(n.) The act of clearing; as, to make a thorough clearance.
(n.) A certificate that a ship or vessel has been cleared at the customhouse; permission to sail.
(n.) Clear or net profit.
(n.) The distance by which one object clears another, as the distance between the piston and cylinder head at the end of a stroke in a steam engine, or the least distance between the point of a cogwheel tooth and the bottom of a space between teeth of a wheel with which it engages.
Example Sentences:
(1) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(2) Work on humoral responses has focused on lysozyme, the hemagglutinins (especially in the oyster), and the clearance of certain antigens.
(3) It is suggested that the rapid phase is due to clearance of peptides in the circulation which results in a fall to lower blood concentrations which are sustained by slow release of peptide from binding sites which act as a depot.
(4) In addition to esophageal manometry, we also performed acid-clearance studies and examined salivary output, acid-neutralizing capacity, and bicarbonate concentration.
(5) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
(6) Pharmacokinetic parameters, such as these clearances, had large intersubject variations.
(7) Mortality, blood clearance and organ distribution of 125I labelled Escherichia coli were determined.
(8) Unbound fractions was significantly correlated with serum albumin concentration (r = -0.344, p less than 0.046) and renal clearance (r = 0.394, p less than 0.021) but not with total body clearance or volume of distribution.
(9) Renal blood flow was measured in all patients by Hippuran-clearance and xenon-washout.
(10) Temelastine produces these species-specific changes by enhancing thyroxine clearance from the circulation in the rat, but not in the dog or mouse.
(11) Our study suggests that a major part of the renal antimineralocorticoid activity of spironolactone may be attributable to minor sulfur-containing metabolites or their precursors having a high renal clearance that affords access to their site of activity via the renal tubular fluid.
(12) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(13) These results suggest that glomerular IgA are IgA polymers and decreased hepatic clearance of hepatic IgA polymers may be responsible for the glomerular deposition of IgA.
(14) Furthermore, the changes in both interstitial fluid and testicular venous blood levels of testosterone do not always parallel those in peripheral venous blood, suggesting that changes in testicular blood flow and peripheral clearance rates of testosterone may also be important in the control of circulating testosterone concentrations.
(15) Isolated renal tubules and renal clearance techniques were used to characterize the renal handling of 2-deoxy-D-galactose (2-d-Gal) by the winter flounder (Pseudopleuronectes americanus).
(16) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
(17) [14C]Sucrose biliary clearance increased in treated animals, suggesting an increased permeability of the biliary system to sucrose.
(18) In view of its significant effects on drug metabolizing enzymes and clearance mechanisms, it is important to know its disposition characteristics.
(19) The time to recovery of full consciousness, time to parasite clearance, and mortality were examined with Cox proportional-hazards regression analysis.
(20) Tracheal mucus transport rate (TMTR) and quantitative clearance of aerosolized Escherichia coli from the trachea, lung, and air sac were measured in healthy unanesthetized turkeys and in turkeys exposed by aerosol to a La Sota vaccine strain of Newcastle disease virus (NDV).
(a.) Withdraw from general intercourse or notice; in retirement or secrecy; secluded.
(a.) Faithful to a secret; not inclined to divulge or betray confidence; secretive.
(a.) Separate; distinct.
(a.) Something studiously concealed; a thing kept from general knowledge; what is not revealed, or not to be revealed.
(a.) A thing not discovered; what is unknown or unexplained; a mystery.
(a.) The parts which modesty and propriety require to be concealed; the genital organs.
(v. t.) To keep secret.
Example Sentences:
(1) In the absence of atrial dilatation there was minimal stimulus for ANF secretion.
(2) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(3) We have investigated a physiological role of endogenous insulin on exocrine pancreatic secretion stimulated by a liquid meal as well as exogenous secretin and cholecystokinin octapeptide (CCK-8) in conscious rats.
(4) To examine the central nervous system regulation of duodenal bicarbonate secretion, an animal model was developed that allowed cerebroventricular and intravenous injections as well as collection of duodenal perfusates in awake, freely moving rats.
(5) The present study was therefore carried out to specify further which type of adrenoceptor is involved in lithium-induced hyperglycaemia and inhibition of insulin secretion.
(6) Significant increases in acid secretion were observed without changes in cyclic nucleotides.
(7) In summary, GABAergic tone did not effect basal acid secretion in anesthetized rats.
(8) The effects of glucagon-induced insulin secretion upon this lipid regulation are discussed that may resolve conflicting reports in the literature are resolved.
(9) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(10) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(11) "They wanted to pass it almost like a secret negotiation," she said.
(12) The secretion of GH as measured by increased plasma level, in response to oral administration of 500 mg L-dopa or 30 min-infusion of arginine, was not modified by prior intravenous administration of 200 micrograms GH-releasing hormone (GHRH).
(13) Short incubations with heparin (5 min) caused a release of the enzyme into the media, while longer incubations caused a 2-8-fold increase in net lipoprotein lipase secretion which was maximal after 2-16 h depending on cell type, and persisted for 24 h. The effect of heparin was dose-dependent and specific (it was not duplicated by other glycosaminoglycans).
(14) This experimental system allows separation of three B lymphocyte developmental stages: early differentiation in vitro, progression to IgM secretion in vivo, and late differentiation dependent upon mature T lymphocytes in vivo.
(15) These results provide evidence that trait selection can change gonadotrophin receptor concentration and the dynamics of hormone secretion during the oestrous cycle of the mouse.
(16) Caries-related bacteriological and biochemical factors were studied in 12 persons with low and 11 persons with normal salivary-secretion rates before and after a four-week period of frequent mouthrinses with 10% sorbitol solution (adaptation period).
(17) The sites of action for somatostatin and epinephrine to inhibit insulin secretion have been reported to be exclusively in the exocytotic pathway.
(18) Since intracellular Ca2+ seems to play a role in stimulus-secretion coupling and ion movements, several aspects of Ca2+ homeostasis have been investigated in CF.
(19) The Metoclopramide-induced secretion of prolactin and aldosterone was blunted in 6 patients pretreated with 200 mg ibopamine.
(20) On the basis of obtained data on the uniformity of chemical compounds of the secretion of glands belonging to different groups their common origin has been suggested.