(1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(2) A cDNA library prepared from human placenta has been screened for sequences coding for factor XIIIa, the enzymatically active subunit of the factor XIII complex that stabilizes blood clots through crosslinking of fibrin molecules.
(3) Congenitally deficient plasmas were used as the substrate for the measurement of procoagulant activities in a one-stage clotting assay.
(4) The risk of total occlusion and clot formation in the renal artery after subintimal injection is high.
(5) After 30 min incubation, blood clotting was observed in all 8 experiments with heparin concentrations of 0 and 1 U per ml; in 3 of 8 with 2 U per ml; and in none with greater than or equal to 3 U per ml.
(6) Purpura fulminans is the cutaneous manifestation of acute activation of the clotting mechanism resulting in massive hemorrhage due to an intravascular consumption coagulopathy.
(7) Electron microscopy showed that the clots consist mainly of a suspension of individual fibers, in contrast to clots made from native fibrinogen, which are highly branched.
(8) In testing the hypothesis that Lp(a) can competitively inhibit plasma clot lysis mediated by plasmin, the present study shows that Lp(a) significantly enhanced plasma clot lysis mediated by streptokinase or t-PA.
(9) After adding 125I-labeled fibrinogen to plasma, clots were made by adding thrombin and calcium and were then resuspended in normal plasma containing various concentrations of JTPI-1.
(10) Hematoma clot weighing 10 grams was removed through emergency craniotomy, followed by external decompression.
(11) These data suggest that, in addition to platelet activation, abnormalities of blood clotting, and particularly reduction of antithrombin III, may play a role in the thrombotic tendency associated with homocystinuria.
(12) is related to the presence of adherent clots along cerebral arteries and when severe may lead to cerebral infarction.
(13) Certain of the schistosomes were covered with a dense mass of interconnected blood platelets resembling a temporary haemostatic plug but not a blood clot.
(14) Concanavalin A was employed to study the role of platelet membrane glycoproteins in platelet-fibrin interactions during clot formation.
(15) Venous thrombosis occurred in 7 patients (17.5%) in the Kabi 2165 group, including two high, potentially emboligenic, localizations (5%), and in 4 patients (10%) in the standard heparin group, including 2 potentially emboligenic clots (5%).
(16) The main objective of these experiments was to develop and characterize a new experimental model of venous thrombosis, and determine whether a combination of vascular wall damage (crushing with hemostat clamps) and prolonged stasis produced more reproducible clots than prolonged stasis per se.
(17) The assay shows strong correlation with the immunologic assay for factor XIII catalytic subunit a (r = 0.94), the factor XIII dansylcadaverine assay (r = 0.83), and the factor XIII clot solubility test.
(18) Unlike thrombin, the newly isolated kallikrein-like enzyme did not cause formation of a fibrin clot when fibrinogen was mixed with the enzyme.
(19) It has to be assumed that in calves with respiratory distress syndrome--in analogy to pulmonary immaturity--the blood clotting mechanism is not yet fully developed.
(20) Five other patients with water-insoluble paraproteins were tested; two were clot-inhibitory.
Coagulation
Definition:
(n.) The change from a liquid to a thickened, curdlike, insoluble state, not by evaporation, but by some kind of chemical reaction; as, the spontaneous coagulation of freshly drawn blood; the coagulation of milk by rennet, or acid, and the coagulation of egg albumin by heat. Coagulation is generally the change of an albuminous body into an insoluble modification.
(n.) The substance or body formed by coagulation.
Example Sentences:
(1) This study compared the non-invasive vascular profiles, coagulation tests, and rheological profiles of 46 consecutive cases of low-tension glaucoma with 69 similarly unselected cases of high-tension glaucoma and 47 age-matched controls.
(2) The authors conclude that during the infusion of 5-FU, the rise in FpA activation and reduction in PCa as compared to PCag are compatible with activation of coagulation.
(3) A newborn presenting with persistent umbilical stump bleeding should be screened for factor XIII deficiency when routine coagulation tests prove normal.
(4) It is clear from the data reported here that when used in combination with DEF heparin should be administered at low doses and the coagulation parameters carefully followed.
(5) Erythrocyte filterability, blood viscosity, changes in the blood picture, and three blood coagulation factors (antithrombin III, protein C, and fibrin monomers) were investigated.
(6) Concanavalin A (con A) is a potent inhibitor of coagulant activity of native tissue factor.
(7) On the other hand, the injection of minute quantities of endotoxin into PbAc(2)-sensitized rats invariably resulted in disseminated intravascular coagulation, apparently via a complete activation of the intrinsic pathway.
(8) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
(9) The efforts to identify the initiating reactions of the blood coagulation process have not been unambiguously successful.
(10) Antibodies against factor VIII collected from six patients were studied for their effect on factor-VIII coagulant activity, Willebrand factor activity (WF) and factor-VIII-related antigen.
(11) Fibrinolysis seems to be enhanced in a subset of cancer patients in contrast to blood coagulation.
(12) Occasionally, these aggregates coagulate and contract into a dense gel in the absence of MgATP or CaATP.
(13) The ideal prophylaxis should compensate for the undesired effects of an operation or injury on the coagulation system, without subjecting the patient to the danger of elevated tendency to bleed.
(14) Endoscopic coagulation is a useful adjunct in the treatment of this condition, and is safe, effective, and leaves other options open.
(15) An inhibitor of blood coagulation was detected in 12 patients, and von Willebrand's syndrome was observed in two others.
(16) The activity was not due to plasmin, contact activation, or coagulation factors, since it was fully generated in plasminogen-depleted, factors XII, XI, VII deficient, and prekallikrein-deficient plasmas.
(17) The effects of fetal acidosis (mean pH 6.93) on fetal and maternal blood coagulation were measured.
(18) Systemic blood coagulation was unaffected by single 10000 U doses of heparin administered intraperitoneally in that plasma A-PTT values were not lengthened when measured over the ensuing six hours.
(19) The influence of aztreonam (AZT), a new monobactam antibiotic, on blood coagulation was compared with latamoxef (LMOX), cefoperazon (CPZ), cefotetan (CTT) and ampicillin (ABPC).
(20) After tubal coagulation reversal, these figures were 57% and 6% respectively.