(n.) The quality possessed by many crystallized substances of splitting readily in one or more definite directions, in which the cohesive attraction is a minimum, affording more or less smooth surfaces; the direction of the dividing plane; a fragment obtained by cleaving, as of a diamond. See Parting.
(n.) Division into laminae, like slate, with the lamination not necessarily parallel to the plane of deposition; -- usually produced by pressure.
Example Sentences:
(1) It is possible that the high level of radiolabeled phospholipid found in the plasma membrane arose via the de novo pathway following the cleavage of an acyl group as we have found cytidine diphosphocholine phosphotransferase in the plasma membrane fraction (Wang, P., DeChatelet, L.R., and Waite, M. (1977) Biochim.
(2) Release of nsP4 from P1234 appears to be independent of the other cleavages and occurs primarily immediately after translation.
(3) A broad specificity of LipDH was observed for the glycine cleavage system.
(4) It is the action of this protease that releases the enzyme from the membrane, as shown by the observations that protease inhibitors decreased the amount of solubilization of the enzyme, and the enzyme remaining in the membrane after heating showed much less proteolytic cleavage than that which was released.
(5) One of the proteases obtained was found to catalyse cleavage on the COOH-side of peptide sequences containing consecutive hydrophobic and basic residues.
(6) The results show that in both viral DNAs cleavage occurs at the origin and at one additional site which shows striking sequence homology with the origin region.
(7) These results would suggest that N-terminal acetylation and C-terminal proteolytic cleavage are important post-translational modifications of the forms of Amia beta-endorphin.
(8) We speculate that this cleavage event is catalyzed by either a cryptic potyviral proteinase that requires a host factor or subcellular environment for activation, or possibly a host proteinase.
(9) The relative cleavage frequency at the first glycosidic bond counting from the nonreducing end of the substrate increases with increasing substrate concentration.
(10) An analysis of the triple helical stabilities of these cleavage site regions as reflected by their imino acid contents fails to yield a correlation between reactivity and triple helical stability.
(11) We found that the closer location of Mg2+ to the beta-phosphoryl group than to the alpha- or gamma-phosphoryl group was effective in weakening the P-O bond at which the cleavage of ATP catalyzed by most enzymes takes place.
(12) Subsequently, due to the rotation of the original polar axis in one hemisphere, the third cleavage plane through one half of the egg is transverse to the third cleavage plane through the other half.
(13) It is concluded that in this cell type (i) somatostatin-14 is exclusively generated by dibasic cleavage at the Arg-2-Lys-1 site of the intact precursor with concomitant production of prosomatostatin[1-76], and (ii) no direct interactions between the monobasic and dibasic processing domains occur.
(14) The amount of cleavage products depends on the excess of H2O2 used.
(15) To determine which enzymes are responsible for the processing cleavages of ribosomal RNA transcripts in Escherichia coli, we constructed a mutant strain lacking RNAase III and containing a thermolabile RNAase P. At the nonpermissive temperature, this strain accumulates a novel "19S" RNA species which contains 17S precursor rRNA sequences covalently linked to tRNA sequences transcribed from the ribosomal RNA spacer region between the 16S and the 23S rRNA cistrons.
(16) The cleavage of beta-cyclodextrine by sodium periodate at the seven 2-3 diols of the glucose unit gives rise to the polyaldehyde 1, used to modify alpha-amylase.
(17) The possibility that mammalian DNA topoisomerase II is an intracellular target which mediates drug-induced DNA breaks is supported by the following studies using 4'-(9-acridinylamino)methane-sulfon-m-anisidide (m-AMSA): (a) a single m-AMSA-dependent DNA cleavage activity copurified with calf thymus DNA topoisomerase II activity at all chromatographic steps of the enzyme purification; (b) m-AMSA-induced DNA cleavage by this purified activity resulted in the covalent attachment of protein to the 5'-ends of the DNA via a tyrosyl phosphate bond.
(18) This single substitution was sufficient to abolish all detectable cleavage of the gp160 envelope precursor polypeptide as well as virus infectivity.
(19) Certain RNA molecules can mediate their own cleavage or splicing or act as enzymes to promote reactions on substrate RNA molecules.
(20) The envelope glycoprotein of human immunodeficiency virus consists of two subunits, designated gp120 and gp41, derived from the cleavage of a precursor polypeptide gp160.
