What's the difference between cleavage and joint?

Cleavage


Definition:

  • (n.) The act of cleaving or splitting.
  • (n.) The quality possessed by many crystallized substances of splitting readily in one or more definite directions, in which the cohesive attraction is a minimum, affording more or less smooth surfaces; the direction of the dividing plane; a fragment obtained by cleaving, as of a diamond. See Parting.
  • (n.) Division into laminae, like slate, with the lamination not necessarily parallel to the plane of deposition; -- usually produced by pressure.

Example Sentences:

  • (1) It is possible that the high level of radiolabeled phospholipid found in the plasma membrane arose via the de novo pathway following the cleavage of an acyl group as we have found cytidine diphosphocholine phosphotransferase in the plasma membrane fraction (Wang, P., DeChatelet, L.R., and Waite, M. (1977) Biochim.
  • (2) Release of nsP4 from P1234 appears to be independent of the other cleavages and occurs primarily immediately after translation.
  • (3) A broad specificity of LipDH was observed for the glycine cleavage system.
  • (4) It is the action of this protease that releases the enzyme from the membrane, as shown by the observations that protease inhibitors decreased the amount of solubilization of the enzyme, and the enzyme remaining in the membrane after heating showed much less proteolytic cleavage than that which was released.
  • (5) One of the proteases obtained was found to catalyse cleavage on the COOH-side of peptide sequences containing consecutive hydrophobic and basic residues.
  • (6) The results show that in both viral DNAs cleavage occurs at the origin and at one additional site which shows striking sequence homology with the origin region.
  • (7) These results would suggest that N-terminal acetylation and C-terminal proteolytic cleavage are important post-translational modifications of the forms of Amia beta-endorphin.
  • (8) We speculate that this cleavage event is catalyzed by either a cryptic potyviral proteinase that requires a host factor or subcellular environment for activation, or possibly a host proteinase.
  • (9) The relative cleavage frequency at the first glycosidic bond counting from the nonreducing end of the substrate increases with increasing substrate concentration.
  • (10) An analysis of the triple helical stabilities of these cleavage site regions as reflected by their imino acid contents fails to yield a correlation between reactivity and triple helical stability.
  • (11) We found that the closer location of Mg2+ to the beta-phosphoryl group than to the alpha- or gamma-phosphoryl group was effective in weakening the P-O bond at which the cleavage of ATP catalyzed by most enzymes takes place.
  • (12) Subsequently, due to the rotation of the original polar axis in one hemisphere, the third cleavage plane through one half of the egg is transverse to the third cleavage plane through the other half.
  • (13) It is concluded that in this cell type (i) somatostatin-14 is exclusively generated by dibasic cleavage at the Arg-2-Lys-1 site of the intact precursor with concomitant production of prosomatostatin[1-76], and (ii) no direct interactions between the monobasic and dibasic processing domains occur.
  • (14) The amount of cleavage products depends on the excess of H2O2 used.
  • (15) To determine which enzymes are responsible for the processing cleavages of ribosomal RNA transcripts in Escherichia coli, we constructed a mutant strain lacking RNAase III and containing a thermolabile RNAase P. At the nonpermissive temperature, this strain accumulates a novel "19S" RNA species which contains 17S precursor rRNA sequences covalently linked to tRNA sequences transcribed from the ribosomal RNA spacer region between the 16S and the 23S rRNA cistrons.
  • (16) The cleavage of beta-cyclodextrine by sodium periodate at the seven 2-3 diols of the glucose unit gives rise to the polyaldehyde 1, used to modify alpha-amylase.
  • (17) The possibility that mammalian DNA topoisomerase II is an intracellular target which mediates drug-induced DNA breaks is supported by the following studies using 4'-(9-acridinylamino)methane-sulfon-m-anisidide (m-AMSA): (a) a single m-AMSA-dependent DNA cleavage activity copurified with calf thymus DNA topoisomerase II activity at all chromatographic steps of the enzyme purification; (b) m-AMSA-induced DNA cleavage by this purified activity resulted in the covalent attachment of protein to the 5'-ends of the DNA via a tyrosyl phosphate bond.
  • (18) This single substitution was sufficient to abolish all detectable cleavage of the gp160 envelope precursor polypeptide as well as virus infectivity.
  • (19) Certain RNA molecules can mediate their own cleavage or splicing or act as enzymes to promote reactions on substrate RNA molecules.
  • (20) The envelope glycoprotein of human immunodeficiency virus consists of two subunits, designated gp120 and gp41, derived from the cleavage of a precursor polypeptide gp160.

