What's the difference between coagulation and dissolution?

Coagulation


Definition:

  • (n.) The change from a liquid to a thickened, curdlike, insoluble state, not by evaporation, but by some kind of chemical reaction; as, the spontaneous coagulation of freshly drawn blood; the coagulation of milk by rennet, or acid, and the coagulation of egg albumin by heat. Coagulation is generally the change of an albuminous body into an insoluble modification.
  • (n.) The substance or body formed by coagulation.

Example Sentences:

  • (1) This study compared the non-invasive vascular profiles, coagulation tests, and rheological profiles of 46 consecutive cases of low-tension glaucoma with 69 similarly unselected cases of high-tension glaucoma and 47 age-matched controls.
  • (2) The authors conclude that during the infusion of 5-FU, the rise in FpA activation and reduction in PCa as compared to PCag are compatible with activation of coagulation.
  • (3) A newborn presenting with persistent umbilical stump bleeding should be screened for factor XIII deficiency when routine coagulation tests prove normal.
  • (4) It is clear from the data reported here that when used in combination with DEF heparin should be administered at low doses and the coagulation parameters carefully followed.
  • (5) Erythrocyte filterability, blood viscosity, changes in the blood picture, and three blood coagulation factors (antithrombin III, protein C, and fibrin monomers) were investigated.
  • (6) Concanavalin A (con A) is a potent inhibitor of coagulant activity of native tissue factor.
  • (7) On the other hand, the injection of minute quantities of endotoxin into PbAc(2)-sensitized rats invariably resulted in disseminated intravascular coagulation, apparently via a complete activation of the intrinsic pathway.
  • (8) The Nd-Yag-Laser seems to be a useful device in transsphenoidal surgery due to its potent coagulation effect and comfortable handling.
  • (9) The efforts to identify the initiating reactions of the blood coagulation process have not been unambiguously successful.
  • (10) Antibodies against factor VIII collected from six patients were studied for their effect on factor-VIII coagulant activity, Willebrand factor activity (WF) and factor-VIII-related antigen.
  • (11) Fibrinolysis seems to be enhanced in a subset of cancer patients in contrast to blood coagulation.
  • (12) Occasionally, these aggregates coagulate and contract into a dense gel in the absence of MgATP or CaATP.
  • (13) The ideal prophylaxis should compensate for the undesired effects of an operation or injury on the coagulation system, without subjecting the patient to the danger of elevated tendency to bleed.
  • (14) Endoscopic coagulation is a useful adjunct in the treatment of this condition, and is safe, effective, and leaves other options open.
  • (15) An inhibitor of blood coagulation was detected in 12 patients, and von Willebrand's syndrome was observed in two others.
  • (16) The activity was not due to plasmin, contact activation, or coagulation factors, since it was fully generated in plasminogen-depleted, factors XII, XI, VII deficient, and prekallikrein-deficient plasmas.
  • (17) The effects of fetal acidosis (mean pH 6.93) on fetal and maternal blood coagulation were measured.
  • (18) Systemic blood coagulation was unaffected by single 10000 U doses of heparin administered intraperitoneally in that plasma A-PTT values were not lengthened when measured over the ensuing six hours.
  • (19) The influence of aztreonam (AZT), a new monobactam antibiotic, on blood coagulation was compared with latamoxef (LMOX), cefoperazon (CPZ), cefotetan (CTT) and ampicillin (ABPC).
  • (20) After tubal coagulation reversal, these figures were 57% and 6% respectively.

Dissolution


Definition:

  • (n.) The act of dissolving, sundering, or separating into component parts; separation.
  • (n.) Change from a solid to a fluid state; solution by heat or moisture; liquefaction; melting.
  • (n.) Change of form by chemical agency; decomposition; resolution.
  • (n.) The dispersion of an assembly by terminating its sessions; the breaking up of a partnership.
  • (n.) The extinction of life in the human body; separation of the soul from the body; death.
  • (n.) The state of being dissolved, or of undergoing liquefaction.
  • (n.) The new product formed by dissolving a body; a solution.
  • (n.) Destruction of anything by the separation of its parts; ruin.
  • (n.) Corruption of morals; dissipation; dissoluteness.

Example Sentences:

  • (1) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
  • (2) A 2-fold increase in the dissolution rate was observed when the same number of particles was immobilized without macrophages.
  • (3) Unaltered surface enamel of extracted human teeth was subjected to tests of resistance to dissolution in 10 mM acetic acid at pH 4.0 and 10 mM EDTA at pH 7.4 in a miniature continuous flow system.
  • (4) At 30 days after injection both stains revealed cellular debris and glial reactions characteristic of cellular dissolution.
  • (5) The in vitro dissolution study carried out using dynamic dialysis revealed that the release of adriamycin from these particles follows a bi-phasic pattern.
  • (6) The retreating rate constants deduced from the dissolution results were well coincident with the values directly determined by the needle penetration method, suggesting good applicability of the proposed equation.
  • (7) However, in some patients absorption of the drug is markedly sensitive to changes in dissolution rate and new pharmacopoeal standards should not be defined until very rapidly-dissolving formulations have been studied.
  • (8) Instead, a repetitive, stepwise dissolution pattern was observed.
  • (9) In ancillary studies, multiple cycles of direct dissolution of UCB crystals revealed a progressive decrease in aqueous solubility of UCB as fine crystals were removed; this effect was minimal in CHCl3.
  • (10) Reductions in dissolution rates in a continuous-flow system could best be interpreted by assuming that they reflected changes in the area of the hydrophilic solid exposed to the solvent.
  • (11) Applications from Serbia, which account for 10% of the total, stem mostly from the dissolution of former Yugoslavia: payment of army reservists, access to savings in present-day Bosnia and Herzegovina, pensions in Kosovo.
  • (12) The minimal advantage in rapidity of stone dissolution offered by tham E over tham is more than offset by the considerably increased potential for toxic side effects.
  • (13) The differences in the amounts of rapidly releasable calcium were attributed to different kinetics of calcium phosphate and calcium oxalate dissolution.
  • (14) The steps in the model are the drug elimination rate in the precornea and anterior chamber, the rate of drug dissolution, the rate of drug penetration into the cornea, and the rate of drug transport into the aqueous humor.
  • (15) Two commercial slow-release potassium chloride tablets, Slow-K and Addi-K have the characteristics of slow-release in the different dissolution conditions.
  • (16) Two consequences of these conditions are (1) patient classification into syndrome types (e.g., phonological dysgraphia, agrammatism, and so forth) can play no useful role in research concerned with issues about the structure of normal cognitive functioning or its dissolution under conditions of brain damage; and (2) only single-patient studies allow valid inferences about the structure of cognitive mechanisms from the analysis of impaired performance.
  • (17) Areas suggestive of cellular dissolution and disorganization were also reported in experimental parathyroids
  • (18) Speaking in Adelaide on Thursday as the government struggles to turn around its polling in South Australia before a possible double dissolution election, the prime minister went on the attack and said Labor was making major policy announcements on the fly.
  • (19) Although all three formulations were shown to have similar dissolution profiles, dissolution of chlorpropamide was pH-dependent in vitro.
  • (20) However, if solubility is considered as a function of pH at equilibrium, i.e., the final pH after the dissolution products have entered the solvent--a model more akin to the in vivo situation--hydroxyapatite is the conspicuously more soluble of the two minerals.