-containing metabolites or their precursors having a high renal clearance that affords access to their site of activity via the renal tubular fluid.
  • (12) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
  • (13) These results suggest that glomerular IgA are IgA polymers and decreased hepatic clearance of hepatic IgA polymers may be responsible for the glomerular deposition of IgA.
  • (14) Furthermore, the changes in both interstitial fluid and testicular venous blood levels of testosterone do not always parallel those in peripheral venous blood, suggesting that changes in testicular blood flow and peripheral clearance rates of testosterone may also be important in the control of circulating testosterone concentrations.
  • (15) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
  • (16) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
  • (17) [14C]Sucrose biliary clearance increased in treated animals, suggesting an increased permeability of the biliary system to sucrose.
  • (18) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
  • (19) The time to recovery of full consciousness, time to parasite clearance, and mortality were examined with Cox proportional-hazards regression analysis.
  • (20) Tracheal mucus transport rate (TMTR) and quantitative clearance of aerosolized Escherichia coli from the trachea, lung, and air sac were measured in healthy unanesthetized turkeys and in turkeys exposed by aerosol to a La Sota vaccine strain of Newcastle disease virus (NDV).

Release


Definition:

  • (v. t.) To lease again; to grant a new lease of; to let back.
  • (n.) To let loose again; to set free from restraint, confinement, or servitude; to give liberty to, or to set at liberty; to let go.
  • (n.) To relieve from something that confines, burdens, or oppresses, as from pain, trouble, obligation, penalty.
  • (n.) To let go, as a legal claim; to discharge or relinquish a right to, as lands or tenements, by conveying to another who has some right or estate in possession, as when the person in remainder releases his right to the tenant in possession; to quit.
  • (n.) To loosen; to relax; to remove the obligation of; as, to release an ordinance.
  • (n.) The act of letting loose or freeing, or the state of being let loose or freed; liberation or discharge from restraint of any kind, as from confinement or bondage.
  • (n.) Relief from care, pain, or any burden.
  • (n.) Discharge from obligation or responsibility, as from debt, penalty, or claim of any kind; acquittance.
  • (n.) A giving up or relinquishment of some right or claim; a conveyance of a man's right in lands or tenements to another who has some estate in possession; a quitclaim.
  • (n.) The act of opening the exhaust port to allow the steam to escape.

Example Sentences:

  • (1) The fluoride treated specimens released more fluoride than the nontreated ones.
  • (2) In conclusion, in S-rats a glucose-stimulated insulin release is accompanied by an increase in IBF, but this is not observed in P-rats.
  • (3) These are typically runaway processes in which global temperature rises lead to further releases of CO², which in turn brings about more global warming.
  • (4) This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of which cause significant release of [3H]5-HT from rat brain synaptosomes.
  • (5) The vascular endothelium is capable of regulating tissue perfusion by the release of endothelium-derived relaxing factor to modulate vasomotor tone of the resistance vasculature.
  • (6) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
  • (7) In contrast, the effects of deltamethrin and cypermethrin promote transmitter release by a Na+ dependent process.
  • (8) However, direct measurements of mediator release should be carried out to reach a firm conclusion.
  • (9) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
  • (10) During recovery glucose uptake was reduced and citrate release was unaffected.
  • (11) Bradykinin also stimulated arachidonic acid release in decidual fibroblasts, an effect which was potentiated in the presence of epidermal growth factor (EGF), but which was not accompanied by an increase in PGF2 alpha production.
  • (12) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
  • (13) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
  • (14) It is suggested that the normal cyclical release of LH is inhibited in PCO disease by a negative feedback by androgens to the hypothalamus or the pituitary, and that wedge resection should be reserved for patients in whom other forms of treatment have failed.
  • (15) Results suggest that Cd-MT is reabsorbed and broken down by kidney tubule cells in a physiological manner with possible subsequent release of the toxic cadmium ion.
  • (16) The latter result indicates that the dexamethasone block is upstream from release of esterified arachidonic acid.
  • (17) Treatment of the bound F1-ATPase with 4-chloro-7-nitrobenzofurazan prevented complete release of the enzyme by ATP.
  • (18) Glucose release from these samples was highly correlated with starch gelatinization (r2 = .99).
  • (19) Furthermore, H-7 enhanced the effect of thrombin on AA release.
  • (20) Because it has been suggested that the lathyrogen, BAPN, may stimulate the release of proteases, the protease inhibitors Trasylol and epsilon-aminocaproic acid (EACA) were given alone or in combination to BAPN-treated rats.