(n.) A concretion or coagulation; esp. a soft, slimy, coagulated mass, as of blood; a coagulum.
(v. i.) To concrete, coagulate, or thicken, as soft or fluid matter by evaporation; to become a cot or clod.
(v. t.) To form into a slimy mass.
Example Sentences:
(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) A cDNA library prepared from human placenta has been screened for sequences coding for factor XIIIa, the enzymatically active subunit of the factor XIII complex that stabilizes blood clots through crosslinking of fibrin molecules.
(3) Congenitally deficient plasmas were used as the substrate for the measurement of procoagulant activities in a one-stage clotting assay.
(4) The risk of total occlusion and clot formation in the renal artery after subintimal injection is high.
(5) After 30 min incubation, blood clotting was observed in all 8 experiments with heparin concentrations of 0 and 1 U per ml; in 3 of 8 with 2 U per ml; and in none with greater than or equal to 3 U per ml.
(6) Purpura fulminans is the cutaneous manifestation of acute activation of the clotting mechanism resulting in massive hemorrhage due to an intravascular consumption coagulopathy.
(7) Electron microscopy showed that the clots consist mainly of a suspension of individual fibers, in contrast to clots made from native fibrinogen, which are highly branched.
(8) In testing the hypothesis that Lp(a) can competitively inhibit plasma clot lysis mediated by plasmin, the present study shows that Lp(a) significantly enhanced plasma clot lysis mediated by streptokinase or t-PA.
(9) After adding 125I-labeled fibrinogen to plasma, clots were made by adding thrombin and calcium and were then resuspended in normal plasma containing various concentrations of JTPI-1.
(10) Hematoma clot weighing 10 grams was removed through emergency craniotomy, followed by external decompression.
(11) These data suggest that, in addition to platelet activation, abnormalities of blood clotting, and particularly reduction of antithrombin III, may play a role in the thrombotic tendency associated with homocystinuria.
(12) is related to the presence of adherent clots along cerebral arteries and when severe may lead to cerebral infarction.
(13) Certain of the schistosomes were covered with a dense mass of interconnected blood platelets resembling a temporary haemostatic plug but not a blood clot.
(14) Concanavalin A was employed to study the role of platelet membrane glycoproteins in platelet-fibrin interactions during clot formation.
(15) Venous thrombosis occurred in 7 patients (17.5%) in the Kabi 2165 group, including two high, potentially emboligenic, localizations (5%), and in 4 patients (10%) in the standard heparin group, including 2 potentially emboligenic clots (5%).
(16) The main objective of these experiments was to develop and characterize a new experimental model of venous thrombosis, and determine whether a combination of vascular wall damage (crushing with hemostat clamps) and prolonged stasis produced more reproducible clots than prolonged stasis per se.
(17) The assay shows strong correlation with the immunologic assay for factor XIII catalytic subunit a (r = 0.94), the factor XIII dansylcadaverine assay (r = 0.83), and the factor XIII clot solubility test.
(18) Unlike thrombin, the newly isolated kallikrein-like enzyme did not cause formation of a fibrin clot when fibrinogen was mixed with the enzyme.
(19) It has to be assumed that in calves with respiratory distress syndrome--in analogy to pulmonary immaturity--the blood clotting mechanism is not yet fully developed.
(20) Five other patients with water-insoluble paraproteins were tested; two were clot-inhibitory.
Embolus
Definition:
(n.) Something inserted, as a wedge; the piston or sucker of a pump or syringe.
(n.) A plug of some substance lodged in a blood vessel, being brought thither by the blood current. It consists most frequently of a clot of fibrin, a detached shred of a morbid growth, a globule of fat, or a microscopic organism.
Example Sentences:
(1) Local embolism, vertebral distal-stump embolism, the dynamics of hemorrhagic infarction and embolus-in-transit are briefly described.
(2) Paradoxical embolus to the right coronary artery was demonstrated premorbidly and at autopsy.
(3) The case of a patient with a hepatic vein bullet embolus complicating a left ventricular gunshot injury is described.
(4) It was concluded that the mixture is much more satisfactory than the conventional cyanoacrylates as an embolus material in vitro.
(5) There was a 12.6% incidence of pulmonary embolism, but only 1.9% of all patients developed a symptomatic pulmonary embolus.
(6) The common lung or pulmonary perfusion scan using macroaggregates of albumin or microspheres radiolabeled also gives information as to the presence of thrombosis of embolus within the pulmonary arteries, by showing the effect upon the perfusion pattern.
(7) A deep venous thrombosis or pulmonary embolus was found in 1.7% and was no less common in the 25% of the patients who received pharmacologic anticoagulation.
(8) If the source of the embolus can be located, medical or surgical therapy may be able to prevent the occurrence of further strokes.
(9) The total incidence of postoperative pulmonary embolus was 3.2%, with two-thirds asymptomatic and one-third symptomatic pulmonary emboli.
(10) A missile embolus, an extremely rare lesion, presents an unusual and challenging problem for the clinician.
(11) Failure to define a source of embolus kept them in the category of IUC.
(12) Anticoagulants have not been administered postoperatively, and one patient has had a systemic embolus.
(13) Low AA and low H-AA (Pattern D) developed in sera of eight patients with thrombophlebitis and seven patients with pulmonary embolus.
(14) Many patients who suffer a massive pulmonary embolus die despite emergent therapy.
(15) While traditional causes of occlusion (saddle embolus and thrombosis) are the most frequent, vasculitis and hypercoagulable states have recently been suggested as etiologies.
(16) In 9 cases, it was an air embolus, in 4 others an atheromatous embolus.
(17) The thrombolytic and pharmacokinetic properties of staphylokinase were compared with those of streptokinase in hamsters with a pulmonary embolus produced from human plasma or from hamster plasma, and in rabbits with a jugular vein blood clot produced from rabbit blood.
(18) From this an embolus may detach to the right hemisphere of the brain resulting in left sided hemiplegia.
(19) The mortality with modern therapy was 12%, and the major complication was cerebral embolus.
(20) In Group A the detection of air embolus varied from 6% using an oesophageal stethoscope to 58% by the Doppler method.