(n.) A period in human life in which some great change is supposed to take place in the constitution. The critical periods are thought by some to be the years produced by multiplying 7 into the odd numbers 3, 5, 7, and 9; to which others add the 81st year.
(n.) Any critical period.
Example Sentences:
(1) The purpose of this investigation was to evaluate the relationship between climacteric status and health symptoms across age cohorts in 522 African American women aged 25-75.
(2) These data suggested that estrogen may be able to control the function of the autonomic nervous system in climacteric woman.
(3) Researchers have failed to distinguish between the spontaneous symptoms of women subject to climacteric disturbances and the sensations others admit to on questioning.
(4) The TAA component of CaCx common for all clinical stages, irrespective of climacteric states, was partially purified by subjecting postmeno CaCx, Stage II to gel filtration on Sephadex G-200.
(5) Considering in detail the results some immediate clinical and metabolic consequences come out: namely, want of Ca is prevailing in women and just in the critical age classes (20-40 and 50-59 years, that is in fertile and climacteric ages).
(6) Although the evidence is not conclusive, overall many sexual changes seem to occur in the climacteric years.
(7) The statement that the human female climacteric represents a pathologic rather than a physiologic state should not generate antagonistic counter-arguments; rather, it should be recognized as a challenge for the identification, prediction, and prevention of organic disease in the woman during the climacteric and after.
(8) It is argued that this differential recovery of fructose 2,6-bisphosphate undermines claims that the amount of this compound increases at the climacteric.
(9) It has also been shown that too low doses of ERT are able to exert therapeutical effects on some climacteric symptoms but not on bone and compounds exerting synergic actions with ERT on bone without effects on other organs could be useful.
(10) Bone mass, calcium and lipid metabolism, climacteric symptoms, bleeding, blood pressure, and weight changes were studied in 62 healthy postmenopausal women at 3-month intervals throughout 2 years of treatment with continuous estradiol valerate (2 mg) plus cyproterone acetate (1 mg), sequential estradiol valerate (2 mg) plus levonorgestrel (75 micrograms), or placebo.
(11) Risk factors (obesity, hypertension, diabetes mellitus) for endometrial cancer were found in 38% of MB and in 20% of climacteric metrorrhagia.
(12) Of climacteric disturbances should be spoken only after menopause.
(13) Climacteric symptoms and hot flushes were significantly reduced in both hormone groups compared with the placebo group.
(14) The endocrinological changes of the climacteric have been defined by studying the concentrations of follicle-stimulating hormone (FSH), luteinising hormone (LH), androstenedione, testosterone, oestrone, and oestradiol in 60 normal postmenopausal women of different menopausal ages.
(15) In climacteric syndrome in a narrow sense (i.e., dysautonomic type), each complaint may also have its specific endocrinological cause.
(16) Similarly, attitudes to the climacteric vary across cultural origins, especially with regard to husband-wife relationships.
(17) Significant changes in carbon dioxide production and oxygen consumption were still evident well into the climacteric.
(18) The selection criterion was the evidence of risk factors for endometrial carcinoma, climacteric bleedings (obesity, late menopause, high blood pressure, diabetes), or endometriotropic estrogen therapy in the postmenopause.
(19) This can be probably explained for the genital district by the hyperestrogenic situation that the climacteric woman experiences and by the promoting effect that estrogens have on the neoplastic growth.
(20) Our data imply that climacteric symptoms are not accompanied by changes in the production of prostacyclin and thromboxane A2.
Menopause
Definition:
(n.) The period of natural cessation of menstruation. See Change of life, under Change.
Example Sentences:
(1) Osteoporosis and its treatment have attracted much attention in recent years, especially since the widespread recognition of its association with the menopause.
(2) Today the physician who treats women with emotional problems during menopause cannot function solely as a psychotherapist; he must deal with both their soma and psyche.
(3) The difference in the timing of the change in FSH and LH concentrations was related not only to chronological age but also to the number of years before the menopause.
(4) Women in the late pre-menopausal group who were clinically depressed had significantly higher levels of TSH and triiodothyronine than other subjects.
(5) A comparative evaluation of these data suggest that hormone independent cells are present in the cervical crypts of late menopause women and that a cyclic change of hormone dependent cells may occur in fertile women, analogous to the cyclic changes of endometrial mucosa.
(6) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(7) The relationships between the menopause and risk factors for ischaemic heart disease are complex, which may be one reason for the contradictory results when relating menopausal age to the incidence of ischaemic heart disease.
(8) The modifying effect of estrogen receptor status on the relation of obesity to node involvement was apparent in pre- and post-menopausal women.
(9) The gonadally unresponsive patients had either pituitary tumours or premature menopause.
(10) Quantitative variation of the lysosomes in the epithelium of the human uterine tube in the menstrual cycle and in post-menopausal period.
(11) In contrast, none of 16 women who had reached menopause and only two of 21 men required oral absorption of dietary or prescribed iron for the amount of blood iron donated.
(12) To determine if menopausal status influenced the response to exercise, we analyzed the difference between groups for premenopausal and postmenopausal subjects separately.
(13) In pre-menopausal women no association has been found between increased height and weight as risk factors for breast cancer.
(14) Among breast cancer women, PRL increase was irrespective of the type of surgery, the histology of the tumor and the menopausal status.
(15) The same two estrogens were given to women with natural menopause, along with utrogestan, a micronized progesterone.
(16) It is highly probable that the menopause, spontaneous or above all artificially induced, is a cardiovascular risk factor.
(17) It is always purified on Sephadex G-100 immediately before addition to the RIA and in this manner it may be used for up to 2 month after labeling when kept at --20 degrees C. Curves obtained at different dilutions of the H-FSH Standard, carried out with phosphosaline buffer, pH 7.4-7.8 (PBS) containing 1 % human serum albumin, or with horse plasma, of with PBS containing 0,25 % serum from non-immune rabbits (RIA Buffer) have been compared iwth those abtained by serial dilutions of sera from post-menopausal with these diluents.
(18) Three women in generation IV have developed pre-menopausal breast cancer.
(19) None of the variables examined emerged as being significantly associated with PA when data from pre-menopausal patients were used.
(20) Estrogen receptors are more frequently found in post-menopausal women than in women who are still menstruating.