What's the difference between coadjuvant and excipient?
Coadjuvant
Definition:
(a.) Cooperating.
(n.) An adjuvant.
Example Sentences:
(1) We consider that the immunoferon constitutes a coadjuvant therapy to bacterial immunotherapy.
(2) In most cases coadjuvant factors exist predisposing thromboembolic disease.
(3) When coadjuvants are added, mitogenicity increases but in a variable manner among patients.
(4) In conclusion the PGE2 has choleretic action in biliary atresia and could be a coadjuvant treatment to improve the bile flow.
(5) We underline the importance of early diagnosis and effective treatment of the disease as well as of the coadjuvant factors.
(6) To improve the number of stable cures, experiments have been carried out with complementary or coadjuvant techniques whose purpose is to limit intra-operative dissemination of the tumour and to monitor the number of cancer cells that might remain after radical surgery.
(7) Components from the cell wall or bacterial membrane that could act as coadjuvants do not participate in this phenomenon.
(8) Coadjuvant chemotherapy was given to five patients (11.5%) and radiotherapy to one (2.3%).
(9) Attention is also drawn to the fact that all forms of medical management in such cases must be regarded as coadjuvant to the treatment given by the dentist.
(10) These results support a potential role for probucol as a coadjuvant drug in any lipid-lowering antiatherogenic therapy.
(11) Nevertheless, an immune disbalance which could be the coadjuvant factor was founded.
(12) No coadjuvant hormone therapy was instituted in this latter case.
(13) A macromolecular medium, comprised of a mixture of the polymers Ficoll 400 and carboxymethyl cellulose (FMC) is used ad coadjuvant for the reaction.
(14) Insulin is a well known mitogenic coadjuvant able to act sinergistically with other mitogens in the stimulation of fibroblast proliferation under experimental conditions.
(15) The clinical data are coadjuvant, while isolated initial CPK had not value.
(16) The patient was submitted to radical nephrectomy, including the ipsilateral adrenal, and contralateral adrenalectomy, and received coadjuvant steroid replacement therapy.
(17) These findings support the hypothesis that methisoprinol can be an efficient coadjuvant in the treatment of primary Sjögren's syndrome in early stages when there is only functional alteration but no glandular atrophy.
(18) The authors report the use of nifedipine as a coadjuvant drug in the treatment of three patients with uncontrolled epilepsy.
(19) This pathology lacks specific diagnostic tests as well as the assistance rendered by clinical, radiological or ultrasound studies, it will depend on a correct preoperative diagnosis, an extremely difficult task to achieve, or on a diagnostic approximation geared to avoid in the child population the implementation of coadjuvant measures to surgery that will no doubt give rise to unwanted situations in the long run.
(20) DRIF can be a coadjuvant treatment in patients with Parkinson's disease.
Excipient
Definition:
(v. t.) Taking an exception.
(n.) An exceptor.
(n.) An inert or slightly active substance used in preparing remedies as a vehicle or medium of administration for the medicinal agents.
Example Sentences:
(1) Poly(ortho ester) bioerodible polymers are suitable materials for the topical administration of a wide variety of therapeutic agents; varying the nature and amounts of excipients physically incorporated into the polymer will vary the erosion rates from a few hours to many months.
(2) Starch particles are the smallest among the excipients studied.
(3) Concentrations of lactose (4.85 and 4.81%), fat (3.76 and 3.67%), total solids (12.57 and 12.44%), SNF (8.83 and 8.75%), casein (2.56 and 2.53%), and true protein (3.13 and 3.08%) were similar in milks from cows receiving bST and excipient, respectively.
(4) The following results were obtained in the treated forearm versus the untreated forearm (excipient alone): clinically, an increase in skin thickness; by noninvasive techniques, an increase in skin thickness, skin elasticity, skin conductance, and TEWL, and a reduction in the size of the corneocytes.
(5) The results show that the choice of the excipients is basic.
(6) safety of HPCD and its well-characterized chemical composition, suggest that this starch derivative may be a potentially useful excipient for protein drugs intended for parenteral use.
(7) However, the observation that dextran 40 formulations showed poor stability toward aggregation demonstrates that an amorphous excipient system is not a sufficient condition for stability.
(8) However, due to crystallization of the excipients during storage and the resulting decrease in Tg, samples stored at 25 degrees C were also above their Tg during much of the storage period.
(9) The effect of intramuscular injections of two multivitamin preparations, two excipient preparations without vitamins, and a placebo preparation (glycine 2.5%) on serum creatine kinase activity (S-CK) in ten healthy volunteers (three female, seven male) aged between 23 and 25 years was investigated.
(10) The method is precise and selective for nitrazepam in the presence of the tablet excipients and 2-amino-5-nitrobenzophenone, the principal hydrolysis product of nitrazepam.
(11) Solid excipients, cornstarch, and talcum powder when injected intra-arterially decreased flow, and vascular obstruction was shown angiographically.
(12) Gluconolactone contributed least to the degradation of the drug as compared to other excipients studied.
(13) Gluconolactone was evaluated as an excipient for tablets prepared by direct compression using various drugs known to be difficult to compress.
(14) Tolerance was excellent except for mild nausea, probably due to the excipients, in two patients taking nine capsules.
(15) The oral provocation test with the excipient of the commercial preparation was negative; the tolerance to Methyl-Digoxin complete.
(16) The best solvents were then used in the study of different semisolid vehicles for topical use (cetylic excipient, Beeler's base and Carbopol gel), which show different physicochemical characteristics.
(17) In contrast, no significant difference in mean survival was observed between excipient and rHTNF treated animals bearing MCA-38, -101, or -102.
(18) Excipient-treated PIC barrows exhibited faster and more efficient growth (P less than .001) and a higher capacity for carcass protein accretion (P less than .001) but similar rates of lipid deposition compared to excipient-treated NEB barrows.
(19) TIMI Phase 1.5 compared two preparations of rt-PA, the early formulation in liquid excipient ("old" rt-PA) and the new lyophilized form ("new" rt-PA).
(20) Canrenone can be determined by high-speed liquid chromatography in pharmaceutical dosage forms without interference from common excipients or degradation products.