Joint


Definition:

  • (n.) The place or part where two things or parts are joined or united; the union of two or more smooth or even surfaces admitting of a close-fitting or junction; junction as, a joint between two pieces of timber; a joint in a pipe.
  • (n.) A joining of two things or parts so as to admit of motion; an articulation, whether movable or not; a hinge; as, the knee joint; a node or joint of a stem; a ball and socket joint. See Articulation.
  • (n.) The part or space included between two joints, knots, nodes, or articulations; as, a joint of cane or of a grass stem; a joint of the leg.
  • (n.) Any one of the large pieces of meat, as cut into portions by the butcher for roasting.
  • (n.) A plane of fracture, or divisional plane, of a rock transverse to the stratification.
  • (n.) The space between the adjacent surfaces of two bodies joined and held together, as by means of cement, mortar, etc.; as, a thin joint.
  • (n.) The means whereby the meeting surfaces of pieces in a structure are secured together.
  • (a.) Joined; united; combined; concerted; as joint action.
  • (a.) Involving the united activity of two or more; done or produced by two or more working together.
  • (a.) United, joined, or sharing with another or with others; not solitary in interest or action; holding in common with an associate, or with associates; acting together; as, joint heir; joint creditor; joint debtor, etc.
  • (a.) Shared by, or affecting two or more; held in common; as, joint property; a joint bond.
  • (v. t.) To unite by a joint or joints; to fit together; to prepare so as to fit together; as, to joint boards.
  • (v. t.) To join; to connect; to unite; to combine.
  • (v. t.) To provide with a joint or joints; to articulate.
  • (v. t.) To separate the joints; of; to divide at the joint or joints; to disjoint; to cut up into joints, as meat.
  • (v. i.) To fit as if by joints; to coalesce as joints do; as, the stones joint, neatly.

Example Sentences:

  • (1) It is likely that trunk mobility is necessary to maintain integrity of SI joint and that absence of such mobility compromises SI joint structure in many paraplegics.
  • (2) The sequential histopathologic alterations in femorotibial joints of partial meniscectomized male and female guinea pigs were evaluated at 1, 2, 3, 6, and 12 weeks post-surgery.
  • (3) Compared with conservative management, better long-term success (determined by return of athletic soundness and less evidence of degenerative joint disease) was achieved with surgical curettage of elbow subchondral cystic lesions.
  • (4) On Friday, a spokesperson for China’s foreign ministry appeared to confirm those fears, telling reporters that the joint declaration, a deal negotiated by London and Beijing guaranteeing Hong Kong’s way of life for 50 years, “was a historical document that no longer had any practical significance”.
  • (5) Based upon the analysis of 1015 case records of patients, aged 16-70, with different hip joint pathology types, carried out during 1985-1990, there were revealed mistakes and complications after reconstructive-restorative operations.
  • (6) By measurement and analysis of the changes in carpal angles and joint spaces, carpal instability was discovered in 41 fractures, an incidence of 30.6%.
  • (7) Apart from their pathogenic significance, these results may have some interest for the clinical investigation of patients with joint diseases.
  • (8) Formation of the functional contour plaster bandage within the limits of the foot along the border of the fissure of the ankle joint with preservation of the contours of the ankles 4-8 weeks after the treatment was started in accordance with the severity of the fractures of the ankles in 95 patients both without (6) and with (89) dislocation of the bone fragments allowed to achieve the bone consolidation of the ankle fragments with recovery of the supportive ability of the extremity in 85 (89.5%) of the patients, after 6-8 weeks (7.2%) in the patients without displacement and after 10-13 weeks (11.3%) with displacement of the bone fragments of the ankles.
  • (9) Clinical evaluation of passive range of motion, antero-posterior laxity and the appearance of the joint space showed little or no difference between the reconstruction methods.
  • (10) This system may serve as a model to explain the mechanisms by which cells accumulate in inflamed joints.
  • (11) On the basis of these data, the computer, upon the basis of a program specially developed for this purpose, automatically calculates the corresponding amount of negative-points, which parallels the severity of the joint changes, i.e.
  • (12) The prognosis of meningococcal arthritis is excellent and joint sequelae are rare.
  • (13) In the anatomy laboratory we looked for an alternative approach to the glenohumeral joint which would accommodate these difficulties.
  • (14) These two enzymes may act jointly in filling up the gaps along the DNA molecule and elongating the DNA chain.
  • (15) The results of conventional sciatic nerve stretching tests are usually evaluated regardless of patient age, gender or movements of the hip joint and spine.
  • (16) The correlation of posterior intervertebral (facet) joint tropism (asymmetry), degenerative facet disease, and intervertebral disc disease was reviewed in a retrospective study of magnetic resonance images of the lumbar spine from 100 patients with complaints of low back pain and sciatica.
  • (17) Hypermobility and instability following injury and degenerative joint disease is poorly understood and often not recognized as the cause of the patients symptoms.
  • (18) One middle carpal joint of each horse was injected 3 times with 100 mg of 6-alpha-methylprednisolone acetate, at 14-day intervals.
  • (19) In a clear water reservoir built in ready construction after a working-period of five months quite a lot of slime could be found on the expansion joint filled with tightening compound on the base of Thiokol.
  • (20) Cable argued that the additional £30bn austerity proposed by the chancellor after 2015 went beyond the joint coalition commitment to eradicate the structural part of the UK's current budget deficit – the part of non-investment spending that will not disappear even when the economy has fully emerged from the recession of 2008-09.