(superl.) Large in bulk, or composed of large parts or particles; of inferior quality or appearance; not fine in material or close in texture; gross; thick; rough; -- opposed to fine; as, coarse sand; coarse thread; coarse cloth; coarse bread.
(1) Epithelial thymoma is characterized by coarse-fiber stroma, perivascular grouping of cell elements and the lack of glycogen in them.
(2) Foveal involvement included coarse foveal granularity, thinning of the foveal retinal pigment epithelium, increasing encirclement of the fovea with focal areas of atrophy, and minimal macular drusen.
(3) In 11 of these 20 patients, visual sensitivity to detail of medium coarseness was markedly degraded, even though sensitivity to both coarse and fine detail was unimpaired.
(4) In it he translated Trump’s coarse ramblings into charming straight talk and came up with the phrase “truthful hyperbole”, which captures brilliantly an approach to business and politics in which everything is the greatest, the most beautiful.
(5) Characteristic coarse facial features and shortness of stature were observed in all cases.
(6) The pulp cavity is reduced in size with age (maturation stage), in which the characteristic three vascular layers are changed into a one-layer coarse terminal capillary network which converges directly with the main venules.
(7) (3) Their operative findings were different from ordinary Graves' goiters in that colors of the goiter were yellow-red or gray-red, surface was rough and coarse, consistency was firm, and adhesions with the adjacent connective tissue were noted.
(8) Attempts were made to purify the LH-releasing substance extracted from the leaves of Avena sativa by means of two-step chromatographic procedures using a weakly acidic ion-exchange resin (CG-50,type II) and DEAE-Sephadex A-25 (coarse) with successful results.
(9) First-time measurements of the potentially toxic inorganic species of arsenic (arsenite and arsenate) have been obtained in fine (less than 2.5 microns AD) and coarse (greater than 2.5 microns AD) atmospheric particles in the Los Angeles area.
(10) An abnormal great number of microtubules and coarsed fibers were frequently randomly scattered throughout the cytoplasmic droplet.
(11) Motorized linear slides used as micromanipulators for biological use suffer from 3 problems: vibration at low speed, poor ergonomic design of the controller and slow coarse positioning.
(12) Each antibody stained 2 populations of cortical nonpyramidal neurons: (1) A small number of large, intensely stained cells that give rise to long, coarsely beaded processes; (2) a relatively large number of small, lightly stained cells that are embedded in dense plexuses of stained punctate profiles.
(13) In the Pagalunggan subdistrict, all females used uniodised salt with 17.6% using fine salt, 20% using coarse salt and the remainder using both fine and coarse salt.
(14) Thygeson's keratitis is characterized by a coarse punctate epithelial keratitis with almost no hyperaemia of the conjunctiva.
(15) The particles selected by CYBEST as "abnormal cells" at the stage of coarse scanning were examined by direct microscopy to determine whether they were actural cells or not.
(16) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(17) Coarse, linear densities are also observed, and pleural effusion is seen in many patients.
(18) Serves 4 100g butter, at room temperature 150g flour 50g ground almonds 30g suet 1 egg yolk 50g cooked chestnuts, chopped 5 tbsp chopped fresh thyme Salt and black pepper For the leeks 1kg leeks, trimmed 100g butter Salt and pepper 200ml double cream 1 tsp nutmeg 1 To make the crumble topping, work the butter into the flour until it resembles coarse breadcrumbs, then add the ground almonds and suet.
(19) 400g cooked or tinned butterbeans 1 tsp ground cumin 10ml lemon juice ¼ clove garlic, peeled and finely minced 1 small handful picked flat-leaf parsley, finely chopped 1 tbsp plain flour (gluten-free flour also works fine) 1 tsp salt 1 egg 1 spring onion, trimmed and finely sliced 50g breadcrumbs 100g feta (or other crumbly goat's or sheep's cheese) Put the butterbeans, cumin, lemon juice, garlic, parsley, flour, salt and egg in a food processor and blitz to a coarse paste: you don't want the mix fully pureed, otherwise the burgers will be too wet and will fall apart on the grill.
(20) In women who received free-silicone injections, coarse calcifications developed in three, and gross nodularity with calcified silicone granulomas developed in one.
Coarsen
Definition:
(v. t.) To make coarse or vulgar; as, to coarsen one's character.
Example Sentences:
(1) Lesions observed in the small bowel included fixity of bowel loops, thickening of the wall, coarsening of the mucosal pattern and strictures.
(2) They hang pretty strangely, these garments of Britannia: if our decline is down to the loss of empire, how can we call that a coarsening?
(3) Deposits of slightly coarsened reaction product (RP) appeared and accumulated on the abluminal surface.
(4) Radiographic appearances consisted of minimal trabecular coarsening in the patella of nearly normal size and progressed to considerable cortical thickening and osteoblastic remodeling in a dramatically enlarged patella.
(5) Dilatation of the endoplasmic reticulum cavities, an increase in the number of ribosomes near bacteria, deformation of mitochondria and coarsening of cristae were revealed in phagocytosis of Past.
(6) The main side-effects were fluid retention (in eight) and hypertrichosis (in ten), accompanied in some by a peculiar coarsening of the facial features.
(7) Whipple's disease is characterized morphologically by macrophages in the small intestine which store PAS-postive material, as well as coarsening and atrophy of the intestinal villi, with pseudocystic cavitations.
(8) "When literature exists, perhaps we do not notice how important it is, but when it does not exist, our lives become coarsened and brutal.
(9) Acromegaly is characterized by coarsening of facial features, acanthosis nigricans, hypertrichosis and oily skin.
(10) At P 5, coarsened RP was diffusely observed on the luminal and abluminal surfaces.
(11) Gastroduodenoscopy then demonstrated duodenal polyps and massive coarsening of the gastric folds due to infiltration.
(12) The earliest radiological changes were found after six months, at the end of the second scintigraphic peak; they consisted of coarsening and blurring of the trabeculae, nonhomogeneous spotty mineralisation and endosteal scalloping.
(13) "What troubles me about Grand Theft Auto V," sighs Delingpole, "is not just the message it sends out to youngsters (drugs are cool; crime pays; violence is fun), but what it says about the coarsening, the decadence and the hopelessness of our modern culture."
(14) The tabloid newspapers, their "scurillity", are so "consonant with British decline … the general coarsening of British nature".
(15) Of course, cheap comparisons coarsen our collective conversation.
(16) Two investigators were asked to evaluate independently the echogenicity, coarsening and inhomogeneity of the hepatic echo pattern in a semi-quantitative manner; they had no knowledge of the diagnosis and used the same apparatus.
(17) Osteomalacia presents radiographically as deossification, coarsening of the trabecular pattern, and pseudofractures.
(18) Sucralfate should also be evaluated in those difficult clinical conditions known to be resistant to any therapeutic attempt with currently available drugs, such as erosive varioliform gastritis and hypertrophic gastropathy with heavy inflammation of the mucosa and giant coarsening of the gastric rugae.
(19) Gradually he relaxed - and slightly coarsened - into the role his new admirers seemed to want, into a globetrotting, tax-exiled celebrity who told uproarious tales in funny foreign voices, into the Hercule Poirot film series, which allowed him painfully little range or scope.
(20) Widening of the diameter of the bone and loss of cortical medullary distinction with a mottled coarsening of the trabecular pattern are the most characteristic features.