(1) Mutations in most CRT genes confer additional phenotypes, among these are clumpiness, hydroxyurea sensitivity, temperature sensitivity and slow growth.
(2) The entity is characterized by a maturation arrest at the myelocyte stage, strikingly clumpy chromatin, and a clinical course marked primarily by difficulties caused by anemia and thrombocytopenia.
(3) He wears clumpy black shoes instead of the custom-made red slippers favoured by his predecessor, Benedict; refuses to live in the magnificently decorated papal apartments, and drives himself around the city state in a 1984 Renault 4 of the sort favoured by Italian smallholders.
(4) A lesser side might have crumpled, particularly after the clumpy 2-2 draw against Sunderland that left them six points behind the following Wednesday, with only one game in hand.
(5) The ATT serum crossreacted with rat liver nucleoli and PtK1 cell nucleoli in which immunofluorescence labelling displayed a clumpy pattern.
(6) A 34-kd nucleolar protein (fibrillarin) of the U3 RNP complex was positive in immunoblotting of 22 sera (48%), which characteristically produced clumpy nucleolar staining.
(7) With the aid of polarization and electron microscopy, the myocardial-cell changes in the affected zones were classed into four morphological types, as follows: contracture type, intracellular myocytolysis, primary clumpy disintegration of myofibrils, and intravital autolysis of ischaemized cells.
(8) Disruption of the gene caused phenotypes similar to, but more severe than, those caused by missense mutations: high-level constitutivity for invertase, clumpiness, temperature-sensitive growth, alpha-specific mating defects, and failure to homozygous diploids to sporulate.
(9) Electron microscopic description of the characteristic abnormal clumpy chromatin cells is included.
(10) Clumpy or ovoid deposits of amyloid were present within the stroma of 41 epitheliomas, whereas no amyloid was found in the tumor cell islands.
(11) Cells deficient in Chs2 showed clumpy growth and aberrant shape and size.
(12) In addition clumpy grains of c-myc in squamous cell carcinoma appeared more frequently than in squamous metaplasia or dysplasia.
(13) Type 1 cells contained an ovoid dark nucleus with clumpy chromatin and possessed only a very thin rim of cytoplasm.
(14) But I can't deny that in my nylon hockey skirt and clumpy studded boots, my knees covered in mud and my sweaty fringe in my eyes, I felt that I looked too substantial, too challenging.
(15) Remarkably, the spaT mutant colonies revealed a clumpy surface morphology on solid media.
(16) All three patients with diffuse scleroderma had high titers of clumpy pattern antinucleolar antibody on HEp-2 cells.
(17) A homogeneous nucleolar staining pattern was found in 45 of the 64 sera (70.3%), a clumpy fluorescence associated with fibrillarin antibody in 14 (21.8%) and a speckled pattern was found in five of the sera (7.8%).
(18) Strong clumpy fluorescence of nucleoli in the interphase.
(19) In this fashion, we identified a large (90 kilobases) plasmid, pCLP51R, that encodes the lac+ marker, resistance to a lytic phage called LP10G (1pr+), high-frequency conjugal donor ability (hft+), and clumpy growth of host bacteria in broth culture (clu+).
(20) The immunoreactivity was more uniform and diffused for FS proteins and granulated or clumpy for ODF proteins.
Clumsy
Definition:
(superl.) Stiff or benumbed, as with cold.
(superl.) Without skill or grace; wanting dexterity, nimbleness, or readiness; stiff; awkward, as if benumbed; unwieldy; unhandy; hence; ill-made, misshapen, or inappropriate; as, a clumsy person; a clumsy workman; clumsy fingers; a clumsy gesture; a clumsy excuse.
Example Sentences:
(1) In both, objective aggravation occurred in three or more steps over four days, progressing from minor finger clumsiness to total paralysis of the arm.
(2) Since she was 25-year-old, she had had insomnia which accompanied by choked feelings, palpitations, clumsiness of hands and anxiety.
(3) Salmond and his finance secretary, John Swinney, have pushed for Scotland to be given control over corporation tax, excise duties and greater borrowing powers in the new bill, but those measures were rejected as ill thought out and clumsy by the UK government and Labour.
(4) The problem is that, whilst severely affected children can be readily recognized, identification of mildly and moderately clumsy children is difficult.
(5) Clumsy US tactics and policies exacerbated a deteriorating situation.
(6) Several lines from the 1984 song were heavily criticised here and in Africa for being clumsy and patronising, including the one about no rivers flowing in Africa – the continent of the Nile, Congo and Niger.
(7) Ethanol impaired performance in most objective tests and produced clumsiness, muzziness, and mental slowness, but little drowsiness.
(8) The unfairly maligned camel is a model of sleek, practical and elegant design compared with the clumsy creature the coalition has produced.
(9) The arcane wiring when electricity came along, the subsequent clumsy rewiring; the cheap flat conversion in the 1960s; the constant saga of patch and mend from occupants who never have the money or vision to remake the whole thing from scratch - all this, and more, was paralleled on the WCML on an enormous scale.
(10) It is difficult to comprehend the logic of expecting improvements in this agenda while withdrawing half a billion dollars in funding to many service agencies, and leaving them poised precariously at the mercy of a clumsy and poorly executed “advancement” strategy.
(11) DZ but not O 60 was reported to have caused lethargy and clumsiness during subchronic treatment.
(12) A nine year-old girl admitted to our hospital complaining of clumsiness of hands and walking, disability of reading, headache and vomiting.
(13) Her main project is new girl Tai (the late Brittany Murphy) who arrives at school as a clumsy, unconfident "ugly duckling" ripe for making over – allowing the film to indulge in that wonderful 80s teen movie trope: the dressing up montage.
(14) Clinical syndromes were classified according to Fisher's criteria into pure motor hemiparesis (PM), sensorimotor stroke (SM) and ataxic hemiparesis (AH) including dysarthria clumsy hand syndrome.
(15) Observations by parents and teachers rated the clumsy children inferior to their controls in writing, sporting ability and clumsiness.
(16) Even if the move seemed dictatorial in the short term, it served to enshrine a constitution that in the long-term actually curtails Morsi's power – which to the Brotherhood makes his actions well-intentioned, if clumsy.
(17) The children with learning disabilities were divided into two groups--"clumsy" and "nonclumsy"--based on their scores on the motor impairment test.
(18) Fulham were furious in 2012 when Liverpool's attempt to take Clint Dempsey from them saw the Merseyside club deliver clumsy bulletins.
(19) Analysis of the data indicated that, as expected, the clumsy children with learning disabilities scored significantly lower than the children without learning disabilities (the control group).
(20) Abnormal clumsiness in otherwise normal children has often been associated with both perceptual and motor defects, but the cause of this problem remains unclear.