Valley
Definition:
(n.) The space inclosed between ranges of hills or mountains; the strip of land at the bottom of the depressions intersecting a country, including usually the bed of a stream, with frequently broad alluvial plains on one or both sides of the stream. Also used figuratively.
(n.) The place of meeting of two slopes of a roof, which have their plates running in different directions, and form on the plan a reentrant angle.
(n.) The depression formed by the meeting of two slopes on a flat roof.
Example Sentences:
(1) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(2) We always feel like it's Hobbitshire – a green valley where nothing happens."
(3) In 1971 the Fountain Valley (Calif.) High School established a program at Fairview State Hospital in Costa Mesa.
(4) In primary culture, CSM cells attached to the culture vessels by 48 to 72 h, proliferated by 3 to 7 d, and reached confluency by 14 to 17 d with a "hill-and-valley" pattern.
(5) Although selenium deficiency in livestock is consequently now rare in Oregon, selenium-deficient soils and attendant selenium deficiency conditions have been reported near the Kesterson Wildlife Refuge in the Northern part of the San Joaquin Valley, California, where, paradoxically, selenium toxicity in wildfowl, nesting near evaporation ponds, occurred and attracted wide attention.
(6) The first problem facing Calderdale is sheep-rustling Happy Valley – filmed around Hebden Bridge, with its beautiful stone houses straight off the pages of the Guardian’s Lets Move To – may be filled with rolling hills and verdant pastures, but the reality of rural issues are harsh.
(7) Even the landscape is secretive: vast tracts of crown land and hidden valleys with nothing but a dead end road and lonely farmhouse, with a tractor and trailer pulled across the farmyard for protection.
(8) 2589 sera from pathology laboratories in towns in the Murray Valley gave additional evidence of community immunity to flaviviruses and suggested some increase in the proportion reactive between January and May 1974.
(9) Wastewater from Mexico city is used to irrigate over 85 000 hectares, mainly of fodder and cereal crops in the Mezquital Valley.
(10) By means of immunoreactivity for spot 35 protein, a novel cerebellar Purkinje cell-specific protein, the regional heterogeneity among non-pigmented ciliary epithelial cells of rats was demonstrated with reference to the antero-posterior and crest-valley directions of individual ciliary epithelial folds in immature and mature eyes.
(11) Compounds 3a and 3c exhibited significant activity against vaccinia virus in vitro, whereas 4a was effective against Rift Valley fever virus in mice.
(12) Two “Belgian journalists” had been in the Panjshir valley of northern Afghanistan for weeks, supposedly waiting to interview Ahmad Shah Massoud, the so-called Lion of the Panjshir, leader of the anti-Taliban Northern Alliance, an al-Qaida adversary.
(13) At the World Economic Forum in Davos last week, Netanyahu declared he would not “uproot a single settler” from the Jordan Valley.
(14) The antibody response against flaviviruses tick-borne encephalitis (TBE), Kyasanur Forest disease (KFD), Murray Valley encephalitis (MVE), West Nile fever (WNF), Japanese B encephalitis (JE), dengue 2 (DEN-2), and yellow fever (YF) was studied in humans after administration of an inactivated TBE virus vaccine.
(15) The data discussed in this article were gathered through use of a retrospective cohort survey five years following a major flood in the Wyoming Valley of Pennsylvania.
(16) A recent study of foetal alcohol syndrome in the Fitzroy Valley, in remote Western Australia, found that 120 out of 1,000 children born in the largely Aboriginal community were affected by the condition, which impairs brain development and decision making and is connected with high rates of involvement in the justice system.
(17) The 5' non-coding region of the genomes of 11 isolates of Murray Valley encephalitis virus from Australia and Papua New Guinea were examined by primer extension sequencing.
(18) As part of a concerted effort to avoid the in danger listing, the Queensland government came up with an alternative plan to dump the sediment within an enclosed area of the Caley Valley wetlands, which is considered nationally important habitat for more than 15 species of migratory birds.
(19) The list is split between on and off-screen talent, including Sherlock producer Sue Vertue, the writer of Last Tango in Halifax and Happy Valley, Sally Wainwright, and Elisabeth Murdoch , founder of MasterChef producer Shine.
(20) Non-discrimination laws chart Although the decisive manner in which leaders from Silicon Valley and the business community rallied against – and ultimately helped change – the Indiana law marked a major turning point, Talbot conceded that the project itself is unfinished.